Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Imari Mimura"'
Autor:
Rika Miura, Imari Mimura, Hanako Saigusa, Tomotaka Yamazaki, Fumiaki Tanemoto, Yu Kurata, Dai Sato, Tetsuhiro Tanaka, Masaomi Nangaku
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Epigenetic modifications such as DNA methylation, histone modifications, and chromatin structures in the kidney contribute towards the progression of chronic kidney disease (CKD). In this study, the role of chromatin remodeling factor inosit
Externí odkaz:
https://doaj.org/article/bc4dc54eb2bb45cdb3375f64239326ce
Autor:
Marie Ito, Gloria Michelle Ducasa, Judith David Molina, Javier Varona Santos, Shamroop Kumar Mallela, Jin Ju Kim, Mengyuan Ge, Alla Mitrofanova, Alexis Sloan, Sandra Merscher, Imari Mimura, Alessia Fornoni
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Decreased ATP Binding Cassette Transporter A1 (ABCA1) expression and caspase-4-mediated noncanonical inflammasome contribution have been described in podocytes in diabetic kidney disease (DKD). To investigate a link between these pathways, w
Externí odkaz:
https://doaj.org/article/9ff64306c5904d43921755a62b6da09d
Autor:
Yoshiyasu Ogura, Imari Mimura
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Accumulation of somatic hematopoietic stem cell mutations with aging has been revealed by the recent genome-wide analysis. Clonal expansion, known as clonal hematopoiesis of indeterminate potential (CHIP), is a premalignant condition of hematological
Externí odkaz:
https://doaj.org/article/bd54f175650043d481a4e5f0ee10f807
Publikováno v:
Physiological Reports, Vol 11, Iss 17, Pp n/a-n/a (2023)
Abstract Epidemiological studies have shown that patients who recovered from acute kidney injury (AKI) may subsequently develop chronic kidney disease (CKD). AKI is primarily caused by renal hypoxia, and it causes epigenetic alterations, known as hyp
Externí odkaz:
https://doaj.org/article/fce23d0b76bc442a88a2d700f8114393
Autor:
Taisuke Ishii, Imari Mimura, Koji Nagaoka, Akihiro Naito, Takehito Sugasawa, Ryohei Kuroda, Daisuke Yamada, Yasuharu Kanki, Haruki Kume, Tetsuo Ushiku, Kazuhiro Kakimi, Tetsuhiro Tanaka, Masaomi Nangaku
Publikováno v:
Cell Death Discovery, Vol 8, Iss 1, Pp 1-18 (2022)
Abstract Chronic kidney disease (CKD) affects kidney cancer patients’ mortality. However, the underlying mechanism remains unknown. M2-like macrophages have pro-tumor functions, also exist in injured kidney, and promote kidney fibrosis. Thus, it is
Externí odkaz:
https://doaj.org/article/fea4fd389da749cf83f77efa217dce65
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Epigenetic memory, which refers to the ability of cells to retain and transmit epigenetic marks to their daughter cells, maintains unique gene expression patterns. Establishing programmed epigenetic memory at each stage of development is required for
Externí odkaz:
https://doaj.org/article/6297ae8ded114300a65ec94b4782dfa6
Autor:
Fumiaki Tanemoto, Imari Mimura
Publikováno v:
Pharmaceuticals, Vol 15, Iss 2, p 123 (2022)
Acute kidney injury (AKI) was previously thought to be a merely transient event; however, recent epidemiological evidence supports the existence of a causal relationship between AKI episodes and subsequent progression to chronic kidney disease (CKD).
Externí odkaz:
https://doaj.org/article/1d314603b5e34d9d90b28c1fca4c6d23
Publikováno v:
Journal of Pharmacological Sciences, Vol 115, Iss 4, Pp 453-458 (2011)
The hypoxia response regulated primarily by hypoxia-inducible factor (HIF) influences metabolism, cell survival, and angiogenesis to maintain biological homeostasis. In addition to the traditional transcriptional regulation by HIF, recent studies hav
Externí odkaz:
https://doaj.org/article/ded22060f9404ba1975f02c0b1c25c5e
Publikováno v:
Behavioural Neurology, Vol 19, Iss 3, Pp 93-106 (2008)
Objective: To clarify whether agraphia or alexia occurs in lesions of the left posterior middle temporal gyrus.
Externí odkaz:
https://doaj.org/article/d16b61fa81624912acd77178de0b13c0
Autor:
Takashi Maejima, Tsuyoshi Inoue, Yasuharu Kanki, Takahide Kohro, Guoliang Li, Yoshihiro Ohta, Hiroshi Kimura, Mika Kobayashi, Akashi Taguchi, Shuichi Tsutsumi, Hiroko Iwanari, Shogo Yamamoto, Hirofumi Aruga, Shoulian Dong, Junko F Stevens, Huay Mei Poh, Kazuki Yamamoto, Takeshi Kawamura, Imari Mimura, Jun-ichi Suehiro, Akira Sugiyama, Kiyomi Kaneki, Haruki Shibata, Yasunobu Yoshinaka, Takeshi Doi, Akimune Asanuma, Sohei Tanabe, Toshiya Tanaka, Takashi Minami, Takao Hamakubo, Juro Sakai, Naohito Nozaki, Hiroyuki Aburatani, Masaomi Nangaku, Xiaoan Ruan, Hideyuki Tanabe, Yijun Ruan, Sigeo Ihara, Akira Endo, Tatsuhiko Kodama, Youichiro Wada
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e96005 (2014)
Statins exert atheroprotective effects through the induction of specific transcriptional factors in multiple organs. In endothelial cells, statin-dependent atheroprotective gene up-regulation is mediated by Kruppel-like factor (KLF) family transcript
Externí odkaz:
https://doaj.org/article/980738f3096b45cab03bd5e5e3c87937