Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Imene Tabet"'
Autor:
Carolina Velazquez, Esin Orhan, Imene Tabet, Lise Fenou, Béatrice Orsetti, José Adélaïde, Arnaud Guille, Simon Thézénas, Evelyne Crapez, Pierre-Emmanuel Colombo, Max Chaffanet, Daniel Birnbaum, Claude Sardet, William Jacot, Charles Theillet
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
BackgroundAbout 15% of Triple-Negative-Breast-Cancer (TNBC) present silencing of the BRCA1 promoter methylation and are assumed to be Homologous Recombination Deficient (HRD). BRCA1-methylated (BRCA1-Me) TNBC could, thus, be eligible to treatment bas
Externí odkaz:
https://doaj.org/article/e04a4c983fe14d5c8fffd7f0ddb98082
Regulation of RAD51 at the Transcriptional and Functional Levels: What Prospects for Cancer Therapy?
Publikováno v:
Cancers
Cancers, Vol 13, Iss 2930, p 2930 (2021)
Cancers, Vol 13, Iss 2930, p 2930 (2021)
Simple Summary RAD51 is an essential gene for cell survival. Its function is central to DNA repair and it protects cells from life-threatening damage to the genome. Interestingly, RAD51 is expressed at high levels in a large proportion of cancers, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f959c22c6d7a89dca4132c6eab2ab6df
https://pubmed.ncbi.nlm.nih.gov/34208195
https://pubmed.ncbi.nlm.nih.gov/34208195
Autor:
Lise Fenou, Charles Theillet, Laura Boudarel, Imene Tabet, Esin Orhan, Carolina Velázquez, William Jacot, Claude Sardet
Publikováno v:
The 1st International Electronic Conference on Cancers: Exploiting Cancer Vulnerability by Targeting the DNA Damage Response.
In triple negative breast cancer (TNBC), chemotherapy is the only systemic treatment and sustained remissions are rare. We propose to widen therapeutic options. About 30% of TNBC tumors are BRCA1-deficient, presenting defective DNA repair and increas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a842c574e62b9f6daff0cafc4ece6e67
https://doi.org/10.3390/iecc2021-09226
https://doi.org/10.3390/iecc2021-09226
Autor:
Esin Orhan, Charles Theillet, Lise Fenou, Claude Sardet, William Jacot, Carolina Velázquez, Laura Boudarel, Imene Tabet
Publikováno v:
The 1st International Electronic Conference on Cancers: Exploiting Cancer Vulnerability by Targeting the DNA Damage Response.
Triple-negative breast cancer (TNBC), representing 15% of breast carcinomas, is an aggressive breast cancer subtype with a high probability of metastasis and limited treatment options. Noticeably, BRCA-deficiency occurs in 25% of the TNBCs and result
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::32a929ad2ecf2c2793fa0c269fad1004
https://doi.org/10.3390/iecc2021-09212
https://doi.org/10.3390/iecc2021-09212
Autor:
imene tabet
Publikováno v:
imene tabet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::9ca2ee7ce4d7699240db3932190f8393
https://ejgso.canceropole-gso.org/backoffice/conference/media_library/113
https://ejgso.canceropole-gso.org/backoffice/conference/media_library/113
