An Operant Conditioning Task to Assess the Choice between Wheel Running and Palatable Food in Mice

Autor: Bastien Redon, Imane Hurel, Giovanni Marsicano, Francis Chaouloff

Publikováno v: Bio-Protocol, Vol 9, Iss 19 (2019)

Wheel running, especially in the homecage, has been widely used to study the neurobiology of exercise because animal tends to use it voluntarily. However, as for each reward, its consumption (in the present case, running performance) does not specifi

Externí odkaz: https://doaj.org/article/3e48698a3f6e453eb01617c1bc502641

Exercise craving potentiates excitatory inputs to ventral tegmental area dopaminergic neurons

Autor: Miriam Melis, Bastien Redon, François Georges, Maria-Carmen Medrano, Emma Mesguich, Francis Chaouloff, Christopher Stevens, Imane Hurel, Giovanni Marsicano

Publikováno v: Addiction Biology
Addiction Biology, Wiley, In press, ⟨10.1111/adb.12967⟩
Addiction Biology, In press, ⟨10.1111/adb.12967⟩
Addiction Biology, Wiley, 2020, ⟨10.1111/adb.12967⟩

International audience; Physical exercise, which can be addictogenic on its own, is considered a therapeutic alternative for drug craving. Exercise might thus share with drugs the ability to strengthen excitatory synapses onto ventral tegmental area

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::107e5ae628c954b50b9bb03e88899bdd
https://hal.archives-ouvertes.fr/hal-03129765

The motivation for exercise over palatable food is dictated by cannabinoid type-1 receptors

Autor: Arnau Busquets-Garcia, Giulia R. Fois, Stéphanie Caillé, Edgar Soria-Gomez, Claire Nguyen, Francis Chaouloff, Carolina Muguruza, François Georges, Bastien Redon, Marjorie Varilh, Astrid Cannich, Giovanni Marsicano, Teresa Pelliccia, Imane Hurel, Amandine Scocard, Christopher Stevens, Justine Daniault

Publikováno v: JCI Insight
JCI Insight, American Society for Clinical Investigation, 2019, 4 (5), ⟨10.1172/jci.insight.126190⟩
JCI Insight, American Society for Clinical Investigation, 2019, 4 (5), pp.e126190. ⟨10.1172/jci.insight.126190⟩
JCI Insight, 2019, 4 (5), pp.e126190. ⟨10.1172/jci.insight.126190⟩

International audience; The lack of intrinsic motivation to engage in, and adhere to, physical exercise has major health consequences. However, the neurobiological bases of exercise motivation are still unknown. This study aimed at examining whether

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::613097e89f74acacb36efe615536be60
https://hal.archives-ouvertes.fr/hal-02361338

A paradigm to specifically assess the respective drives for exercise and feeding in a reward-choice test in mice: Influence of adolescent stress

Autor: A. Scocard, Francis Chaouloff, Giovanni Marsicano, B. Redon, Imane Hurel

Publikováno v: Nutrition Clinique et Métabolisme. 34:7

Introduction Anorexia nervosa (AN), mostly observed in female adolescents, is the most fatal mental illness. Its core is a motivational imbalance between exercise and feeding in favour of the former. Although several animal models of AN have been pro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0b7c1c93e74ed258ca25e70f3c9cf016
https://doi.org/10.1016/j.nupar.2020.02.012