Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Ilya Chorny"'
Autor:
Andi Flory, Lisa McLennan, Betsy Peet, Marissa Kroll, Deirdre Stuart, Devon Brown, Kathy Stuebner, Brenda Phillips, Brenda L. Coomber, J. Paul Woods, Mairin Miller, Chelsea D. Tripp, Amber Wolf‐Ringwall, Kristina M. Kruglyak, Angela L. McCleary‐Wheeler, Ashley Phelps‐Dunn, Lilian K. Wong, Chelsea D. Warren, Gina Brandstetter, Michelle C. Rosentel, Lauren R. DiMarzio, Allison L. O'Kell, Todd A. Cohen, Daniel S. Grosu, Jason Chibuk, Dana W. Y. Tsui, Ilya Chorny, Jill M. Rafalko
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 37, Iss 1, Pp 258-267 (2023)
Abstract Background Guidelines‐driven screening protocols for early cancer detection in dogs are lacking, and cancer often is detected at advanced stages. Hypothesis/Objectives To examine how cancer typically is detected in dogs and whether the add
Externí odkaz:
https://doaj.org/article/d371ca1a414843748846f7200db24ee1
Autor:
Jill M. Rafalko, Kristina M. Kruglyak, Angela L. McCleary-Wheeler, Vidit Goyal, Ashley Phelps-Dunn, Lilian K. Wong, Chelsea D. Warren, Gina Brandstetter, Michelle C. Rosentel, Lauren DiMarzio, Lisa M. McLennan, Allison L. O’Kell, Todd A. Cohen, Daniel S. Grosu, Jason Chibuk, Dana W. Y. Tsui, Ilya Chorny, Andi Flory
Publikováno v:
PLoS ONE, Vol 18, Iss 2 (2023)
The goal of cancer screening is to detect disease at an early stage when treatment may be more effective. Cancer screening in dogs has relied upon annual physical examinations and routine laboratory tests, which are largely inadequate for detecting p
Externí odkaz:
https://doaj.org/article/850178916d354a938894d43ace134f57
Autor:
Kristina M. Kruglyak, Allison L. O’Kell, Todd A. Cohen, Maggie A. Marshall, Carlos A. Ruiz-Perez, Francesco Marass, John A. Tynan, Susan C. Hicks, Katherine M. Lytle, Ashley Phelps-Dunn, Gina Brandstetter, Chelsea D. Warren, Lauren R. DiMarzio, Michelle C. Rosentel, Lilian K. Wong, Lisa M. McLennan, Jill M. Rafalko, Daniel S. Grosu, Jason Chibuk, Ilya Chorny, Angela L. McCleary-Wheeler, Andi Flory, Dana W. Y. Tsui
Publikováno v:
Veterinary Sciences, Vol 10, Iss 7, p 455 (2023)
Age-related somatic genomic alterations in hematopoietic cell lines have been well characterized in humans; however, this phenomenon has not been well studied in other species. Next-generation sequencing-based liquid biopsy testing for cancer detecti
Externí odkaz:
https://doaj.org/article/3a9289a6ca7a4026b2f0d1f4db2b7333
Autor:
Andi Flory, Kristina M. Kruglyak, John A. Tynan, Lisa M. McLennan, Jill M. Rafalko, Patrick Christian Fiaux, Gilberto E. Hernandez, Francesco Marass, Prachi Nakashe, Carlos A. Ruiz-Perez, Donna M. Fath, Thuy Jennings, Rita Motalli-Pepio, Kate Wotrang, Angela L. McCleary-Wheeler, Susan Lana, Brenda Phillips, Brian K. Flesner, Nicole F. Leibman, Tracy LaDue, Chelsea D. Tripp, Brenda L. Coomber, J. Paul Woods, Mairin Miller, Sean W. Aiken, Amber Wolf-Ringwall, Antonella Borgatti, Kathleen Kraska, Christopher B. Thomson, Alane Kosanovich Cahalane, Rebecca L. Murray, William C. Kisseberth, Maria A. Camps-Palau, Franck Floch, Claire Beaudu-Lange, Aurélia Klajer-Peres, Olivier Keravel, Luc-André Fribourg-Blanc, Pascale Chicha Mazetier, Angelo Marco, Molly B. McLeod, Erin Portillo, Terry S. Clark, Scott Judd, C. Kirk Feinberg, Marie Benitez, Candace Runyan, Lindsey Hackett, Scott Lafey, Danielle Richardson, Sarah Vineyard, Mary Tefend Campbell, Nilesh Dharajiya, Taylor J. Jensen, Dirk van den Boom, Luis A. Diaz, Daniel S. Grosu, Arthur Polk, Kalle Marsal, Susan Cho Hicks, Katherine M. Lytle, Lauren Holtvoigt, Jason Chibuk, Ilya Chorny, Dana W. Y. Tsui
Publikováno v:
PLoS ONE, Vol 17, Iss 4 (2022)
Cancer is the leading cause of death in dogs, yet there are no established screening paradigms for early detection. Liquid biopsy methods that interrogate cancer-derived genomic alterations in cell-free DNA in blood are being adopted for multi-cancer
Externí odkaz:
https://doaj.org/article/43858f4c31a245f1a4b65cc45a0d8378
Autor:
