Zobrazeno 1 - 10 of 77 pro vyhledávání: '"Im, Katona"'
1
Phosphatidylinositol-3-kinase activity is required for the anti-ig- mediated growth inhibition of a human B-lymphoma cell line
Autor: M Beckwith, RG Fenton, IM Katona, DL Longo
Publikováno v: Blood. 87:202-210
Stimulation of B lymphocytes through the Ig receptor initiates a cascade of biochemical changes, which can ultimately lead to either activation and growth, or cell-cycle arrest and cell death. One of the critical events that occurs in both cases is t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d0583af972760e05a1d8549ba63d25c9
https://doi.org/10.1182/blood.v87.1.202.bloodjournal871202
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2
IL-4 treatment can cure established gastrointestinal nematode infections in immunocompetent and immunodeficient mice
Autor: Joseph Urban, Cr, Maliszewski, Kb, Madden, Im, Katona, Fd, Finkelman
Publikováno v: Europe PubMed Central
We examined the ability of a long acting formulation of IL-4 (IL-4/anti-IL-4 mAb complexes) to limit established infections of normal and immune deficient mice with two nematode parasites: Heligmosomoides polygyrus and Nippostrongylus brasiliensis. I
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::ff2139df06712faa23ff199165643203
https://pubmed.ncbi.nlm.nih.gov/7722320
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3
IFN inhibits inflammatory responses and protective immunity in mice infected with the nematode parasite, Nippostrongylus brasiliensis
Autor: Joseph Urban, Kb, Madden, Aw, Cheever, Pp, Trotta, Im, Katona, Fd, Finkelman
Publikováno v: Europe PubMed Central
Mice infected with the gastrointestinal nematode parasite Nippostrongylus brasiliensis (Nb) develop responses associated with enhanced production of IL-4 (increased serum IgE levels and intestinal mucosal mastocytosis) and IL-5 (tissue and peripheral
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::df710e5c954cc76b2eb8451c8f4673be
https://pubmed.ncbi.nlm.nih.gov/8258713
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4
The role of L3T4+ and Lyt-2+ T cells in the IgE response and immunity to Nippostrongylus brasiliensis
Autor: Im, Katona, Joseph Urban, Fd, Finkelman
Publikováno v: Europe PubMed Central
The role of L3T4+ and Lyt-2+ T cells in protective immunity to Nippostrongylus brasiliensis (Nb) was studied in BALB/c mice that were depleted of either the L3T4+ or Lyt-2+ T cell population by injection with rat mAb specific for the appropriate dete
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::59716f2171d314cc81b5d94608f915ab
https://pubmed.ncbi.nlm.nih.gov/2966208
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6
T help requirements for the generation of an in vivo IgE response: a late acting form of T cell help other than IL-4 is required for IgE but not for IgG1 production
Autor: Fd, Finkelman, Holmes J, Joseph Urban, We, Paul, Im, Katona
Publikováno v: Europe PubMed Central
To further define requirements for T cell help in the stimulation of an in vivo IgE response, we studied a system in which the injection of mice with a goat antibody to mouse IgD (GaMD) stimulates large polyclonal IgG1 and IgE responses. In this syst
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::04fbc74e6db7f6bed3c197b1504aa833
https://pubmed.ncbi.nlm.nih.gov/2521345
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7
Control of in vivo IgE production in the mouse by interleukin 4
Autor: Fd, Finkelman, Im, Katona, Joseph Urban, We, Paul
Publikováno v: Europe PubMed Central
In vitro studies have demonstrated that the cytokine IL-4 can, with the proper co-stimuli, induce IgE secretion. We have demonstrated in in vivo studies with a monoclonal anti-IL-4 antibody that this cytokine is required for the generation of the pol
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::e6526a9907748a4107b35b1b1f288485
http://europepmc.org/abstract/med/2515949
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9
A primary intestinal helminthic infection rapidly induces a gut-associated elevation of Th2-associated cytokines and IL-3
Autor: Svetić A, Kb, Madden, Xd, Zhou, Lu P, Im, Katona, Fd, Finkelman, Joseph Urban, Wc, Gause
Publikováno v: Europe PubMed Central
The immune response that is characteristic of parasitic helminth infections includes components associated with immediate-type hypersensitivity: elevated serum IgE, eosinophilia, and intestinal mast cell hyperplasia. In infection with the parasitic n
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::e0dd21214a0ce382aabf3c735c9cda0e
http://europepmc.org/abstract/med/8468481
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10
Antibodies to IL-3 and IL-4 suppress helminth-induced intestinal mastocytosis
Autor: Kb, Madden, Joseph Urban, Hj, Ziltener, Jw, Schrader, Fd, Finkelman, Im, Katona
Publikováno v: Europe PubMed Central
Rodents infected with the nematode parasite Nippostrongylus brasiliensis (Nb) develop intestinal mastocytosis, eosinophilia, and elevated serum IgE levels. Although IL-4 and IL-5 are necessary for stimulation of IgE synthesis and eosinophilia, respec
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::cca69bfaf8bcee9fa8c69657adc3a2c3
http://europepmc.org/abstract/med/1869831
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