Zobrazeno 1 - 10
of 423
pro vyhledávání: '"Imaging mass cytometry"'
Autor:
Ole Vidhammer Bjørnstad, Manuel Carrasco, Kenneth Finne, Vandana Ardawatia, Ingeborg Winge, Cecilie Askeland, Jarle B. Arnes, Gøril Knutsvik, Dimitrios Kleftogiannis, Joao A. Paulo, Lars A. Akslen, Heidrun Vethe
Publikováno v:
EBioMedicine, Vol 108, Iss , Pp 105325- (2024)
Summary: Background: Presence of nerves in tumours, by axonogenesis and neurogenesis, is gaining increased attention for its impact on cancer initiation and development, and the new field of cancer neuroscience is emerging. A recent study in prostate
Externí odkaz:
https://doaj.org/article/b4465446dd87464692b1cff514237eab
Autor:
Harshavardhan Lingegowda, Katherine B Zutautas, Yuhong Wei, Priyanka Yolmo, Danielle J Sisnett, Alison McCallion, Madhuri Koti, Chandrakant Tayade
Publikováno v:
eLife, Vol 13 (2024)
Endometriosis (EM), characterized by the presence of endometrial-like tissue outside the uterus, is the leading cause of chronic pelvic pain and infertility in females of reproductive age. Despite its high prevalence, the molecular mechanisms underly
Externí odkaz:
https://doaj.org/article/c48ed1b6e15c42d6aae78e398a31a17c
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Immune-related skin diseases represent a collective of dermatological disorders intricately linked to dysfunctional immune system processes. These conditions are primarily characterized by an immoderate activation of the immune system or deviant immu
Externí odkaz:
https://doaj.org/article/88bc25664f80474d84656efe8b36a1ba
Autor:
Stian Tornaas, Dimitrios Kleftogiannis, Siren Fromreide, Hilde Ytre-Hauge Smeland, Hans Jørgen Aarstad, Olav Karsten Vintermyr, Lars Andreas Akslen, Daniela Elena Costea, Harsh Nitin Dongre
Publikováno v:
Heliyon, Vol 10, Iss 10, Pp e31191- (2024)
To decipher the interactions between various components of the tumor microenvironment (TME) and tumor cells in a preserved spatial context, a multiparametric approach is essential. In this pursuit, imaging mass cytometry (IMC) emerges as a valuable t
Externí odkaz:
https://doaj.org/article/6344f46aeae6447b80fe879f9f1b0eb1
Publikováno v:
BMC Bioinformatics, Vol 25, Iss 1, Pp 1-8 (2024)
Abstract Background Highly multiplexed imaging enables single-cell-resolved detection of numerous biological molecules in their spatial tissue context. Interactive visualization of multiplexed imaging data is crucial at any step of data analysis to f
Externí odkaz:
https://doaj.org/article/2c7a9adba09d4aaea9f35459784eb874
Autor:
Patrice Hemon, Danivanh Ben-Guigui, Margaux Geier, Marine Castillon, Corentin Paranthoen, Jacques-Olivier Pers, Marion Le Rochais, Arnaud Uguen
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Imaging mass cytometry (IMC) is a metal mass spectrometry-based method allowing highly multiplex immunophenotyping of cells within tissue samples. However, some limitations of IMC are its 1-µm resolution and its time and costs of analysis limiting r
Externí odkaz:
https://doaj.org/article/c49875d7ccd44e5dba79f916f2eee806
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Imaging Mass Cytometry (IMC) is a novel, and formidable high multiplexing imaging method emerging as a promising tool for in-depth studying of tissue architecture and intercellular communications. Several studies have reported various IMC antibody pa
Externí odkaz:
https://doaj.org/article/0a6ea3cf4f84423c9baffcffbe22473b
Autor:
Sophie M. Pearce, Neil A. Cross, David P. Smith, Malcolm R. Clench, Lucy E. Flint, Gregory Hamm, Richard Goodwin, James I. Langridge, Emmanuelle Claude, Laura M. Cole
Publikováno v:
Metabolites, Vol 14, Iss 6, p 315 (2024)
A multimodal mass spectrometry imaging (MSI) approach was used to investigate the chemotherapy drug-induced response of a Multicellular Tumour Spheroid (MCTS) 3D cell culture model of osteosarcoma (OS). The work addresses the critical demand for enha
Externí odkaz:
https://doaj.org/article/33234cee908948bdb3d0d0201de8eb8b
Autor:
Luke Milross, Bethany Hunter, David McDonald, George Merces, Amanda Thomson, Catharien M.U. Hilkens, John Wills, Paul Rees, Kasim Jiwa, Nigel Cooper, Joaquim Majo, Helen Ashwin, Christopher J.A. Duncan, Paul M. Kaye, Omer Ali Bayraktar, Andrew Filby, Andrew J. Fisher
Publikováno v:
EBioMedicine, Vol 99, Iss , Pp 104945- (2024)
Summary: Background: Lung damage in severe COVID-19 is highly heterogeneous however studies with dedicated spatial distinction of discrete temporal phases of diffuse alveolar damage (DAD) and alternate lung injury patterns are lacking. Existing studi
Externí odkaz:
https://doaj.org/article/1b7f1a779bc24e5da70f8643842a6531
Autor:
Sanique M. South, M. Caleb Marlin, Padmaja Mehta-D'souza, Tayte Stephens, Taylor Conner, Kevin G. Burt, Joel M. Guthridge, Carla R. Scanzello, Timothy M. Griffin
Publikováno v:
Osteoarthritis and Cartilage Open, Vol 5, Iss 4, Pp 100416- (2023)
Objective: To develop an imaging mass cytometry method for identifying complex cell phenotypes, inter-cellular interactions, and population changes in the synovium and infrapatellar fat pad (IFP) of the mouse knee following a non-invasive compression
Externí odkaz:
https://doaj.org/article/9a6f8243865347f88ebe2d1ff564dc09