Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Imad Libbus"'
Cardiopulmonary nerve stimulation as a novel therapy for cardiac autonomic nervous system modulation
Autor:
Siamak Salavatian, Julio C. Spinelli, Jeremy A. Schaefer, Imad Libbus, Aman Mahajan, J. Andrew Armour
Publikováno v:
Frontiers in Neuroscience, Vol 18 (2024)
Externí odkaz:
https://doaj.org/article/981a05ca8a004f619b05d7f3c34f4cae
Autor:
Imad Libbus, Scott R. Stubbs, Scott T. Mazar, Scott Mindrebo, Bruce H. KenKnight, Lorenzo A. DiCarlo
Publikováno v:
Bioelectronic Medicine, Vol 7, Iss 1, Pp 1-4 (2021)
Abstract Background Vagus Nerve Stimulation (VNS) delivers Autonomic Regulation Therapy (ART) for heart failure (HF), and has been associated with improvement in cardiac function and heart failure symptoms. VNS is delivered using an implantable pulse
Externí odkaz:
https://doaj.org/article/c1e3629e7b7542b99a81e366d3ddb034
Autor:
Marvin A. Konstam, Douglas L. Mann, John James E. Udelson, Jeffrey L. Ardell, Gaetano M. De Ferrari, Martin R. Cowie, Helmut U. Klein, Douglas D. Gregory, Joseph M. Massaro, Imad Libbus, Lorenzo A. DiCarlo, Javed Butler, John D. Parker, John R. Teerlink
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
The ANTHEM-HF, INOVATE-HF, and NECTAR-HF clinical studies of autonomic regulation therapy (ART) using vagus nerve stimulation (VNS) systems have collectively provided dose-ranging information enabling the development of several working hypotheses on
Externí odkaz:
https://doaj.org/article/37261ad1dfdd46dd89f0b8fe3cd990cf
Autor:
Imad Libbus, Rajendra K. Premchand, Kamal Sharma, Sanjay Mittal, Rufino Monteiro, Badri Amurthur, Bruce H. KenKnight, Lorenzo A. DiCarlo, Inder S. Anand
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
IntroductionAlthough heart failure (HF) outcomes have improved dramatically with the use of guideline directed medical therapy and implantable devices, the overall prognosis of patients with HF and reduced ejection fraction (HFrEF) remains poor. Auto
Externí odkaz:
https://doaj.org/article/a33e9eb1e5b441fa871c7eee15cce441
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Heart failure with reduced left ventricular ejection fraction is a progressive disease that claims > 352,000 lives annually in the United States alone. Despite the development of an extensive array of pharmacologic and device therapies, prognosis rem
Externí odkaz:
https://doaj.org/article/1a9db06bc7b746298995c4846c736519
Autor:
Inder S. Anand, Marvin A. Konstam, Helmut U. Klein, Douglas L. Mann, Jeffrey L. Ardell, Douglas D. Gregory, Joseph M. Massaro, Imad Libbus, Lorenzo A. DiCarlo, John James E. Udelson, Javed Butler, John D. Parker, John R. Teerlink
Publikováno v:
ESC Heart Failure, Vol 7, Iss 1, Pp 76-84 (2020)
Abstract Aims Clinical studies of vagal nerve stimulation (VNS) for heart failure with reduced ejection fraction have had mixed results to date. We sought to compare VNS delivery and associated changes in symptoms and function in autonomic regulation
Externí odkaz:
https://doaj.org/article/8223a1ad069d473ea44f4818bf03a6ce
Autor:
Enea Dede, Douglas D. Gregory, Jeffrey L. Ardell, Imad Libbus, Lorenzo A. DiCarlo, Rajendra K. Premchand, Kamal Sharma, Sanjay Mittal, Rufino Monteiro, Inder S. Anand, Hans-Dirk Düngen
Publikováno v:
International Journal of Cardiology: Heart & Vasculature, Vol 37, Iss , Pp 100888- (2021)
Background: The effect of beta-blockade (BB) on response to vagus nerve stimulation (VNS) has not been reported in patients with heart failure and reduced ejection fraction (HFrEF). In the ANTHEM-HF Study, 60 patients received chronic cervical VNS. B
Externí odkaz:
https://doaj.org/article/14ddddf20f1e48f4948b67e3058e4cf4
Autor:
Rajendra K. Premchand, Kamal Sharma, Sanjay Mittal, Rufino Monteiro, Imad Libbus, Jeffrey L. Ardell, Douglas D. Gregory, Bruce H. KenKnight, Badri Amurthur, Lorenzo A. DiCarlo, Inder S. Anand
Publikováno v:
ESC Heart Failure, Vol 6, Iss 5, Pp 1052-1056 (2019)
Abstract Aims Clinical trials of new heart failure (HF) therapies administer guideline‐directed medical therapy (GDMT) as background pharmacologic treatment (BPT). In the ANTHEM‐HF Pilot Study, addition of autonomic regulation therapy to GDMT sig
Externí odkaz:
https://doaj.org/article/7b5ddda00381445686ab8bc9246aae33
Autor:
Inder Anand, Jeffrey L. Ardell, Doug Gregory, Imad Libbus, Lorenzo DiCarlo, Rajendra K. Premchand, Kamal Sharma, Sanjay Mittal, Rufino Monteiro
Publikováno v:
International Journal of Cardiology: Heart & Vasculature, Vol 29, Iss , Pp 100520- (2020)
Background: Recent heart failure studies have associated lower baseline natriuretic peptide levels with improved morbidity/mortality outcomes during pharmaceutical treatment, and better clinical outcomes during neuromodulation (NM) with carotid nerve
Externí odkaz:
https://doaj.org/article/d80b0abe751341aa99fffc022c97a9a4
Autor:
Elizabeth M. Annoni, Dusty Van Helden, Yugene Guo, Brett Levac, Imad Libbus, Bruce H. KenKnight, John W. Osborn, Elena G. Tolkacheva
Publikováno v:
Frontiers in Physiology, Vol 10 (2019)
Chronic hypertension (HTN) affects more than 1 billion people worldwide, and is associated with an increased risk of cardiovascular disease. Despite decades of promising research, effective treatment of HTN remains challenging. This work investigates
Externí odkaz:
https://doaj.org/article/4e1592e53b85405dad49eccec3eef4b2