Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Imke Oltmann-Norden"'
Publikováno v:
Electrophoresis5 References. 42(14-15)
SDS gel electrophoresis is a commonly used approach for monitoring purity and apparent molecular mass (Mr) of proteins, especially in the field of quality control of biopharmaceutical proteins. The technological installation of CE-SDS as the replacem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1429d03e5d505b2f5ba3578aecee5c4
https://pubmed.ncbi.nlm.nih.gov/33956358
https://pubmed.ncbi.nlm.nih.gov/33956358
Publikováno v:
Electrophoresis5 References. 42(3)
The development of capillary electrophoresis, especially CE-SDS devices, has led CE-SDS to become an established tool in a wide range of applications in the analysis of biopharmaceuticals and is increasingly replacing its method of origin, SDS-PAGE.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cc287a206992ce8cb5399b1fe6c7478
https://pubmed.ncbi.nlm.nih.gov/33185281
https://pubmed.ncbi.nlm.nih.gov/33185281
Publikováno v:
Analytical Biochemistry. 530:94-103
This work presents an extensive parameter list that facilitates a survey of biosensor performance using Biacore instruments for kinetic binding studies. Six long term measurements were performed using a strongly interacting antigen-antibody (β2 micr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10281dc4d7f97a511ad97d27afb0f16f
https://doi.org/10.1016/j.ab.2017.05.009
https://doi.org/10.1016/j.ab.2017.05.009
Autor:
Holger Zagst, Tatsuya Kato, Jian Xu, Enoch Y. Park, Hermann Wätzig, Imke Oltmann-Norden, Robert Minkner
Publikováno v:
Journal of Chromatography B. 1138:121964
The silkworm, Bombyx mori, is a promising expression system for the production of recombinant proteins, but the purification of these proteins is not easy because of the large amount of host proteins present. To investigate purity, recovery and scale
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e38210622200831a55ef135173d6735
http://hdl.handle.net/10297/00027025
http://hdl.handle.net/10297/00027025
Autor:
Markus Nachbar, Sami El Deeb, Franziska Steinicke, Hassan M. Albishri, Deia Abd El-Hady, Frank M. Böckler, Knut Baumann, Hermann Wätzig, Imke Oltmann-Norden, Thomas E. Exner, Hassan A. Alhazmi
Publikováno v:
Journal of Computer-Aided Molecular Design. 29:847-865
Despite its importance and all the considerable efforts made, the progress in drug discovery is limited. One main reason for this is the partly questionable data quality. Models relating biological activity and structures and in silico predictions re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3ef65a430dc19b1aa87c4f4c24f4e1b
https://doi.org/10.1007/s10822-015-9851-6
https://doi.org/10.1007/s10822-015-9851-6
Autor:
Hildegard Geyer, Rudolf Geyer, Martina Mühlenhoff, Imke Oltmann-Norden, Herbert Hildebrandt, Sebastian P. Galuska, Rita Gerardy-Schahn
Publikováno v:
Journal of Biological Chemistry. 283:1463-1471
Polysialic acid (polySia), a post-translational modification of the neural cell adhesion molecule (NCAM), is the key regulator of NCAM-mediated functions and crucial for normal brain development, postnatal growth, and survival. Two polysialyltransfer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::574841e5bf7865e6376371628f25a14c
https://doi.org/10.1074/jbc.m708463200
https://doi.org/10.1074/jbc.m708463200
Autor:
Imke Oltmann-Norden, Katharina Stummeyer, Almut Günzel, Heike Claus, Friedrich Freiberger, Willie F. Vann, Martina Mühlenhoff, Justine Vionnet, Ulrich Vogel, Rita Gerardy-Schahn
Publikováno v:
Molecular Microbiology
The extracellular polysaccharide capsule is an essential virulence factor of Neisseria meningitidis, a leading cause of severe bacterial meningitis and sepsis. Serogroup B strains, the primary disease causing isolates in Europe and America, are encap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e428d2b915e71eff96fab62c57ba02c
https://doi.org/10.1111/j.1365-2958.2007.05862.x
https://doi.org/10.1111/j.1365-2958.2007.05862.x
Autor:
Rita Gerardy-Schahn, Birgit Weinhold, Sebastian P. Galuska, Rudolf Geyer, Imke Oltmann-Norden, Herbert Hildebrandt, Hildegard Geyer, Klaus Kuchelmeister, Martina Mühlenhoff
Publikováno v:
Journal of Biological Chemistry. 281:31605-31615
The post-translational modification of the neural cell adhesion molecule (NCAM) by polysialic acid (polySia) represents a remarkable example of dynamic modulation of homo- and heterophilic cell interactions by glycosylation. The synthesis of this uni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d59546ed979564cbdd3501e1821bdf9a
https://doi.org/10.1074/jbc.m606516200
https://doi.org/10.1074/jbc.m606516200
Autor:
Imke Oltmann-Norden, Herbert Hildebrandt, Katinka Eggers, Hildegard Geyer, Sebastian P. Galuska, Maike Hartmann, Manuela Rollenhagen, Birgit Weinhold, Moritz Kaup, Martina Mühlenhoff, Miriam Schiff, Rudolf Geyer
Among the large set of cell surface glycan structures, the carbohydrate polymer polysialic acid (polySia) plays an important role in vertebrate brain development and synaptic plasticity. The main carrier of polySia in the nervous system is the neural
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd51fd166389bfe8dc51fa9b8f82ea5c
https://publica.fraunhofer.de/handle/publica/223870
https://publica.fraunhofer.de/handle/publica/223870
Autor:
Rita Gerardy-Schahn, Martina Mühlenhoff, Imke Oltmann-Norden, Herbert Hildebrandt, Hannelore Burkhardt, Iris Röckle, Birgit Weinhold
Publikováno v:
Brain : a journal of neurology. 132(Pt 10)
The neural cell adhesion molecule (NCAM) and its post-translational modification polysialic acid (polySia) are broadly implicated in neural development. Mice lacking the polysialyltransferases ST8SiaII and ST8SiaIV are devoid of polySia, and show sev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9f0faf566fe6d676d0dd449b87816fd
https://pubmed.ncbi.nlm.nih.gov/19443631
https://pubmed.ncbi.nlm.nih.gov/19443631