Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Ilya Shamovsky"'
Autor:
Ivan Gusarov, Ilya Shamovsky, Bibhusita Pani, Laurent Gautier, Svetlana Eremina, Olga Katkova-Zhukotskaya, Alexander Mironov, Alexander А. Makarov, Evgeny Nudler
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Reactive oxygen species are required for the long lifespan, and glutathione is an antioxidant. Here the authors show that limiting the consumption of dietary thiols, including those naturally derived from the microbiota, increases proteotoxic stress
Externí odkaz:
https://doaj.org/article/aa0cfd08560d47b397240eb792894996
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-8 (2019)
Hydrogen sulfide (H2S) production in Escherichia coli is controlled by the sulfurtransferase 3MST. Here, the authors describe an alternative mechanism for H2S biosynthesis via activation of the thiosulfate sulfurtransferase PspE, a process mediated b
Externí odkaz:
https://doaj.org/article/c969c6042e3e4c27ba05cd7bcae55321
Autor:
Ivan Gusarov, Ilya Shamovsky, Bibhusita Pani, Laurent Gautier, Svetlana Eremina, Olga Katkova-Zhukotskaya, Alexander Mironov, Alexander А. Makarov, Evgeny Nudler
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-1 (2021)
Externí odkaz:
https://doaj.org/article/498a510e8bd3406a90d196ffd756e0ef
Autor:
Olga Smolentseva, Ivan Gusarov, Laurent Gautier, Ilya Shamovsky, Alicia S. DeFrancesco, Richard Losick, Evgeny Nudler
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-16 (2017)
Abstract Bacteria naturally form communities of cells known as biofilms. However the physiological roles of biofilms produced by non-pathogenic microbiota remain largely unknown. To assess the impact of a biofilm on host physiology we explored the ef
Externí odkaz:
https://doaj.org/article/c600dcd1bdc7436bab0da15619883072
Autor:
Ivan Gusarov, Bibhusita Pani, Laurent Gautier, Olga Smolentseva, Svetlana Eremina, Ilya Shamovsky, Olga Katkova-Zhukotskaya, Alexander Mironov, Evgeny Nudler
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Glycogen is a storage form of glucose in cells. Here, Gusarovet al. show that glycogen-derived glucose can be used to quickly regenerate the antioxidant glutathione and that inhibiting glycogen synthesis extends C. eleganslifespan, whereas glycogen a
Externí odkaz:
https://doaj.org/article/cc5ba51eefac47af8c1cb0ac0e56b5d8
Autor:
Peter O. Fedichev, Ashok Nuthanakanti, Evgeny Nudler, Alexander Mironov, Dmitry Shishov, Ilya Shamovsky, Mirna Lechpammer, Nikita Vasilyev, Elena Shatalina, Konstantin Shatalin, Dmitri Rebatchouk, Abhishek Kaushik, Alla Peselis, Bibhusita Pani, Alexander Serganov
Publikováno v:
Science. 372:1169-1175
Turning down tolerance Persister cells, which are found in abundance in biofilms, adopt a quiescent state and survive antimicrobial treatments, seeding disease recurrence and incubating new resistance mutations. Building on work implicating the react
Autor:
Zhitai Hao, Manjunath Gowder, Sergey Proshkin, Binod K. Bharati, Vitaly Epshtein, Vladimir Svetlov, Ilya Shamovsky, Evgeny Nudler
Publikováno v:
Cell. 186:2425-2437.e21
Autor:
Samantha Vantine, Shankarling Krishnamurthy, Lingting Li, Vitaly Epshtein, Aaron Shtilerman, Evgeny Nudler, Victor J. Torres, Kayan Tam, Nikita Vasilyev, Zhitai Hao, Bibhusita Pani, Yosef Shamovsky, Carmen Vallin, Ilya Shamovsky, Aviram Rasouly, Giulio Quarta
Publikováno v:
Nat Microbiol
Mutations in the rifampicin (Rif)-binding site of RNA polymerase (RNAP) confer antibiotic resistance and often have global effects on transcription that compromise fitness and stress tolerance of resistant mutants. We suggested that the non-essential
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79977dd0b9f8dc58d129862eabd30243
https://europepmc.org/articles/PMC9389595/
https://europepmc.org/articles/PMC9389595/
Autor:
Fabian Amman, Evgeny Nudler, Ilya Shamovsky, Fatinah El-Isa, Renée Schroeder, Nadezda Sedlyarova, Andrés Magán, Natascha Hartl
Publikováno v:
Nucleic Acids Research
RNA polymerase-binding RNA aptamers (RAPs) are natural RNA elements that control transcription in cis by directly contacting RNA polymerase. Many RAPs inhibit transcription by inducing Rho-dependent termination in Escherichia coli. Here, we studied t
Autor:
Liming Hou, Ilya Shamovsky, Evgeny Nudler, Yu Liu, Nan Zhang, Brian David Dynlacht, Yating Wang, Bin Tian
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance The factors that regulate RNA polymerase II (Pol II) elongation rate and processivity are poorly understood. Here, we show that the Paf1 complex (Paf1C) modulates Pol II elongation rate, and loss of Paf1 results in accumulation of Ser5P