Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Iman M. Hu"'
Autor:
Alessandra Tammaro, Eileen G. Daniels, Iman M. Hu, Kelly C. ‘t Hart, Kim Reid, Rio P. Juni, Loes M. Butter, Goutham Vasam, Rashmi Kamble, Aldo Jongejan, Richard I. Aviv, Joris J.T.H. Roelofs, Eleonora Aronica, Reinier A. Boon, Keir J. Menzies, Riekelt H. Houtkooper, Georges E. Janssens
Publikováno v:
iScience, Vol 27, Iss 1, Pp 108681- (2024)
Summary: Aging increases the risk of age-related diseases, imposing substantial healthcare and personal costs. Targeting fundamental aging mechanisms pharmacologically can promote healthy aging and reduce this disease susceptibility. In this work, we
Externí odkaz:
https://doaj.org/article/42cc145abf8d478f88355c37c49e69d9
Reducing mitochondrial ribosomal gene expression does not alter metabolic health or lifespan in mice
Autor:
Kim Reid, Eileen G. Daniels, Goutham Vasam, Rashmi Kamble, Georges E. Janssens, Iman M. Hu, Alexander E. Green, Riekelt H. Houtkooper, Keir J. Menzies
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Maintaining mitochondrial function is critical to an improved healthspan and lifespan. Introducing mild stress by inhibiting mitochondrial translation invokes the mitochondrial unfolded protein response (UPRmt) and increases lifespan in seve
Externí odkaz:
https://doaj.org/article/04f22427ca1c4e4aba80208d5951efcd