A lymphatic-absorbed multi-targeted kinase inhibitor for myelofibrosis therapy.

Autor: Ross BD; Department of Radiology and the Center for Molecular Imaging, University of Michigan School of Medicine, Ann Arbor, MI, USA. bdross@umich.edu.; Department of Biological Chemistry, University of Michigan School of Medicine, Ann Arbor, MI, USA. bdross@umich.edu., Jang Y; Department of Radiology and the Center for Molecular Imaging, University of Michigan School of Medicine, Ann Arbor, MI, USA., Welton A; Department of Radiology and the Center for Molecular Imaging, University of Michigan School of Medicine, Ann Arbor, MI, USA., Bonham CA; Department of Radiology and the Center for Molecular Imaging, University of Michigan School of Medicine, Ann Arbor, MI, USA., Palagama DSW; Department of Radiology and the Center for Molecular Imaging, University of Michigan School of Medicine, Ann Arbor, MI, USA., Heist K; Department of Radiology and the Center for Molecular Imaging, University of Michigan School of Medicine, Ann Arbor, MI, USA., Boppisetti J; Department of Radiology and the Center for Molecular Imaging, University of Michigan School of Medicine, Ann Arbor, MI, USA., Imaduwage KP; Department of Radiology and the Center for Molecular Imaging, University of Michigan School of Medicine, Ann Arbor, MI, USA., Robison T; Department of Radiology and the Center for Molecular Imaging, University of Michigan School of Medicine, Ann Arbor, MI, USA.; Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI, USA., King LR; Department of Radiology and the Center for Molecular Imaging, University of Michigan School of Medicine, Ann Arbor, MI, USA., Zhang EZ; Department of Radiology and the Center for Molecular Imaging, University of Michigan School of Medicine, Ann Arbor, MI, USA., Amirfazli C; Department of Radiology and the Center for Molecular Imaging, University of Michigan School of Medicine, Ann Arbor, MI, USA., Luker KE; Department of Radiology and the Center for Molecular Imaging, University of Michigan School of Medicine, Ann Arbor, MI, USA., Lee WY; Department of Pathology, University of Michigan School of Medicine, Ann Arbor, MI, USA., Luker GD; Department of Radiology and the Center for Molecular Imaging, University of Michigan School of Medicine, Ann Arbor, MI, USA.; Department of Microbiology and Immunology, University of Michigan School of Medicine, Ann Arbor, MI, USA., Chenevert TL; Department of Radiology and the Center for Molecular Imaging, University of Michigan School of Medicine, Ann Arbor, MI, USA., Van Dort ME; Department of Radiology and the Center for Molecular Imaging, University of Michigan School of Medicine, Ann Arbor, MI, USA.

Publikováno v: Nature communications [Nat Commun] 2022 Aug 17; Vol. 13 (1), pp. 4730. Date of Electronic Publication: 2022 Aug 17.

HAMS: High-Affinity Mass Spectrometry Screening. A High-Throughput Screening Method for Identifying the Tightest-Binding Lead Compounds for Target Proteins with No False Positive Identifications.

Autor: Imaduwage KP; The Ralph N. Adams Institute for Bioanalytical Chemistry and Department of Chemistry, University of Kansas, 2030 Becker Drive, Lawrence, KS, 66047, USA., Go EP; The Ralph N. Adams Institute for Bioanalytical Chemistry and Department of Chemistry, University of Kansas, 2030 Becker Drive, Lawrence, KS, 66047, USA., Zhu Z; The Ralph N. Adams Institute for Bioanalytical Chemistry and Department of Chemistry, University of Kansas, 2030 Becker Drive, Lawrence, KS, 66047, USA., Desaire H; The Ralph N. Adams Institute for Bioanalytical Chemistry and Department of Chemistry, University of Kansas, 2030 Becker Drive, Lawrence, KS, 66047, USA. hdesaire@ku.edu.

Publikováno v: Journal of the American Society for Mass Spectrometry [J Am Soc Mass Spectrom] 2016 Nov; Vol. 27 (11), pp. 1870-1877. Date of Electronic Publication: 2016 Sep 06.