Stable Polymer-Lipid Hybrid Nanoparticles Based on mcl-Polyhydroxyalkanoate and Cationic Liposomes for mRNA Delivery

Autor: Sergey M. Shishlyannikov, Ilya N. Zubkov, Vera V. Vysochinskaya, Nina V. Gavrilova, Olga A. Dobrovolskaya, Ekaterina A. Elpaeva, Mikhail A. Maslov, Andrey Vasin

Publikováno v: Pharmaceutics, Vol 16, Iss 10, p 1305 (2024)

Background/Objectives: The development of polymer–lipid hybrid nanoparticles (PLNs) is a promising area of research, as it can help increase the stability of cationic lipid carriers. Hybrid PLNs are core–shell nanoparticle structures that combine

Externí odkaz: https://doaj.org/article/28aba0905ea74d39a2e133bfb829ed5e

Regioselectivity of the Conjugate Addition of Amines to Dissymmetrical Pull‐Pull Alkenes

Autor: Alexander Yu. Rulev, Alexander V. Vashchenko, Ilya N. Zubkov, Igor A. Ushakov, Jacques Maddaluno, Valentin A. Semenov

Publikováno v: European Journal of Organic Chemistry
European Journal of Organic Chemistry, Wiley-VCH Verlag, 2021, 2021 (22), pp.3278-3288. ⟨10.1002/ejoc.202100325⟩

International audience; The regioselectivity of the conjugate nucleophilic addition of amines to vicinal di-acceptor-substituted alkenes has been studied. A set of results obtained with standard primary and secondary amines gives some clues on the re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0fa75eefde6cbd01856d2492e15e0e0
https://hal.archives-ouvertes.fr/hal-03440182/document