Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Imene Ait Mohamed Amar"'
Autor:
Imene Ait Mohamed Amar, Steve Huvelle, Emmanuel Douez, Stéphanie Letast, Sylvain Henrion, Marie-Claude Viaud-Massuard, Nicolas Aubrey, Emilie Allard-Vannier, Nicolas Joubert, Caroline Denevault-Sabourin
Publikováno v:
European Journal of Medicinal Chemistry. 229:114063
Antibody-drug conjugates (ADCs) are targeted therapies, mainly used in oncology, consisting in a three-component molecular architecture combining a highly potent drug conjugated via a linker onto a monoclonal antibody (mAb), designed for the selectiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faaa5ea5206311fac941fcd83fc247c5
https://doi.org/10.1016/j.ejmech.2021.114063
https://doi.org/10.1016/j.ejmech.2021.114063
Autor:
Louis Jolivet, Imène Ait Mohamed Amar, Catherine Horiot, Fanny Boursin, Cyril Colas, Stéphanie Letast, Caroline Denevault-Sabourin, Emilie Allard-Vannier, Nicolas Joubert, Nicolas Aubrey
Publikováno v:
Pharmaceutics, Vol 14, Iss 8, p 1524 (2022)
Antibody–drug conjugates (ADCs) derived from a full immunoglobulin-G (IgG) are associated with suboptimal solid-tumor penetration and Fc-mediated toxicities. Antibody fragment–drug conjugates (FDCs) could be an alternative. Nevertheless, innovati
Externí odkaz:
https://doaj.org/article/15b7c6d9bacf44478b679c4b9bf364c0
Autor:
Valentina Corvaglia, Imène Ait Mohamed Amar, Véronique Garambois, Stéphanie Letast, Aurélie Garcin, Céline Gongora, Maguy Del Rio, Caroline Denevault-Sabourin, Nicolas Joubert, Ivan Huc, Philippe Pourquier
Publikováno v:
Pharmaceuticals, Vol 14, Iss 7, p 624 (2021)
Inhibition of protein–DNA interactions represents an attractive strategy to modulate essential cellular functions. We reported the synthesis of unique oligoamide-based foldamers that adopt single helical conformations and mimic the negatively charg
Externí odkaz:
https://doaj.org/article/cf02bd029f4647c98225f8673b64d484