Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Imke Grimmelmann"'
Autor:
Nora Möhn, Susann Mahjoub, Laura Duzzi, Emily Narten, Lea Grote‐Levi, Gudrun Körner, Tabea Seeliger, Gernot Beutel, Benjamin‐Alexander Bollmann, Thomas Wirth, André Huss, Hayrettin Tumani, Imke Grimmelmann, Ralf Gutzmer, Philipp Ivanyi, Thomas Skripuletz, ICOG‐CCCH (Immune Cooperative Oncology Group; Comprehensive Cancer Center Hannover)
Publikováno v:
Cancer Medicine, Vol 12, Iss 8, Pp 9373-9383 (2023)
Abstract Background Oncological patients can benefit substantially from treatment with immune checkpoint inhibitors (ICI). However, there is a growing awareness of immune‐related adverse events (irAE). Especially ICI‐mediated neurological adverse
Externí odkaz:
https://doaj.org/article/fc59d8e698d2445d874c2607cff2f8e4
Autor:
Dirk Schadendorf, Lucie Heinzerling, Jessica C Hassel, Lisa Zimmer, Ralf Gutzmer, Alexander Kreuter, Andrea Forschner, Elisabeth Livingstone, Bastian Schilling, Selma Ugurel, Peter Mohr, Thilo Gambichler, Patrick Terheyden, Sebastian Haferkamp, Friedegund Meier, Claudia Pfoehler, Dirk Debus, Rudolf Herbst, Carmen Loquai, Frank Meiss, Carsten Weishaupt, Jochen Utikal, Martin Kaatz, Jens Ulrich, Edgar Dippel, Michael Weichenthal, Maike Trommer, Jürgen Christian Becker, Ulrike Leiter, Cindy Franklin, Christoffer Gebhardt, Katharina Kahler, Leonie Bluhm, Imke Grimmelmann, Marlene Garzarolli, Dorothee Nashan, Michael Sachse, Julia Welzel, Gerhard Weyandt, Susanne Horn, Fabian Ziller, Harald Löffler, Stephan Grabbe, Gaston Schley, Georg Lodde, Jan-Malte Placke, Anca Sindrilaru
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 4 (2023)
Background Despite the availability of effective systemic therapies, a significant number of advanced melanoma patients develops brain metastases. This study investigated differences in incidence and time to diagnosis of brain metastasis and survival
Externí odkaz:
https://doaj.org/article/78c357556a7d4fdbba1d2ae0e5644ffc
Autor:
Dirk Schadendorf, Lucie Heinzerling, Lisa Zimmer, Ralf Gutzmer, Alexander Kreuter, Andrea Forschner, Elisabeth Livingstone, Selma Ugurel, Alexander Roesch, Peter Mohr, Thilo Gambichler, Patrick Terheyden, Sebastian Haferkamp, Friedegund Meier, Claudia Pfoehler, Dirk Debus, Rudolf Herbst, Frank Meiss, Carsten Weishaupt, Jochen Utikal, Martin Kaatz, Jens Ulrich, Edgar Dippel, Michael Weichenthal, Maike Trommer, Ulrike Leiter, Kerstin Schatton, Cindy Franklin, Leonie Bluhm, Imke Grimmelmann, Marlene Garzarolli, Dorothee Nashan, Michael Sachse, Julia Welzel, Gerhard Weyandt, Eren Celik, Iris Helfrich, Susanne Horn
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 6 (2022)
Externí odkaz:
https://doaj.org/article/31d907c2fd3a4ebe9ebbc4ec2bbec6d3
Autor:
Viola K. DeTemple, Jessica C. Hassel, Michael M. Sachse, Imke Grimmelmann, Ulrike Leiter, Christoffer Gebhardt, Julia Eckardt, Claudia Pföhler, Yenny Angela, Hanna Hübbe, Ralf Gutzmer
Publikováno v:
Cancers, Vol 14, Iss 21, p 5469 (2022)
For patients with advanced basal cell carcinoma (aBCC) first-line treatment with hedgehog inhibitors (HHIs) and second-line treatment with PD1 inhibitors (PD1i) is available, offering combination and sequencing options. Here, we focus on the efficacy
Externí odkaz:
https://doaj.org/article/cb53ee231e924e76b39eb1018db036cd
Autor:
Lena Margarethe Wulfken, Jürgen Christian Becker, Rami Hayajneh, Annette Doris Wagner, Katrin Schaper-Gerhardt, Nina Flatt, Imke Grimmelmann, Ralf Gutzmer
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