Kristina M. Kruglyak, Jason Chibuk, Lisa McLennan, Prachi Nakashe, Gilberto E. Hernandez, Rita Motalli-Pepio, Donna M. Fath, John A. Tynan, Lauren E. Holtvoigt, Ilya Chorny, Daniel S. Grosu, Dana W.Y. Tsui, Andi Flory
Publikováno v:
Frontiers in Veterinary Science, Vol 8 (2021)
This proof-of-concept study demonstrates that blood-based liquid biopsy using next generation sequencing of cell-free DNA can non-invasively detect multiple classes of genomic alterations in dogs with cancer, including alterations that originate from
Externí odkaz:
https://doaj.org/article/bccc16909c96432baa284a9e10aaeb7b
Autor:
Jason Chibuk, Andi Flory, Kristina M. Kruglyak, Nicole Leibman, Alexis Nahama, Nilesh Dharajiya, Dirk van den Boom, Taylor J. Jensen, Jeffrey S. Friedman, M. Richard Shen, Francisco Clemente-Vicario, Ilya Chorny, John A. Tynan, Katherine M. Lytle, Lauren E. Holtvoigt, Muhammed Murtaza, Luis A. Diaz, Dana W. Y. Tsui, Daniel S. Grosu
Publikováno v:
Frontiers in Veterinary Science, Vol 8 (2021)
Cancer is the leading cause of death in dogs, in part because many cases are identified at an advanced stage when clinical signs have developed, and prognosis is poor. Increased understanding of cancer as a disease of the genome has led to the introd
Externí odkaz:
https://doaj.org/article/1a670dcb55b249c9b2b7661f3b596c77
Autor:
Allison L. O’Kell, Katherine M. Lytle, Todd A. Cohen, Lilian K. Wong, Emily Sandford, Jill M. Rafalko, Gina Brandstetter, Lauren R. DiMarzio, Ashley Phelps-Dunn, Michelle C. Rosentel, Chelsea D. Warren, Angela L. McCleary-Wheeler, Patrick C. Fiaux, Francesco Marass, Maggie A. Marshall, Carlos A. Ruiz-Perez, Kristina M. Kruglyak, John A. Tynan, Susan C. Hicks, Daniel S. Grosu, Jason Chibuk, Ilya Chorny, Dana W. Y. Tsui, Andi Flory
Publikováno v:
Journal of the American Veterinary Medical Association. :1-10
OBJECTIVE To review ordering patterns, positivity rates, and outcome data for a subset of consecutive samples submitted for a commercially available, blood-based multicancer early-detection liquid biopsy test for dogs using next-generation sequencing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::317b4ee0a610c58111789eab511a9d3f
https://doi.org/10.2460/javma.22.11.0526
https://doi.org/10.2460/javma.22.11.0526
Autor:
Tsui, Kristina M. Kruglyak, Allison L. O’Kell, Todd A. Cohen, Maggie A. Marshall, Carlos A. Ruiz-Perez, Francesco Marass, John A. Tynan, Susan C. Hicks, Katherine M. Lytle, Ashley Phelps-Dunn, Gina Brandstetter, Chelsea D. Warren, Lauren R. DiMarzio, Michelle C. Rosentel, Lilian K. Wong, Lisa M. McLennan, Jill M. Rafalko, Daniel S. Grosu, Jason Chibuk, Ilya Chorny, Angela L. McCleary-Wheeler, Andi Flory, Dana W. Y.
Publikováno v:
Veterinary Sciences; Volume 10; Issue 7; Pages: 455
Age-related somatic genomic alterations in hematopoietic cell lines have been well characterized in humans; however, this phenomenon has not been well studied in other species. Next-generation sequencing-based liquid biopsy testing for cancer detecti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::fb65415ace88ec549b83df8d2b11820e
Autor:
Daniel S. Grosu, Ilya Chorny, Kristina M. Kruglyak, John A. Tynan, Susan C. Hicks, Todd A. Cohen, Allison L. O'Kell, Jill M. Rafalko, Jason Chibuk, Angela L. McCleary-Wheeler, Andi Flory, Dana W. Tsui
Publikováno v:
Cancer Research. 83:3377-3377
Genotype-matched therapeutics have become widely adopted in the management of human cancers and can be guided by testing tumor tissue or cell-free DNA from plasma. OncoKB (Oncology Knowledge Base) is the first FDA-recognized database that contains in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3329cc0c5b601acb17cc571ca2fa5311
https://doi.org/10.1158/1538-7445.am2023-3377
https://doi.org/10.1158/1538-7445.am2023-3377
Autor:
Ilya Chorny, Angela L McCleary-Wheeler, Andi Flory, Kristina M Kruglyak, Jill M Rafalko, Daniel S Grosu, Allison L O'Kell, Todd A Cohen, Jason Chibuk, Susan C Hicks, John A Tynan, Dana WY Tsui
Publikováno v:
Blood. 140:11882-11883
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::53b3c46bdc8474de07284c3c00844447
https://doi.org/10.1182/blood-2022-169129
https://doi.org/10.1182/blood-2022-169129