Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Imaging transcriptomics"'
Autor:
Yuanhao Li, Su Yan, Jia Li, Yuanyuan Qin, Li Li, Nanxi Shen, Yan Xie, Dong Liu, Jicheng Fang, Tian Tian, Wenzhen Zhu
Publikováno v:
BMC Psychiatry, Vol 24, Iss 1, Pp 1-12 (2024)
Abstract Objective State anxiety and trait anxiety are differentially mapped in brain function. However, the genetic and neurobiological basis of anxiety-related functional changes remain largely unknown. Methods Participants aged 18–30 from the co
Externí odkaz:
https://doaj.org/article/150c9dd67d794f8090ce6b5cc300c22d
Autor:
Zhipeng Cao, Guilai Zhan, Jinmei Qin, Renata B. Cupertino, Jonatan Ottino-Gonzalez, Alistair Murphy, Devarshi Pancholi, Sage Hahn, Dekang Yuan, Peter Callas, Scott Mackey, Hugh Garavan
Publikováno v:
NeuroImage, Vol 293, Iss , Pp 120622- (2024)
Correlating transcriptional profiles with imaging-derived phenotypes has the potential to reveal possible molecular architectures associated with cognitive functions, brain development and disorders. Competitive null models built by resampling genes
Externí odkaz:
https://doaj.org/article/5bf238024c144747b095adb721d50a2a
Autor:
Shelli R. Kesler, Rebecca A. Harrison, Alexa De La Torre Schutz, Hayley Michener, Paris Bean, Veronica Vallone, Sarah Prinsloo
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
IntroductionLike other forms of neuropathology, gliomas appear to spread along neural pathways. Accordingly, our group and others have previously shown that brain network connectivity is highly predictive of glioma survival. In this study, we aimed t
Externí odkaz:
https://doaj.org/article/69501d91af0049398119f3da94e17c18
Autor:
Veronika Pak, Quadri Adewale, Danilo Bzdok, Mahsa Dadar, Yashar Zeighami, Yasser Iturria-Medina
Publikováno v:
eLife, Vol 12 (2024)
For over a century, brain research narrative has mainly centered on neuron cells. Accordingly, most neurodegenerative studies focus on neuronal dysfunction and their selective vulnerability, while we lack comprehensive analyses of other major cell ty
Externí odkaz:
https://doaj.org/article/c91a0051471f4d7aa892e4c6b81ff5ff
Autor:
Marvin Petersen, Felix Hoffstaedter, Felix L Nägele, Carola Mayer, Maximilian Schell, D Leander Rimmele, Birgit-Christiane Zyriax, Tanja Zeller, Simone Kühn, Jürgen Gallinat, Jens Fiehler, Raphael Twerenbold, Amir Omidvarnia, Kaustubh R Patil, Simon B Eickhoff, Goetz Thomalla, Bastian Cheng
Publikováno v:
eLife, Vol 12 (2024)
The link between metabolic syndrome (MetS) and neurodegenerative as well as cerebrovascular conditions holds substantial implications for brain health in at-risk populations. This study elucidates the complex relationship between MetS and brain healt
Externí odkaz:
https://doaj.org/article/e24a4af5d92b4603a3b15652a7e45911
Autor:
Iris J. Broce, Daniel W. Sirkis, Ryan M. Nillo, Luke W. Bonham, Suzee E. Lee, Bruce L. Miller, Patricia A. Castruita, Virginia E. Sturm, Leo S. Sugrue, Rahul S. Desikan, Jennifer S. Yokoyama
Publikováno v:
Frontiers in Neuroscience, Vol 18 (2024)
IntroductionA hexanucleotide repeat expansion (HRE) intronic to chromosome 9 open reading frame 72 (C9orf72) is recognized as the most common genetic cause of amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD), and ALS-FTD. Identifyin
Externí odkaz:
https://doaj.org/article/b13a9c462df547a2b3c345568ced924f
Autor:
Isabel Kerrebijn, Michael Wainberg, Peter Zhukovsky, Yuxiao Chen, Melanie Davie, Daniel Felsky, Shreejoy J. Tripathy
Publikováno v:
NeuroImage, Vol 276, Iss , Pp 120177- (2023)
Many neuropsychiatric disorders are characterised by altered cortical thickness, but the cell types underlying these changes remain largely unknown. Virtual histology (VH) approaches map regional patterns of gene expression with regional patterns of
Externí odkaz:
https://doaj.org/article/a3303179fffc4c95867b03fb767c1313
Akademický článek
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Autor:
Flavia Venetucci Gouveia, Jurgen Germann, Gavin JB Elias, Alexandre Boutet, Aaron Loh, Adriana Lucia Lopez Rios, Cristina Torres Diaz, William Omar Contreras Lopez, Raquel Chacon Ruiz Martinez, Erich Talamoni Fonoff, Juan Carlos Benedetti-Isaac, Peter Giacobbe, Pablo M Arango Pava, Han Yan, George M Ibrahim, Nir Lipsman, Andres Lozano, Clement Hamani
Publikováno v:
eLife, Vol 12 (2023)
Deep brain stimulation targeting the posterior hypothalamus (pHyp-DBS) is being investigated as a treatment for refractory aggressive behavior, but its mechanisms of action remain elusive. We conducted an integrated imaging analysis of a large multi-
Externí odkaz:
https://doaj.org/article/4a1930d7fc5c47beb53ea4d7a0f5d818
Autor:
Jae Young Baik, Mansu Kim, Jingxuan Bao, Qi Long, Li Shen, Alzheimer’s Disease Neuroimaging Initiative
Publikováno v:
BMC Medical Genomics, Vol 15, Iss S2, Pp 1-11 (2022)
Abstract Background Alzheimer’s disease (AD) is one of the most common neurodegenerative disorders characterized by progressive decline in cognitive function. Targeted genetic analyses, genome-wide association studies, and imaging genetic analyses
Externí odkaz:
https://doaj.org/article/9b19b4ad417548069066a675fde755dc