Zobrazeno 1 - 10
of 300
pro vyhledávání: '"Imad, Najm"'
Autor:
Christian M. Boßelmann, Costin Leu, Tobias Brünger, Lucas Hoffmann, Sara Baldassari, Mathilde Chipaux, Roland Coras, Katja Kobow, Hajo Hamer, Daniel Delev, Karl Rössler, Christian G. Bien, Thilo Kalbhenn, Tom Pieper, Till Hartlieb, Kerstin Becker, Lisa Ferguson, Robyn M. Busch, Stéphanie Baulac, Peter Nürnberg, Imad Najm, Ingmar Blümcke, Dennis Lal
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-10 (2024)
Abstract Lesional focal epilepsy (LFE) is a common and severe seizure disorder caused by epileptogenic lesions, including malformations of cortical development (MCD) and low-grade epilepsy-associated tumors (LEAT). Understanding the genetic etiology
Externí odkaz:
https://doaj.org/article/70232dfff20a4c2b91b969f5ee771baa
Autor:
Elizabeth Spurgeon, Robert Saper, Andreas Alexopoulos, Jane B. Allendorfer, Judith Bar, Jessica Caldwell, Mackenzie Cervenka, Sandra Darling, Stephen Dombrowski, Lisa Gallagher, Sara Lazar, Erik Modlo, Jim Perko, Martha Sajatovic, Bikat Tilahun, Nandan Yardi, Imad Najm
Publikováno v:
Epilepsia Open, Vol 9, Iss 5, Pp 1981-1996 (2024)
Abstract Lifestyle interventions are strategies used to self‐manage medical conditions, such as epilepsy, and often complement traditional pharmacologic and surgical therapies. The need for integrating evidence‐based lifestyle interventions into
Externí odkaz:
https://doaj.org/article/82e84c18faa24d90b5ff93d5bffba5cd
Autor:
Sara Taylor, Seerat Sachdeva, Sandra Darling, Kayela Arrotta, Lisa Gallagher, Alexis Supan, Gabrielle Shipta, Jim Perko, Judi Bar, Joe James, Iris Petschek, Anthony Lioi, Suman Kundu, Lisa Ellison, Lynn M. Bekris, Belinda Willard, Naseer Sangwan, Ignacio Mata, Hubert Fernandez, Irene Katzan, Devon Conway, Jagan Pillai, James Leverenz, Robyn M. Busch, Darlene Floden, Robert Saper, John Barnard, Andre Machado, Imad Najm, Vineet Punia
Publikováno v:
Neurological Research and Practice, Vol 6, Iss 1, Pp 1-9 (2024)
Abstract Introduction Given the prevalence and staggering cost of neurological disorders, there is dire need for effective early detection and intervention tools. Emerging evidence suggests that multidisciplinary lifestyle interventions (MLI) may mit
Externí odkaz:
https://doaj.org/article/d098fa6f801b42dfb525f8e5974a3bf3
Autor:
Shreya Louis, Robyn M. Busch, Dennis Lal, Jennifer Hockings, Olivia Hogue, Marcia Morita-Sherman, Deborah Vegh, Imad Najm, Chaitali Ghosh, Peter Bazeley, Charis Eng, Lara Jehi, Daniel M. Rotroff
Publikováno v:
Frontiers in Neurology, Vol 13 (2022)
ObjectiveSeizure outcomes after brain surgery for drug-resistant epilepsy (DRE) are very heterogeneous and difficult to predict with models utilizing the current clinical, imaging, and electrophysiological variables. In this pilot study, we investiga
Externí odkaz:
https://doaj.org/article/0923aa6f1e3e456bb3380cdefb1c553a
Autor:
Javier A. López-Rivera, Victoria Smuk, Costin Leu, Gaelle Nasr, Deborah Vegh, Arthur Stefanski, Eduardo Pérez-Palma, Robyn Busch, Lara Jehi, Imad Najm, Ingmar Blümcke, Dennis Lal
Publikováno v:
Epilepsy & Behavior Reports, Vol 18, Iss , Pp 100527- (2022)
Epilepsy surgery is an effective treatment option for drug-resistant focal epilepsy patients with associated structural brain lesions. However, little epidemiological data are available regarding the number of patients with these lesions. We reviewed
