Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Ilse Oosterom"'
Autor:
Silva Krause, Birgit C. Schultes, Martijn Lolkema, Kristen Getchell, Lynn Zhang, Edward Cochran, Chia Lin Chu, Ilse Oosterom, Victor Farutin, Jamey Guess, Jennifer Curran, Michelle Priess, Amanda MacDonald
Supplemental Figure 1 shows Pancreatic stellate cells (PSCs) promoted tumor cell invasion through close cell-cell interactions.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a4cbed710fde6fff70072057c1d0653
https://doi.org/10.1158/1535-7163.22509292
https://doi.org/10.1158/1535-7163.22509292
Autor:
Silva Krause, Birgit C. Schultes, Martijn Lolkema, Kristen Getchell, Lynn Zhang, Edward Cochran, Chia Lin Chu, Ilse Oosterom, Victor Farutin, Jamey Guess, Jennifer Curran, Michelle Priess, Amanda MacDonald
Pancreatic cancer has an abysmal 5-year survival rate of 8%, making it a deadly disease with a need for novel therapies. Here we describe a multitargeting heparin-based mimetic, necuparanib, and its antitumor activity in both in vitro and in vivo mod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9d5af03daeb08cd8f057e5e131a81272
https://doi.org/10.1158/1535-7163.c.6539254.v1
https://doi.org/10.1158/1535-7163.c.6539254.v1
Autor:
Silva Krause, Birgit C. Schultes, Martijn Lolkema, Kristen Getchell, Lynn Zhang, Edward Cochran, Chia Lin Chu, Ilse Oosterom, Victor Farutin, Jamey Guess, Jennifer Curran, Michelle Priess, Amanda MacDonald
Supplementary Table 2 lists GO Categories significantly altered by necuparanib treatment, assigned to cancer-driving pathways
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa672d8d03409d99736c788d68c731b1
https://doi.org/10.1158/1535-7163.22509280.v1
https://doi.org/10.1158/1535-7163.22509280.v1
Autor:
Silva Krause, Birgit C. Schultes, Martijn Lolkema, Kristen Getchell, Lynn Zhang, Edward Cochran, Chia Lin Chu, Ilse Oosterom, Victor Farutin, Jamey Guess, Jennifer Curran, Michelle Priess, Amanda MacDonald
Supplementary Table 1 lists proteins significantly altered by necuparanib treatment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::469dfb91aebaa9a183ede9f1d24c2324
https://doi.org/10.1158/1535-7163.22509283.v1
https://doi.org/10.1158/1535-7163.22509283.v1
Autor:
Silva Krause, Birgit C. Schultes, Martijn Lolkema, Kristen Getchell, Lynn Zhang, Edward Cochran, Chia Lin Chu, Ilse Oosterom, Victor Farutin, Jamey Guess, Jennifer Curran, Michelle Priess, Amanda MacDonald
Supplemental Figure 3 shows MMP1 and MMP7 protein levels were unchanged in the plasma of patients.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0277567698a63467fb5213df82962200
https://doi.org/10.1158/1535-7163.22509286
https://doi.org/10.1158/1535-7163.22509286
Autor:
Silva Krause, Birgit C. Schultes, Martijn Lolkema, Kristen Getchell, Lynn Zhang, Edward Cochran, Chia Lin Chu, Ilse Oosterom, Victor Farutin, Jamey Guess, Jennifer Curran, Michelle Priess, Amanda MacDonald
Supplemental Figure 2 shows GM6001 reduced spheroid growth and invasion in the 3D co-culture model.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8304bfec79e0b08c9389f544bdfd17eb
https://doi.org/10.1158/1535-7163.22509289
https://doi.org/10.1158/1535-7163.22509289
Autor:
Chia Lin Chu, Michelle Priess, Edward Cochran, Lynn Zhang, Silva Krause, Ilse Oosterom, Birgit Schultes, Jennifer Curran, Amanda MacDonald, Kristen Getchell, Victor Farutin, Martijn P. Lolkema, Jamey Guess
Publikováno v:
Molecular Cancer Therapeutics, 18(2), 245-256. American Association for Cancer Research Inc.
Pancreatic cancer has an abysmal 5-year survival rate of 8%, making it a deadly disease with a need for novel therapies. Here we describe a multitargeting heparin-based mimetic, necuparanib, and its antitumor activity in both in vitro and in vivo mod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfc0d5b0b382853e8c466fa348201819
https://pubmed.ncbi.nlm.nih.gov/30401693
https://pubmed.ncbi.nlm.nih.gov/30401693
Publikováno v:
IntraVital, 5(3). Taylor & Francis Group
IntraVital
IntraVital
Curing pancreatic cancer is difficult as metastases often determine the poor clinical outcome. To gain more insight into the metastatic behavior of pancreatic cancer cells, we characterized migratory cells in primary pancreatic tumors using intravita
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9821c70e391f0e1c9fa2561c47e06893
https://pure.knaw.nl/portal/en/publications/864ba4ca-b393-4b2d-8064-c2dd49e964f5
https://pure.knaw.nl/portal/en/publications/864ba4ca-b393-4b2d-8064-c2dd49e964f5
Autor:
Jan Willem Gorter, Jules Becher, Ilse Oosterom, Tamis Pin, Paula Dyke, Michael Chan, Michael Shevell
Publikováno v:
Developmental Medicine & Child Neurology. 49:797-800
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::72f532d3e26479965e376dda787e5b63
https://doi.org/10.1111/j.1469-8749.2007.00797.x
https://doi.org/10.1111/j.1469-8749.2007.00797.x
Autor:
Akira Hirasawa, Marijn T M van Jaarsveld, Chris H.A. van de Lest, Steffen V F Hansen, Graeme Milligan, sahar Jafari Sadatmand, Chelsea M. McLean, Brian D. Hudson, Jeanine M.L. Roodhart, Laura G.M. Daenen, Emile E. Voest, Kenji Ishihara, Daniel S. Peeper, Julia M. Houthuijzen, Trond Ulven, Ilse Oosterom
Publikováno v:
Cancer Research. 76:307-307
Although chemotherapy is designed to eradicate tumor cells it also has a significant impact on normal tissues. These host-responses can have large effects on the efficacy of treatment and overall survival. Fatty acids are increasingly recognized to p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::050be1822c75d46e6302b321a2d00a89
https://doi.org/10.1158/1538-7445.am2016-307
https://doi.org/10.1158/1538-7445.am2016-307