Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Ilya Lukonin"'
Publikováno v:
Experimental & Molecular Medicine
Image-based phenotypic screening relies on the extraction of multivariate information from cells cultured under a large variety of conditions. Technical advances in high-throughput microscopy enable screening in increasingly complex and biologically
Publikováno v:
Current Opinion in Cell Biology
Cells act as building blocks of multicellular organisms, forming higher-order structures at different biological scales. Niches, tissues and, ultimately, entire organisms consist of single cells that remain in constant communication. Emergence of dev
Autor:
Jeremy L. Jenkins, Katrin Volkmann, Shelly Meeusen, Prisca Liberali, Karyn Colman, Ludivine Challet Meylan, Michael B. Stadler, Ilya Lukonin, Janine E. Baaten, Denise Serra, Rui Zhao, Francisca Maurer
Publikováno v:
Nature
The development of intestinal organoids from single adult intestinal stem cells in vitro recapitulates the regenerative capacity of the intestinal epithelium1,2. Here we unravel the mechanisms that orchestrate both organoid formation and the regenera
Autor:
J Gray, Camp, Ilya, Lukonin
Publikováno v:
Nature methods. 19(3)
Autor:
Muhammad U. Anwar, Oksana A. Sergeeva, Laurence Abrami, Francisco Mesquita, Ilya Lukonin, Triana Amen, Audrey Chuat, Laura Capolupo, Prisca Liberali, Giovanni D’Angelo, F. Gisou van der Goot
Publikováno v:
SSRN Electronic Journal.
To promote infections, pathogens exploit host cell machineries including structural elements of the plasma membrane. Studying these interactions and identifying involved molecular players is an ideal way to gain insights into the fundamental biology
Autor:
J. Gray Camp, Ilya Lukonin
Publikováno v:
Nature Methods. 19:280-281
Autor:
Lauren E. Beck, Jasmine Lee, Christopher Coté, Margaret C. Dunagin, Ilya Lukonin, Nikkita Salla, Marcello K. Chang, Alex J. Hughes, Joseph D. Mornin, Zev J. Gartner, Prisca Liberali, Arjun Raj
Publikováno v:
Cell systems. 13(7)
Organoids recapitulate complex 3D organ structures and represent a unique opportunity to probe the principles of self-organization. While we can alter an organoid’s morphology by manipulating the culture conditions, the morphology of an organoid of
Autor:
Melanie Rittirsch, Michael B. Stadler, Daniel Olivieri, Panagiotis Papasaikas, Joerg Betschinger, Sébastien A. Smallwood, Ilya Lukonin, Daniel Hess
Mouse embryonic stem cells (mESCs) give rise to embryonic but not extraembryonic endoderm fates. Here, we identify the mechanism of this lineage barrier and report that the histone deacetylase Hdac3 and the corepressor Dax1 cooperatively restrict tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::171cb2c00d02a4cb4ec6b72ec7b638a1
https://doi.org/10.1101/2020.09.10.291013
https://doi.org/10.1101/2020.09.10.291013
Autor:
Austin Smith, Michael B. Stadler, Daniel Hess, Melanie Rittirsch, Maria Winzi, Joerg Betschinger, Daniela Mayer, Ilya Lukonin, Frank Buchholz
Publikováno v:
EMBO J
Developmental cell fate specification is a unidirectional process that can be reverted in response to injury or experimental reprogramming. Whether differentiation and de-differentiation trajectories intersect mechanistically is unclear. Here, we per
Autor:
Denise Serra, Urs Mayr, Andrea Boni, Ilya Lukonin, Markus Rempfler, Ludivine Challet Meylan, Michael B. Stadler, Petr Strnad, Panagiotis Papasaikas, Dario Vischi, Annick Waldt, Guglielmo Roma, Prisca Liberali
Organoids recapitulate the self-organizing capacity of stem cells and the tissue organization of the original organ in a controlled and trackable environment. Intestinal organoids, in particular, can develop from a single cell into a fully-grown stru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e876d96e1485e608b80ad87d88ebbf84
https://doi.org/10.21203/rs.2.9220/v1
https://doi.org/10.21203/rs.2.9220/v1