Zobrazeno 1 - 10
of 180
pro vyhledávání: '"Ilya A. Rybak"'
Autor:
Stephen Mari, Charly G. Lecomte, Angèle N. Merlet, Johannie Audet, Jonathan Harnie, Ilya A. Rybak, Boris I. Prilutsky, Alain Frigon
Publikováno v:
Frontiers in Systems Neuroscience, Vol 17 (2023)
IntroductionDuring locomotion, cutaneous reflexes play an essential role in rapidly responding to an external perturbation, for example, to prevent a fall when the foot contacts an obstacle. In cats and humans, cutaneous reflexes involve all four lim
Externí odkaz:
https://doaj.org/article/cd622daf61dc41efa138139d29cf4b9b
Autor:
Yongi Kim, Shinya Aoi, Soichiro Fujiki, Simon M. Danner, Sergey N. Markin, Jessica Ausborn, Ilya A. Rybak, Dai Yanagihara, Kei Senda, Kazuo Tsuchiya
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
Mammalian locomotion is generated by central pattern generators (CPGs) in the spinal cord, which produce alternating flexor and extensor activities controlling the locomotor movements of each limb. Afferent feedback signals from the limbs are integra
Externí odkaz:
https://doaj.org/article/2edbff31f39544258a077b846c691a94
Autor:
Shravan Tata Ramalingasetty, Simon M. Danner, Jonathan Arreguit, Sergey N. Markin, Dimitri Rodarie, Claudia Kathe, Gregoire Courtine, Ilya A. Rybak, Auke Jan Ijspeert
Publikováno v:
IEEE Access, Vol 9, Pp 163861-163881 (2021)
Neural control of movement cannot be fully understood without careful consideration of interactions between the neural and biomechanical components. Recent advancements in mouse molecular genetics allow for the identification and manipulation of cons
Externí odkaz:
https://doaj.org/article/08b6a9cd8bc740be8a4242efde0835d7
Autor:
Jonathan Harnie, Johannie Audet, Stephen Mari, Charly G. Lecomte, Angèle N. Merlet, Gabriel Genois, Ilya A. Rybak, Boris I. Prilutsky, Alain Frigon
Publikováno v:
Frontiers in Systems Neuroscience, Vol 16 (2022)
Locomotion after complete spinal cord injury (spinal transection) in animal models is usually evaluated in a hindlimb-only condition with the forelimbs suspended or placed on a stationary platform and compared with quadrupedal locomotion in the intac
Externí odkaz:
https://doaj.org/article/926eb7dcd732405ab4c4bc1b1b2165be
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 10, p 5541 (2022)
We describe and analyze a computational model of neural circuits in the mammalian spinal cord responsible for generating and shaping locomotor-like oscillations. The model represents interacting populations of spinal neurons, including the neurons th
Externí odkaz:
https://doaj.org/article/86b93fe5522b4f0ab338045bd8c04a48
Neural Interactions in Developing Rhythmogenic Spinal Networks: Insights From Computational Modeling
Publikováno v:
Frontiers in Neural Circuits, Vol 14 (2020)
The mechanisms involved in generation of rhythmic locomotor activity in the mammalian spinal cord remain poorly understood. These mechanisms supposedly rely on both intrinsic properties of constituting neurons and interactions between them. A subset
Externí odkaz:
https://doaj.org/article/ccb111d1645c469cab645739e9f1e09d
Autor:
Elizaveta M. Latash, Charly G. Lecomte, Simon M. Danner, Alain Frigon, Ilya A. Rybak, Yaroslav I. Molkov
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2020)
Rhythmic limb movements during locomotion are controlled by central pattern generator (CPG) circuits located in the spinal cord. It is considered that these circuits are composed of individual rhythm generators (RGs) for each limb interacting with ea
Externí odkaz:
https://doaj.org/article/37f5197d6f7547c49b28a2a2bd183db0
Autor:
Simon M. Danner, Han Zhang, Natalia A. Shevtsova, Joanna Borowska-Fielding, Dylan Deska-Gauthier, Ilya A. Rybak, Ying Zhang
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 13 (2019)
Commissural interneurons (CINs) mediate interactions between rhythm-generating locomotor circuits located on each side of the spinal cord and are necessary for left-right limb coordination during locomotion. While glutamatergic V3 CINs have been impl
Externí odkaz:
https://doaj.org/article/fd85de679d644b6d8ba65d3c8b4c94da
Publikováno v:
Frontiers in Neuroscience, Vol 13 (2019)
Central pattern generators (CPGs) in the spinal cord generate rhythmic neural activity and control locomotion in vertebrates. These CPGs operate under the control of sensory feedback that affects the generated locomotor pattern and adapt it to the an
Externí odkaz:
https://doaj.org/article/d97afcadc89c45b09f9e15629992bd17
Autor:
Taegyo Kim, Robert A. Capps, Khaldoun C. Hamade, William H. Barnett, Dmitrii I. Todorov, Elizaveta M. Latash, Sergey N. Markin, Ilya A. Rybak, Yaroslav I. Molkov
Publikováno v:
Frontiers in Neural Circuits, Vol 13 (2019)
In this study, we explore the functional role of striatal cholinergic interneurons, hereinafter referred to as tonically active neurons (TANs), via computational modeling; specifically, we investigate the mechanistic relationship between TAN activity
Externí odkaz:
https://doaj.org/article/329d0c2a68c541bfb4ffb1c3da308ea9