Zobrazeno 1 - 10
of 265
pro vyhledávání: '"Ilya, Raskin"'
Autor:
Ievgeniia Ostrov, Yongjia Gong, Joshua B Zuk, Purni C K Wickramasinghe, Irina Tmenova, Diana E Roopchand, Liping Zhao, Ilya Raskin
Publikováno v:
PLoS ONE, Vol 19, Iss 2, p e0298592 (2024)
Gut dysbiosis induced by oxygen and reactive oxygen species may be related to the development of inflammation, resulting in metabolic syndrome and associated-conditions in the gut. Here we show that elemental iron can serve as an antioxidant and reve
Externí odkaz:
https://doaj.org/article/2df1413df8784167b95b42028fbf9ddd
Autor:
Khea Wolff, Keyaara Robinson, Nanjoo Suh, Bozena Michniak-Kohn, Michael Goedken, Marianne Polunas, Ilya Raskin
Publikováno v:
Phytomedicine Plus, Vol 3, Iss 4, Pp 100479- (2023)
Background: Moringa (Moringa oleifera Lam.) seed extract (MSE) and its primary bioactive compound, moringa isothiocyanate-1(MIC-1), mitigate inflammation, oxidative stress, diabetes, and cancer in the in vivo rodent models following oral application.
Externí odkaz:
https://doaj.org/article/8d877aa15c8a4824aa5e37df1dfbb8af
Publikováno v:
Antioxidants, Vol 13, Iss 3, p 304 (2024)
Obesity and metabolic dysfunction have been shown to be associated with overproduction of reactive oxygen species (ROS) in the gastrointestinal (GI) tract, which contributes to dysbiosis or imbalances in the gut microbiota. Recently, the reversal of
Externí odkaz:
https://doaj.org/article/d42496c0ff5a45c9b1881ee2b93d4ab5
Publikováno v:
Plants, Vol 12, Iss 19, p 3467 (2023)
Flavonoids are antioxidant phytochemicals that confer a beneficial effect on human health. We have previously developed and characterized eight lettuce (Latuca sativa L.) lines that accumulated high levels of diverse flavonoids and their precursors i
Externí odkaz:
https://doaj.org/article/a260ec741aa944bf9009c784b4089122
Autor:
Badi Sri Sailaja, Sohaib Hassan, Evan Cohen, Irina Tmenova, Renalison Farias-Pereira, Michael P Verzi, Ilya Raskin
Publikováno v:
PLoS ONE, Vol 17, Iss 12, p e0279370 (2022)
This study aims to investigate the anti-inflammatory effects of moringa isothiocyanate-1 (MIC-1) extracted from seeds of Moringa oleifera Lam. in lipopolysaccharide (LPS)-induced inflammation models. MIC-1 decreased nitric oxide production and reduce
Externí odkaz:
https://doaj.org/article/113107c9e059408eb5ab5cc040630812
Autor:
Z. Elizabeth Floyd, David M. Ribnicky, Ilya Raskin, Daniel S. Hsia, Jennifer C. Rood, Bill J. Gurley
Publikováno v:
Frontiers in Nutrition, Vol 8 (2022)
A successful randomized clinical trial of the effect of dietary supplements on a chosen endpoint begins with developing supporting data in preclinical studies while paying attention to easily overlooked details when planning the related clinical tria
Externí odkaz:
https://doaj.org/article/236831d1ffce4b548e8cd53d13f5d2b8
Publikováno v:
PLoS ONE, Vol 16, Iss 4, p e0248691 (2021)
This study aims to document the dual mode of pharmacological action of moringa isothiocyanate-1 (MIC-1) derived from seeds of Moringa oleifera Lam. Oral administration of chemically stable MIC-1 (80 mg/kg) significantly reduced the expression of infl
Externí odkaz:
https://doaj.org/article/e68835a7420d42aeb2b84afb0938afd8
Autor:
Asha Jaja-Chimedza, Li Zhang, Khea Wolff, Brittany L. Graf, Peter Kuhn, Kristin Moskal, Richard Carmouche, Susan Newman, J. Michael Salbaum, Ilya Raskin
Publikováno v:
Journal of Functional Foods, Vol 47, Iss , Pp 376-385 (2018)
Moringa oleifera (moringa) has been traditionally used for the treatment of diabetes and in water purification. We previously showed that moringa seed extract (MSE), standardized to its primary bioactive isothiocyanate (MIC-1), modulated inflammatory
Externí odkaz:
https://doaj.org/article/d0d308ee44ba4cb8b9ce3d7b51c7e143
Autor:
Brittany L. Graf, Li Zhang, Maria G. Corradini, Peter Kuhn, Susan S. Newman, J. Michael Salbaum, Ilya Raskin
Publikováno v:
Journal of Functional Foods, Vol 45, Iss , Pp 268-276 (2018)
Malanga (Xanthosoma sagittifolium) is used as a medicinal food for infant development and gastritis. We compared the physicochemical properties and gut microbial effects of malanga versus potato (Solanum tuberosum) using nutritional analysis, rheomet
Externí odkaz:
https://doaj.org/article/f9f0ef4c010c452e8f08c946556322f7
Publikováno v:
Toxicology Reports, Vol 5, Iss , Pp 418-426 (2018)
A 14-d short-term oral toxicity study in rats evaluated the safety of moringa isothiocyanate-1 (MIC-1)-enriched hydro-alcoholic moringa seeds extract (MSE). Rats (5 males/5 females per group) were gavaged daily for 14 d with the vehicle control or MS
Externí odkaz:
https://doaj.org/article/c6456947e3674e3b8c69409ccf511d8f