Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Imke Hansen-Wester"'
Autor:
Francesca Ros, Sonja Offner, Stefan Klostermann, Irmgard Thorey, Helmut Niersbach, Sebastian Breuer, Grit Zarnt, Stefan Lorenz, Juergen Puels, Basile Siewe, Nicole Schueler, Tajana Dragicevic, Dominique Ostler, Imke Hansen-Wester, Valeria Lifke, Brigitte Kaluza, Klaus Kaluza, Wim van Schooten, Roland Buelow, Alain C Tissot, Josef Platzer
Publikováno v:
mAbs, Vol 12, Iss 1 (2020)
Transgenic animals incorporating human antibody genes are extremely attractive for drug development because they obviate subsequent antibody humanization procedures required for therapeutic translation. Transgenic platforms have previously been estab
Externí odkaz:
https://doaj.org/article/eb4cfd37c8a244a096d64b9303c73a7f
Autor:
Klaus Kaluza, Sebastian Breuer, Roland Buelow, Grit Zarnt, Nicole Schueler, Valeria Lifke, Basile Siewe, Alain Tissot, Irmgard Thorey, Stefan Lorenz, Dominique Ostler, Josef Platzer, Brigitte Kaluza, Francesca Ros, Juergen Puels, Tajana Dragicevic, Sonja Offner, Imke Hansen-Wester, Stefan Klostermann, Helmut Niersbach, Wim Van Schooten
Publikováno v:
mAbs
article-version (VoR) Version of Record
article-version (VoR) Version of Record
Transgenic animals incorporating human antibody genes are extremely attractive for drug development because they obviate subsequent antibody humanization procedures required for therapeutic translation. Transgenic platforms have previously been estab
Autor:
Bruce A. Vallance, Caixia Ma, Michael Hensel, Aaron Bestor, Olivia Steele-Mortimer, Imke Hansen-Wester, Leigh A. Knodler
Publikováno v:
Infection and Immunity. 73:7027-7031
Plasmid vectors and fluorescent protein reporter systems are commonly used in the study of bacterial pathogenesis. Here we show that they can impair the ability of Salmonella enterica serovar Typhimurium to productively infect either cultured mammali
Publikováno v:
Infection and Immunity. 72:2879-2888
The type III secretion system (T3SS) encoded by the Salmonella pathogenicity island 2 (SPI2) has a central role in systemic infections by Salmonella enterica and for the intracellular phenotype. Intracellular S. enterica uses the SPI2-encoded T3SS to
Autor:
Michael Hensel, Imke Hansen-Wester
Publikováno v:
Infection and Immunity. 70:2351-2360
Acquisition of genomic elements by horizontal gene transfer represents an important mechanism in the evolution of bacterial species. Pathogenicity islands are a subset of horizontally acquired elements present in various pathogens. These elements are
Publikováno v:
Infection and Immunity. 70:1619-1622
The type III secretion system encoded by Salmonella pathogenicity island 2 (SPI2) translocates Salmonella translocated effectors (STE) into host cells. STE are encoded by genes outside of SPI2. The distribution of STE loci within the salmonellae was
Publikováno v:
The Journal of experimental medicine. 195(9)
Salmonella typhimurium causes an invasive disease in mice that has similarities to human typhoid. A type III protein secretion system encoded by Salmonella pathogenicity island 2 (SPI2) is essential for virulence in mice, as well as survival and mult
Autor:
Michael Hensel, Imke Hansen-Wester
Publikováno v:
Microbes and infection. 3(7)
Salmonella enterica harbours two Salmonella pathogenicity islands (SPIs) each encoding a type III secretion system for virulence proteins. SPI1 is required for invasion, while systemic infections and intracellular accumulation of Salmonella are depen