Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Ilya S. Steshin"'
Autor:
Dmitrii O. Shkil, Alina A. Muhamedzhanova, Philipp I. Petrov, Ekaterina V. Skorb, Timur A. Aliev, Ilya S. Steshin, Alexander V. Tumanov, Alexander S. Kislinskiy, Maxim V. Fedorov
Publikováno v:
Molecules, Vol 29, Iss 8, p 1826 (2024)
In the realm of predictive toxicology for small molecules, the applicability domain of QSAR models is often limited by the coverage of the chemical space in the training set. Consequently, classical models fail to provide reliable predictions for wid
Externí odkaz:
https://doaj.org/article/05b9b7906b4f45499baad9cfefe4cad5
Autor:
Alexander V. Vasyankin, Sergey V. Panteleev, Ilya S. Steshin, Ekaterina A. Shirokova, Alexey V. Rozhkov, Grigory D. Livshits, Eugene V. Radchenko, Stanislav K. Ignatov, Vladimir A. Palyulin
Publikováno v:
Molecules, Vol 29, Iss 3, p 696 (2024)
The emergence of new drug-resistant strains of the tuberculosis pathogen Mycobacterium tuberculosis (Mtb) is a new challenge for modern medicine. Its resistance capacity is closely related to the properties of the outer membrane of the Mtb cell wall,
Externí odkaz:
https://doaj.org/article/91022b6292434f50b760e355ed76b769
Autor:
Ilya S. Steshin, Alexander V. Vasyankin, Ekaterina A. Shirokova, Alexey V. Rozhkov, Grigory D. Livshits, Sergey V. Panteleev, Eugene V. Radchenko, Stanislav K. Ignatov, Vladimir A. Palyulin
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 2, p 1006 (2024)
The emergence of multi-drug-resistant tuberculosis strains poses a significant challenge to modern medicine. The development of new antituberculosis drugs is hindered by the low permeability of many active compounds through the extremely strong bacte
Externí odkaz:
https://doaj.org/article/296889a376d7498d89e9117929713176
Autor:
Liana A. Savintseva, Ilya S. Steshin, Alexander A. Avdoshin, Sergey V. Panteleev, Alexey V. Rozhkov, Ekaterina A. Shirokova, Grigory D. Livshits, Alexander V. Vasyankin, Eugene V. Radchenko, Stanislav K. Ignatov, Vladimir A. Palyulin
Publikováno v:
Molecules, Vol 28, Iss 3, p 1347 (2023)
Bilayers of mycolic acids (MAs) form the outer membrane of Mycobacterium tuberculosis that has high strength and extremely low permeability for external molecules (including antibiotics). For the first time, we were able to study them using the all-a
Externí odkaz:
https://doaj.org/article/78bae59306b24e6c8c8fe08ac2873286