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Genome-wide Association Identifies Novel Etiological Insights Associated with Parkinson's Disease in African and African Admixed Populations.

Autor: Rizig M; Department of Neuromuscular Diseases, UCL Queen Square Institute of Neurology, London WC1N 3BG, UK.; UCL Movement Disorders Centre, University College London, London, WC1N 3BG, UK., Bandres-Ciga S; Center for Alzheimer's and Related Dementias (CARD), National Institute on Aging and National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA, 20814., Makarious MB; UCL Movement Disorders Centre, University College London, London, WC1N 3BG, UK.; Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, MD, USA., Ojo O; College of Medicine, University of Lagos, Idi Araba, Lagos State, Nigeria., Crea PW; Center for Alzheimer's and Related Dementias (CARD), National Institute on Aging and National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA, 20814.; Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, MD, USA., Abiodun O; General Hospital, Isolo, Lagos State, Nigeria., Levine KS; Center for Alzheimer's and Related Dementias (CARD), National Institute on Aging and National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA, 20814.; Data Tecnica International, Washington, DC, USA., Abubakar S; Ahmadu Bello University, Zaria, Kaduna State, Nigeria., Achoru C; Jos University Teaching Hospital, Jos, Plateau State, Nigeria., Vitale D; Data Tecnica International, Washington, DC, USA., Adeniji O; Federal Medical Centre, Abeokuta, Ogun State, Nigeria., Agabi O; College of Medicine, University of Lagos, Idi Araba, Lagos State, Nigeria., Koretsky MJ; Center for Alzheimer's and Related Dementias (CARD), National Institute on Aging and National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA, 20814., Agulanna U; Lagos University Teaching Hospital, Idi Araba, Lagos State, Nigeria., Hall DA; Department of Neurological Sciences, Rush University Medical Center, Chicago, IL, USA., Akinyemi R; Neuroscience and Ageing Research Unit, Institute for Advanced Medical Research and Training, College of Medicine, University of Ibadan, Ibadan, Oyo State, Nigeria., Xie T; Department of Neurology, University of Chicago Medicine, Chicago, Illinois, USA., Ali M; Federal Teaching Hospital Gombe, Gombe State, Nigeria., Shamim EA; Human Motor Control Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, USA.; Kaiser Permanente Mid-Atlantic States, Largo, Maryland, USA.; MidAtlantic Permanente Research Institute, Rockville, Maryland, USA., Ani-Osheku I; Asokoro District Hospital, Asokoro, Abuja, Nigeria., Padmanaban M; Department of Neurology, University of Chicago Medicine, Chicago, Illinois, USA., Arigbodi O; Delta State University, Abraka, Delta State, Nigeria., Standaert DG; Department of Neurology, University of Alabama at Birmingham, Birmingham, AL, USA., Bello A; University of Ilorin Teaching Hospital, Ilorin, Kwara State, Nigeria., Dean M; Department of Neurology, University of Alabama at Birmingham, Birmingham, AL, USA., Erameh C; Irrua Specialist Teaching Hospital, Irrua, Edo State, Nigeria., Elsayed I; Faculty of Pharmacy, University of Gezira, Wadmadani, 20, Sudan., Farombi T; University College Hospital, Ibadan, Oyo State, Nigeria., Okunoye O; Department of Neuromuscular Diseases, UCL Queen Square Institute of Neurology, London WC1N 3BG, UK., Fawale M; Obafemi Awolowo University, Ile-Ife, Osun State, Nigeria., Billingsley KJ; Center for Alzheimer's and Related Dementias (CARD), National Institute on Aging and National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA, 20814.; Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, MD, USA., Imarhiagbe F; University of Benin, Benin City, Edo State, Nigeria., Jerez PA; Department of Neuromuscular Diseases, UCL Queen Square Institute of Neurology, London WC1N 3BG, UK.; Center for Alzheimer's and Related Dementias (CARD), National Institute on Aging and National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA, 20814., Iwuozo E; Benue State University, Makurdi, Benue State, Nigeria., Baker B; Center for Alzheimer's and Related Dementias (CARD), National Institute on Aging and National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA, 20814., Komolafe M; Obafemi Awolowo University, Ile-Ife, Osun State, Nigeria., Malik L; Center for Alzheimer's and Related Dementias (CARD), National Institute on Aging and National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA, 20814., Nwani P; Nnamdi Azikiwe University Teaching Hospital, Nnewi, Anambra State, Nigeria., Daida K; Center for Alzheimer's and Related Dementias (CARD), National