Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Ilse Junghahn"'
Autor:
Klaus Brischwein, Bernd Schlereth, Rainer Kimmig, Grit Lorenczewski, Pauline Wimberger, Petra Kleindienst, Iduna Fichtner, Patrick A. Baeuerle, Ralf Lutterbuese, Ilse Junghahn, Peter Kufer, Antonio J. da Silva, Sabine Kasimir-Bauer
Publikováno v:
Cancer Research. 65:2882-2889
Bispecific T-cell engager (BiTE) are a class of bispecific single-chain antibodies that can very effectively redirect cytotoxic T cells for killing of tumor target cells. Here, we have assessed the in vivo efficacy of one representative, called bscEp
Autor:
Jutta Aumann, Andreas Nitsche, Wolfgang Siegert, Stefanie Thulke, Aleksandar Radonic, Ilse Junghahn, Iduna Fichtner
Publikováno v:
STEM CELLS. 21:236-244
In the present study we explored systematically the influence of human interleukin-3 (IL-3) on the cord blood (CB) cell-derived production of human hematopoietic cells in the bone marrow, blood, and spleen of chimeric nonobese/severe combined immunod
Publikováno v:
British Journal of Cancer
The sensitive detection of human cells in immunodeficient rodents is a prerequisite for the monitoring of micrometastasis of solid tumours, dissemination of leukaemic cells, or engraftment of haematological cells. We developed a universally applicabl
Publikováno v:
Blood. 99:719-721
At different developmental stages, candidate human hematopoietic stem cells (HSCs) are present within the CD34+ CD38− population. By means of xenotransplantation, such CD34+CD38− cells were recently shown to engraft the hematopoietic system of fe
Autor:
Gesine Bug, Reinhard Henschler, Iduna Fichtner, Stephan Göttig, Albrecht M. Müller, Ilse Junghahn, Erhard Seifried
Publikováno v:
Leukemia research. 29(10)
To better characterize acute myeloid leukemia (AML) development in non-obese diabetic (NOD)/severe combined immunodeficiency (SCID) mice, we transplanted samples from patients with AML or KG-1 and EOL-1 cell lines. We found 9/12 primary AML samples a
Autor:
Silvia-Renate Goan, U. Just, Reinhard Henschler, Manuela Wissler, Ilse Junghahn, Iduna Fichtner, Georg Martiny-Baron, Michael Becker, Jutta Aumann
Publikováno v:
Blood. 96(12)
Little is known about the presence, frequency, and in vivo proliferative potential of stromal cells within blood-derived hematopoietic transplants. In this study, nonobese diabetic/severe combined immunodeficiency (NOD/SCID) mice were injected with h
Autor:
Ilse Junghahn, Roland Mertelsmann, Dieter Möbest, Michael Becker, Iduna Fichtner, Reinhard Henschler, Silvia-Renate Goan, Julia Winkler, Elisete de Lima‐Hahn
Publikováno v:
Stem cells (Dayton, Ohio). 17(3)
So far, blood progenitor cells (BPC) expanded ex vivo in the absence of stromal cells have not been demonstrated to reconstitute hematopoiesis in myeloablated patients. To characterize the fate of early hematopoietic progenitor cells during ex vivo e
Publikováno v:
Journal of lipid mediators and cell signalling. 15(2)
Antiproliferative alkyllysophospholipid (ALP) analogs produced multiple effects on the cytosolic Ca + + concentration ([Ca + + ] i ) in an immortalized human breast epithelial cell line (H 184). The addition of small concentrations resulted in a shor
Publikováno v:
Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology. 162(4)
Protein synthesis-stimulating activity was assayed in the cytosolic fraction of white muscle from teleost fish (rainbow trout, carp) and of rat liver. In vitro protein synthesis-stimulating activity in the cytosolic fraction is reduced by food depriv