Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Iman Mehdizadeh Gohari"'
Publikováno v:
mBio, Vol 15, Iss 4 (2024)
ABSTRACTSporulation is an important feature of the clostridial life cycle, facilitating survival of these bacteria in harsh environments, contributing to disease transmission for pathogenic species, and sharing common early steps that are also involv
Externí odkaz:
https://doaj.org/article/f6775f9742c9444da88ea5260b3adcd2
Publikováno v:
Toxins, Vol 16, Iss 4, p 195 (2024)
The CPR1953 and CPR1954 orphan histidine kinases profoundly affect sporulation initiation and Clostridium perfringens enterotoxin (CPE) production by C. perfringens type F strain SM101, whether cultured in vitro (modified Duncan–Strong sporulation
Externí odkaz:
https://doaj.org/article/da83f87fae7249119c2a77edbf5e1095
Autor:
Iman Mehdizadeh Gohari, Jihong Li, Mauricio A Navarro, Fábio S Mendonça, Francisco A Uzal, Bruce A McClane
Publikováno v:
PLoS Pathogens, Vol 19, Iss 6, p e1011429 (2023)
When causing food poisoning or antibiotic-associated diarrhea, Clostridium perfringens type F strains must sporulate to produce C. perfringens enterotoxin (CPE) in the intestines. C. perfringens is thought to use some of its seven annotated orphan hi
Externí odkaz:
https://doaj.org/article/59ef57e9e6544e14aacf69798b24be1f
Autor:
Iman Mehdizadeh Gohari, Mauricio A. Navarro, Jihong Li, Archana Shrestha, Francisco Uzal, Bruce A. McClane
Publikováno v:
Virulence, Vol 12, Iss 1, Pp 723-753 (2021)
Clostridium perfringens is an extremely versatile pathogen of humans and livestock, causing wound infections like gas gangrene (clostridial myonecrosis), enteritis/enterocolitis (including one of the most common human food-borne illnesses), and enter
Externí odkaz:
https://doaj.org/article/0b7cd7c38fa3466b88220a863919bdb4
Publikováno v:
mBio, Vol 13, Iss 2 (2022)
ABSTRACT Clostridium perfringens type B and D strains produce epsilon-toxin (ETX). Our 2011 mBio study (mBio 2:e00275-11, 2011, https://doi.org/10.1128/mBio.00275-11) reported that the Agr quorum-sensing (QS) system regulates ETX production by type D
Externí odkaz:
https://doaj.org/article/98676a797d0a4a53a7faffa2e4711dda
Autor:
Natalie Sindern, Jan S. Suchodolski, Christian M. Leutenegger, Iman Mehdizadeh Gohari, John F. Prescott, Anna‐Lena Proksch, Ralf S. Mueller, Kathrin Busch, Stefan Unterer
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 33, Iss 1, Pp 100-105 (2019)
Background Recently, novel pore‐forming toxin genes designated netE and netF were identified in a Clostridium perfringens type A strain isolated from a dog with acute hemorrhagic diarrhea. Objectives Pore‐forming toxins could play an important ro
Externí odkaz:
https://doaj.org/article/4ac9bbdb453b4350ae299c7bef6122a9
Publikováno v:
mBio, Vol 10, Iss 6 (2019)
ABSTRACT Clostridium perfringens type F strains cause gastrointestinal disease when they produce a pore-forming toxin named C. perfringens enterotoxin (CPE). In human enterocyte-like Caco-2 cells, low CPE concentrations cause caspase-3-dependent apop
Externí odkaz:
https://doaj.org/article/e5435ed5905e4157a311ebfe2783d3df
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
Externí odkaz:
https://doaj.org/article/117ffcac49b344f19999d75b07763bbf
Autor:
Iman Mehdizadeh Gohari, Eric K Brefo-Mensah, Michael Palmer, Patrick Boerlin, John F Prescott
Publikováno v:
PLoS ONE, Vol 13, Iss 11, p e0206815 (2018)
NetF-producing type A Clostridium perfringens is an important cause of canine and foal necrotizing enteritis. NetF, related to the β-sheet pore-forming Leukocidin/Hemolysin superfamily, is considered a major virulence factor for this disease. The ma
Externí odkaz:
https://doaj.org/article/601ce1b7e6d04d1a8065f19f7e505a07
Publikováno v:
Toxins, Vol 11, Iss 10, p 582 (2019)
Clostridium perfringens enterotoxin (CPE) contributes to diarrhea and an often-lethal enterotoxemia. CPE action starts when it binds to claudin receptors, forming a small complex (90 kDa). Six small complexes then oligomerize to create prepores, foll
Externí odkaz:
https://doaj.org/article/8c9594d75b2f45c4817835e03e321bfe