Institute on Aging and National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA, 20814.; Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, MD, USA., Nwazor E; Rivers State University Teaching Hospital, Port Harcourt, Rivers State, Nigeria., Miano-Burkhardt A; Center for Alzheimer's and Related Dementias (CARD), National Institute on Aging and National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA, 20814.; Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, MD, USA., Nyandaiti Y; University of Maiduguri Teaching Hospital, Maiduguri, Borno State, Nigeria., Fang ZH; German Center for Neurodegenerative Diseases (DZNE), Tuebingen, Germany., Obiabo Y; Federal University of Health Sciences, Otukpo, Benue State, Nigeria., Kluss JH; Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, MD, USA., Odeniyi O; General Hospital, Lagos Island, Lagos State, Nigeria., Hernandez D; Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, MD, USA., Odiase F; University of Benin, Benin City, Edo State, Nigeria., Tayebi N; Medical Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, USA., Ojini F; College of Medicine, University of Lagos, Idi Araba, Lagos State, Nigeria., Sidranksy E; Medical Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, USA., Onwuegbuzie G; University of Abuja, Abuja, Federal Capital Territory, Nigeria., D'Souza AM; Medical Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, USA., Osaigbovo G; Jos University Teaching Hospital, Jos, Plateau State, Nigeria., Berhe B; Medical Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, USA., Osemwegie N; University of Port Harcourt, Port Harcourt, Rivers State, Nigeria., Reed X; Center for Alzheimer's and Related Dementias (CARD), National Institute on Aging and National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA, 20814., Oshinaike O; Lagos State University College of Medicine, Ikeja, Lagos State, Nigeria., Leonard H; Center for Alzheimer's and Related Dementias (CARD), National Institute on Aging and National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA, 20814.; Data Tecnica International, Washington, DC, USA., Otubogun F; Federal Medical Center, Ebute Metta, Lagos State, Nigeria., Alvarado CX; Center for Alzheimer's and Related Dementias (CARD), National Institute on Aging and National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA, 20814.; Data Tecnica International, Washington, DC, USA., Oyakhire S; National Hospital, Abuja, Federal Capital Territory, Nigeria., Ozomma S; University of Calabar Teaching Hospital, Calabar, Cross River State, Nigeria., Samuel S; University of Maiduguri Teaching Hospital, Maiduguri, Borno State, Nigeria., Taiwo F; University College Hospital, Ibadan, Oyo State, Nigeria., Wahab K; University of Ilorin Teaching Hospital, Ilorin, Kwara State, Nigeria.; University of Ilorin, Ilorin, Kwara State, Nigeria., Zubair Y; National Hospital, Abuja, Federal Capital Territory, Nigeria., Iwaki H; Center for Alzheimer's and Related Dementias (CARD), National Institute on Aging and National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA, 20814.; Data Tecnica International, Washington, DC, USA., Kim JJ; Center for Alzheimer's and Related Dementias (CARD), National Institute on Aging and National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA, 20814.; Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, MD, USA., Morris HR; Department of Neuromuscular Diseases, UCL Queen Square Institute of Neurology, London WC1N 3BG, UK.; UCL Movement Disorders Centre, University College London, London, WC1N 3BG, UK., Hardy J; Department of Neuromuscular Diseases, UCL Queen Square Institute of Neurology, London WC1N 3BG, UK., Nalls M; Data Tecnica International, Washington, DC, USA., Heilbron K; 23andMe, Inc., Sunnyvale, CA, USA., Norcliffe-Kaufmann L; 23andMe, Inc., Sunnyvale, CA, USA., Blauwendraat C; Center for Alzheimer's and Related Dementias (CARD), National Institute on Aging and National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA, 20814.; Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, MD, USA., Houlden H; Department of Neuromuscular Diseases, UCL Queen Square Institute of Neurology, London WC1N 3BG, UK., Singleton A; Center for Alzheimer's and Related Dementias (CARD), National Institute on Aging and National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA, 20814.; Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, MD, USA., Okubadejo N; College of Medicine, University of Lagos, Idi Araba, Lagos State, Nigeria.

Publikováno v: MedRxiv : the preprint server for health sciences [medRxiv] 2023 May 07. Date of Electronic Publication: 2023 May 07.