Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Iltan, Aklan"'
Autor:
Nilufer Sayar-Atasoy, Connor Laule, Iltan Aklan, Hyojin Kim, Yavuz Yavuz, Tayfun Ates, Ilknur Coban, Fulya Koksalar-Alkan, Jacob Rysted, Debbie Davis, Uday Singh, Muhammed Ikbal Alp, Bayram Yilmaz, Huxing Cui, Deniz Atasoy
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Norepinephrine (NE) is a well-known appetite regulator, and the nor/adrenergic system is targeted by several anti-obesity drugs. To better understand the circuitry underlying adrenergic appetite control, here we investigated the paraventricu
Externí odkaz:
https://doaj.org/article/7a7b6b87fc4048c38a3160aeb85e4c0d
Autor:
Nilufer Sayar-Atasoy, Yavuz Yavuz, Connor Laule, Chunyang Dong, Hyojin Kim, Jacob Rysted, Kyle Flippo, Debbie Davis, Iltan Aklan, Bayram Yilmaz, Lin Tian, Deniz Atasoy
Publikováno v:
Cell Reports, Vol 43, Iss 1, Pp 113630- (2024)
Summary: Opioids are generally known to promote hedonic food consumption. Although much of the existing evidence is primarily based on studies of the mesolimbic pathway, endogenous opioids and their receptors are widely expressed in hypothalamic appe
Externí odkaz:
https://doaj.org/article/7b54203e42544bca939d5daa27643b6f
Autor:
Iltan Aklan, Nilufer Sayar-Atasoy, Fei Deng, Hyojin Kim, Yavuz Yavuz, Jacob Rysted, Connor Laule, Debbie Davis, Yulong Li, Deniz Atasoy
Publikováno v:
Molecular Metabolism, Vol 69, Iss , Pp 101676- (2023)
Objective: Serotonin (5HT) is a well-known anorexigenic molecule, and 5HT neurons of dorsal raphe nucleus (DRN) have been implicated in suppression of feeding; however, the downstream circuitry is poorly understood. Here we explored major projections
Externí odkaz:
https://doaj.org/article/10b3c24e4b8043df87ea5ffe937095fa
Autor:
Tayfun Ates, Merve Oncul, Pelin Dilsiz, Iskalen Cansu Topcu, Cihan Civan Civas, Muhammed Ikbal Alp, Iltan Aklan, Edanur Ates Oz, Yavuz Yavuz, Bayram Yilmaz, Nilufer Sayar Atasoy, Deniz Atasoy
Publikováno v:
Neurobiology of Disease, Vol 121, Iss , Pp 58-64 (2019)
Prader-Willi and the related Schaaf-Yang Syndromes (PWS/SYS) are rare neurodevelopmental disorders characterized by overlapping phenotypes of high incidence of autism spectrum disorders (ASD) and neonatal feeding difficulties. Based on clinical and b
Externí odkaz:
https://doaj.org/article/8417be2b48e749aaaacca7a05288ce8a
Autor:
Deniz Atasoy, Nilufer Sayar Atasoy, Yavuz Yavuz, Connor Laule, Chunyang Dong, Hyojin Kim, Iltan Aklan, Lin Tian
Publikováno v:
Physiology. 38
Opioids are generally known to promote hedonic consumption. Although much of the existing evidence is primarily based on studies in mesolimbic pathway, endogenous opioids and their receptors are widely expressed in hypothalamic appetite circuits; how
Autor:
Fulya Köksalar, İlknur Çoban, Nilufer Sayar Atasoy, Tayfun Ates, Merve Öncül, Deniz Atasoy, İltan Aklan, Gizem Filiz, Pelin Dilsiz, Yavuz Yavuz, Muhammed Ikbal Alp, Edanur Ates Oz, Utku Cebecioğlu, Bayram Yilmaz
Publikováno v:
Neuroendocrinology. 110:258-270
Background: Melanin-concentrating hormone (MCH)-expressing neurons have been implicated in regulation of energy homeostasis and reward, yet the role of their electrical activity in short-term appetite and reward modulation has not been fully understo
Autor:
Natali L, Chanaday, Elena, Nosyreva, Ok-Ho, Shin, Hua, Zhang, Iltan, Aklan, Deniz, Atasoy, Ilya, Bezprozvanny, Ege T, Kavalali
Publikováno v:
Neuron
Store operated calcium entry (SOCE) is activated by depletion of Ca(2+) from the endoplasmic reticulum (ER) and mediated by stromal interaction molecule (STIM) proteins. Here, we show that in rat and mouse hippocampal neurons acute ER Ca(2+) depletio
Autor:
Tayfun Ates, Deniz Atasoy, İltan Aklan, İlknur Çoban, Witold Konopka, Huxing Cui, Nilufer Sayar Atasoy, Merve Öncül, Fulya Köksalar, Gizem Filiz, Iskalen Cansu Topcu, Karolina Hajdukiewicz, Utku Cebecioğlu, Muhammed Ikbal Alp, Pelin Dilsiz, Deborah R. Davis, Yavuz Yavuz, Kenji Saito, Bayram Yilmaz
Publikováno v:
Cell Metab
Glucose is the essential energy source for the brain, whose deficit, triggered by energy deprivation or therapeutic agents, can be fatal. Increased appetite is the key behavioral defense against hypoglycemia; however, the central pathways involved ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da62397bddfc71ea776b6c6460ab8879
https://hdl.handle.net/20.500.12511/5121
https://hdl.handle.net/20.500.12511/5121
Autor:
Kyle H. Flippo, Samuel A.J. Trammell, Matthew P. Gillum, Iltan Aklan, Misty B. Perez, Yavuz Yavuz, Nicholas K. Smith, Sharon O. Jensen-Cody, Bolu Zhou, Kristin E. Claflin, Amy Beierschmitt, Anders Fink-Jensen, Filip K. Knop, Roberta M. Palmour, Brad A. Grueter, Deniz Atasoy, Matthew J. Potthoff
Publikováno v:
Cell Metab
Excessive alcohol consumption is a major health and social issue in our society. Pharmacologic administration of the endocrine hormone fibroblast growth factor 21 (FGF21) suppresses alcohol consumption through actions in the brain in rodents, and gen
Autor:
Ege T. Kavalali, Deniz Atasoy, Natali L. Chanaday, Hua Zhang, İltan Aklan, Ilya Bezprozvanny, Ok Ho Shin, Elena Nosyreva
Publikováno v:
Neuron. 109:1314-1332.e5
Store-operated calcium entry (SOCE) is activated by depletion of Ca2+ from the endoplasmic reticulum (ER) and mediated by stromal interaction molecule (STIM) proteins. Here, we show that in rat and mouse hippocampal neurons, acute ER Ca2+ depletion i