Externí odkaz:
https://doaj.org/article/c8a6b356c3334f9fba6efd403a6190f7
Autor:
Liri Jin, Joon Yul Choi, Juan Bulacio, Andreas V. Alexopoulos, Richard C. Burgess, Hiroatsu Murakami, William Bingaman, Imad Najm, Zhong Irene Wang
Publikováno v:
Frontiers in Neurology, Vol 12 (2021)
Multimodal image integration (MMII) is a promising tool to help delineate the epileptogenic zone (EZ) in patients with medically intractable focal epilepsies undergoing presurgical evaluation. We report here the detailed methodology of MMII and an ov
Externí odkaz:
https://doaj.org/article/c2a7ddee700648c09cf57bac148fe9b6
Autor:
Vineet Punia, James Bena, Jorge Gonzalez‐Martinez, William Bingaman, Imad Najm, Andrey Stojic, Richard Prayson
Publikováno v:
Epilepsia Open, Vol 4, Iss 2, Pp 328-333 (2019)
Summary Patients 60 years or older are one of the highest risk age groups for development of epilepsy. Clinical and neuroimaging analysis has typically accounted for etiology in two‐thirds of these patients, while the data on histopathology are lac
Externí odkaz:
https://doaj.org/article/15e1cfb2342840748b9a27f437728189
Autor:
Balu Krishnan, Simon Tousseyn, Chetan Sateesh Nayak, Thandar Aung, Ammar Kheder, Z. Irene Wang, Guiyun Wu, Jorge Gonzalez-Martinez, Dileep Nair, Richard Burgess, Leonidas Iasemidis, Imad Najm, Juan Bulacio, Andreas V. Alexopoulos
Publikováno v:
NeuroImage, Vol 231, Iss , Pp 117838- (2021)
Perfusion patterns observed in Subtraction Ictal SPECT Co-registered to MRI (SISCOM) assist in focus localization and surgical planning for patients with medically intractable focal epilepsy. While the localizing value of SISCOM has been widely inves
Externí odkaz:
https://doaj.org/article/ece778e8228d4ebba6f32d4f9bcdf01c
Autor:
Z. Irene Wang, Se-Hong Oh, Mark Lowe, Mykol Larvie, Paul Ruggieri, Virginia Hill, Volodymyr Statsevych, Doksu Moon, Jonathan Lee, Todd Emch, James Bena, Ingmar Blümcke, William Bingaman, Jorge A. Gonzalez-Martinez, Imad Najm, Stephen E. Jones
Publikováno v:
Frontiers in Neurology, Vol 12 (2021)
Objective: The recent FDA approval of the first 7T MRI scanner for clinical diagnostic use in October 2017 will likely increase the utilization of 7T for epilepsy presurgical evaluation. This study aims at accessing the radiological and clinical valu
Externí odkaz:
https://doaj.org/article/f5e1af4d55994fcba9dd938b5c073d64
Autor:
Lucas Hoffmann, Roland Coras, Katja Kobow, Javier A. López-Rivera, Dennis Lal, Costin Leu, Imad Najm, Peter Nürnberg, Jochen Herms, Patrick N. Harter, Christian G. Bien, Thilo Kalbhenn, Markus Müller, Tom Pieper, Till Hartlieb, Manfred Kudernatsch, Hajo Hamer, Sebastian Brandner, Karl Rössler, Ingmar Blümcke, Samir Jabari
Publikováno v:
Acta Neuropathologica. 145:815-827
Exome-wide sequencing studies recently described PTPN11 as a novel brain somatic epilepsy gene. In contrast, germline mutations of PTPN11 are known to cause Noonan syndrome, a multisystem disorder characterized by abnormal facial features, developmen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6d6b418e8446fc02178c4ee9db7301f
https://doi.org/10.1007/s00401-023-02561-5
https://doi.org/10.1007/s00401-023-02561-5