Zobrazeno 1 - 10
of 246
pro vyhledávání: '"Ilya Bezprozvanny"'
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Dendritic spines form most excitatory synaptic inputs in neurons and these spines are altered in many neurodevelopmental and neurodegenerative disorders. Reliable methods to assess and quantify dendritic spines morphology are needed, but mos
Externí odkaz:
https://doaj.org/article/a80b71d069f04eb499a5bc5bdb3fa364
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/956e7fa8dadc409ca13951ee623d5627
Publikováno v:
Sensors, Vol 23, Iss 24, p 9735 (2023)
Current trends in neurobiological research focus on analyzing complex interactions within brain structures. To conduct relevant experiments, it is often essential to employ animals with unhampered mobility and utilize electrophysiological equipment c
Externí odkaz:
https://doaj.org/article/5e744420c3674528937af97cc43d848b
Autor:
Evgenii Gerasimov, Alexander Mitenev, Ekaterina Pchitskaya, Viacheslav Chukanov, Ilya Bezprozvanny
Publikováno v:
Journal of Imaging, Vol 9, Iss 11, p 243 (2023)
The visualization of neuronal activity in vivo is an urgent task in modern neuroscience. It allows neurobiologists to obtain a large amount of information about neuronal network architecture and connections between neurons. The miniscope technique mi
Externí odkaz:
https://doaj.org/article/8440de8bc1eb46d1b1907ed5afe2a08d
Publikováno v:
IBRO Neuroscience Reports, Vol 12, Iss , Pp 90-97 (2022)
Calcium/calmodulin-dependent protein kinase II (CaMKII) and neuronal store-operated calcium entry (nSOCE) have been implicated in the development of Alzheimer's disease (AD). nSOCE is involved in regulation of dendritic spine shape, particularly in s
Externí odkaz:
https://doaj.org/article/b11d841b49ae4af19b3c471be9c6d632
Autor:
Anastasiya Rakovskaya, Alexander Erofeev, Egor Vinokurov, Ekaterina Pchitskaya, Russell Dahl, Ilya Bezprozvanny
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 18, p 13973 (2023)
Alzheimer’s disease (AD) is a neurodegenerative disorder that affects memory formation and storage processes. Dysregulated neuronal calcium (Ca2+) has been identified as one of the key pathogenic events in AD, and it has been suggested that pharmac
Externí odkaz:
https://doaj.org/article/875f9eda02374e45b3661e30ba68cdff
Autor:
Meewhi Kim, Ilya Bezprozvanny
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 16, p 12980 (2023)
The sigma 1 receptor (S1R) is a 223-amino-acid-long transmembrane endoplasmic reticulum (ER) protein. The S1R plays an important role in neuronal health and it is an established therapeutic target for neurodegenerative and neuropsychiatric disorders.
Externí odkaz:
https://doaj.org/article/8ab9afc234604cc4a7855adbc15922d3
Autor:
Russell Dahl, Amanda C. Moore, Caitlynn Knight, Colleen Mauger, Hua Zhang, Gary E. Schiltz, Wendy A. Koss, Ilya Bezprozvanny
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 13, p 11057 (2023)
Alzheimer’s disease (AD) is an irreversible neurodegenerative disease that affects millions of people worldwide. AD does not have a cure and most drug development efforts in the AD field have been focused on targeting the amyloid pathway based on t
Externí odkaz:
https://doaj.org/article/fab31ecf099c4babbb8987c5c8b65d63
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 12, p 9969 (2023)
Alzheimer’s disease (AD) is one of the most widespread neurodegenerative diseases. Most of the current AD therapeutic developments are directed towards improving neuronal cell function or facilitating Aβ amyloid clearance from the brain. However,
Externí odkaz:
https://doaj.org/article/7163184daf334e35bfb42f8d76c13f56
Autor:
Hua Zhang, Ilya Bezprozvanny
Publikováno v:
Life, Vol 13, Iss 5, p 1187 (2023)
Alzheimer’s disease (AD) is the most common cause of dementia. There is a growing body of evidence that dysregulation in neuronal calcium (Ca2+) signaling plays a major role in the initiation of AD pathogenesis. In particular, it is well establishe
Externí odkaz:
https://doaj.org/article/50456470d0344644995092bebb99c40b