Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Iman Mali"'
Autor:
Emanuel Gonçalves, Aldo Segura‐Cabrera, Clare Pacini, Gabriele Picco, Fiona M Behan, Patricia Jaaks, Elizabeth A Coker, Donny van der Meer, Andrew Barthorpe, Howard Lightfoot, Tatiana Mironenko, Alexandra Beck, Laura Richardson, Wanjuan Yang, Ermira Lleshi, James Hall, Charlotte Tolley, Caitlin Hall, Iman Mali, Frances Thomas, James Morris, Andrew R Leach, James T Lynch, Ben Sidders, Claire Crafter, Francesco Iorio, Stephen Fawell, Mathew J Garnett
Publikováno v:
Molecular Systems Biology, Vol 16, Iss 7, Pp 1-14 (2020)
Abstract Low success rates during drug development are due, in part, to the difficulty of defining drug mechanism‐of‐action and molecular markers of therapeutic activity. Here, we integrated 199,219 drug sensitivity measurements for 397 unique an
Externí odkaz:
https://doaj.org/article/8d3c7a8706894b218dbc302dbd8ec445
Autor:
Emanuel Gonçalves, Rebecca C Poulos, Zhaoxiang Cai, Syd Barthorpe, Srikanth S Manda, Natasha Lucas, Alexandra Beck, Daniel Bucio-Noble, Michael Dausmann, Caitlin Hall, Michael Hecker, Jennifer Koh, Sadia Mahboob, Iman Mali, James Morris, Laura Richardson, Akila J Seneviratne, Erin Sykes, Frances Thomas, Sara Valentini, Steven G Williams, Yangxiu Wu, Dylan Xavier, Karen L MacKenzie, Peter G Hains, Brett Tully, Phillip J Robinson, Qing Zhong, Mathew J Garnett, Roger R Reddel
SummaryThe proteome provides unique insights into biology and disease beyond the genome and transcriptome. Lack of large proteomic datasets has restricted identification of new cancer biomarkers. Here, proteomes of 949 cancer cell lines across 28 tis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9ab6090375c95783a1345c281a33a98b
https://doi.org/10.1101/2022.02.26.482008
https://doi.org/10.1101/2022.02.26.482008
Autor:
Emanuel Gonçalves, Rebecca C. Poulos, Zhaoxiang Cai, Syd Barthorpe, Srikanth S. Manda, Natasha Lucas, Alexandra Beck, Daniel Bucio-Noble, Michael Dausmann, Caitlin Hall, Michael Hecker, Jennifer Koh, Howard Lightfoot, Sadia Mahboob, Iman Mali, James Morris, Laura Richardson, Akila J. Seneviratne, Rebecca Shepherd, Erin Sykes, Frances Thomas, Sara Valentini, Steven G. Williams, Yangxiu Wu, Dylan Xavier, Karen L. MacKenzie, Peter G. Hains, Brett Tully, Phillip J. Robinson, Qing Zhong, Mathew J. Garnett, Roger R. Reddel
Publikováno v:
Cancer Cell
The proteome provides unique insights into disease biology beyond the genome and transcriptome. A lack of large proteomic datasets has restricted the identification of new cancer biomarkers. Here, proteomes of 949 cancer cell lines across 28 tissue t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b3a20c7e98090d73382989efa0e217c
https://pubmed.ncbi.nlm.nih.gov/35839778
https://pubmed.ncbi.nlm.nih.gov/35839778
This protocol is about Differentiation of hPSCs to hypothalamic neurons.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::50561436d55957ed0d1a15657b72002d
https://doi.org/10.17504/protocols.io.bzghp3t6
https://doi.org/10.17504/protocols.io.bzghp3t6
Autor:
Patricia Jaaks, Elizabeth A. Coker, Daniel J. Vis, Olivia Edwards, Emma F. Carpenter, Simonetta M. Leto, Lisa Dwane, Francesco Sassi, Howard Lightfoot, Syd Barthorpe, Dieudonne van der Meer, Wanjuan Yang, Alexandra Beck, Tatiana Mironenko, Caitlin Hall, James Hall, Iman Mali, Laura Richardson, Charlotte Tolley, James Morris, Frances Thomas, Ermira Lleshi, Nanne Aben, Cyril H. Benes, Andrea Bertotti, Livio Trusolino, Lodewyk Wessels, Mathew J. Garnett
Publikováno v:
NATURE
Nature: international weekly journal of science, 603(7899)
Nature: international weekly journal of science, 603(7899)
Combinations of anti-cancer drugs can overcome resistance and provide new treatments1,2. The number of possible drug combinations vastly exceeds what could be tested clinically. Efforts to systematically identify active combinations and the tissues a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99fc1884fa3d13b5a34231b13ffdc860
https://pubmed.ncbi.nlm.nih.gov/35197630
https://pubmed.ncbi.nlm.nih.gov/35197630
This protocol is about Differentiation of hPSCs to hypothalamic neurons.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::96e221d86bfd16f47facc8d276e2a2f7
https://doi.org/10.17504/protocols.io.bn8qmhvw
https://doi.org/10.17504/protocols.io.bn8qmhvw
Autor:
Gabriele Picco, Stephen Fawell, Ben Sidders, Andrew Barthorpe, Clare Pacini, Elizabeth A. Coker, Andrew R. Leach, Francesco Iorio, Laura Richardson, Caitlin Hall, Claire Crafter, Alexandra Beck, James T. Lynch, Charlotte Tolley, Mathew J. Garnett, Iman Mali, James Hall, Donny van der Meer, Wanjuan Yang, James Morris, Ermira Lleshi, Patricia Jaaks, Aldo Segura-Cabrera, Howard Lightfoot, Emanuel Gonçalves, Fiona M. Behan, Tatiana Mironenko, Frances Thomas
Publikováno v:
Molecular Systems Biology, Vol 16, Iss 7, Pp n/a-n/a (2020)
Low success rates during drug development are due, in part, to the difficulty of defining drug mechanism‐of‐action and molecular markers of therapeutic activity. Here, we integrated 199,219 drug sensitivity measurements for 397 unique anti‐canc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e2859299eef5fc39e0f58493173321d
https://doi.org/10.15252/msb.20199405
https://doi.org/10.15252/msb.20199405