IntroductionCheckpoint-Inhibition (CPI) with PD-1- and PD-L1-inhibitors is a well-established therapy for advanced stage melanoma patients. CPI mainly acts via T-lymphocytes. However, recent literature suggests also a role for B cells modulating its
Externí odkaz:
https://doaj.org/article/60633f4630ff4b78a6fe51d23dfaff1e
Autor:
Peter Mohr, Emilie Scherrer, Chalid Assaf, Marc Bender, Carola Berking, Sheenu Chandwani, Thomas Eigentler, Imke Grimmelmann, Ralf Gutzmer, Sebastian Haferkamp, Jessica C. Hassel, Axel Hauschild, Rudolf Herbst, Ruixuan Jiang, Katharina C. Kähler, Clemens Krepler, Alexander Kreuter, Ulrike Leiter, Carmen Loquai, Friedegund Meier, Claudia Pföhler, Anja Rudolph, Dirk Schadendorf, Maximo Schiavone, Gaston Schley, Patrick Terheyden, Selma Ugurel, Jens Ulrich, Jochen Utikal, Carsten Weishaupt, Julia Welzel, Michael Weichenthal
Publikováno v:
Cancers, Vol 14, Iss 7, p 1804 (2022)
Knowledge on the real-world characteristics and outcomes of pembrolizumab-treated advanced melanoma patients in Germany and on the value of different real-world endpoints as surrogates for overall survival (OS) is limited. A sample of 664 pembrolizum
Externí odkaz:
https://doaj.org/article/bb3e4f856a0049c7af31270a7328f54b
Autor:
Jacqueline Niewolik, Marie Mikuteit, Dominik Schröder, Stephanie Heinemann, Gloria Heesen, Frank Müller, Alexandra Dopfer-Jablonka, Imke Grimmelmann, Sandra Steffens
Publikováno v:
Die Dermatologie. 74:108-113
Zusammenfassung Hintergrund Die getroffenen Maßnahmen zur Eindämmung der Ausbreitung der Coronavirus-2019-Erkrankung (COVID-19) schränken die sozialen Teilhabemöglichkeiten vieler Menschen ein. Insbesondere Menschen mit chronischen Erkrankungen w
Autor:
Jacqueline Niewolik, Marie Mikuteit, Anne Cossmann, Kai Vahldiek, Ralf Gutzmer, Frank Müller, Dominik Schröder, Stephanie Heinemann, Georg M.N. Behrens, Alexandra Dopfer-Jablonka, Sandra Steffens, Imke Grimmelmann
Publikováno v:
Oncology. 100:392-398
Background: Immunogenicity of SARS-CoV-2 vaccines is modestly impaired in cancer patients due to a generally weakened immune system. Immune checkpoint inhibitors (ICI) are expected to enhance immune response. This has already been described to be the
Autor:
Cindy Franklin, Peter Mohr, Leonie Bluhm, Friedegund Meier, Marlene Garzarolli, Michael Weichenthal, Katharina Kähler, Imke Grimmelmann, Ralf Gutzmer, Jochen Utikal, Patrick Terheyden, Rudolf Herbst, Sebastian Haferkamp, Claudia Pfoehler, Andrea Forschner, Ulrike Leiter, Fabian Ziller, Frank Meiss, Jens Ulrich, Alexander Kreuter, Christoffer Gebhardt, Julia Welzel, Bastian Schilling, Martin Kaatz, Karin Scharfetter-Kochanek, Edgar Dippel, Dorothee Nashan, Michael Sachse, Carsten Weishaupt, Harald Löffler, Thilo Gambichler, Carmen Loquai, Lucie Heinzerling, Stephan Grabbe, Dirk Debus, Gaston Schley, Jessica C Hassel, Gerhard Weyandt, Maike Trommer, Georg Lodde, Jan-Malte Placke, Lisa Zimmer, Elisabeth Livingstone, Jürgen Christian Becker, Susanne Horn, Dirk Schadendorf, Selma Ugurel
BackgroundDespite the availability of effective systemic therapies, a significant number of advanced melanoma patients develops brain metastases. This study investigated differences in incidence and time to diagnosis of brain metastasis and survival
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::861f61bac67444b59bcad9028154c312
https://www.ncbi.nlm.nih.gov/pubmed/37028819
https://www.ncbi.nlm.nih.gov/pubmed/37028819
Publikováno v:
Journal of Dermatological Science. 104:30-38
Background Organ transplant recipients show a high incidence for the formation of cutaneous squamous cell carcinoma (cSCC), while sirolimus appears to reduce the risk. GRO-α is a chemokine, which is overexpressed in many tumor entities and associate