Zobrazeno 1 - 10
of 115
pro vyhledávání: '"Ilse, Rooman"'
Publikováno v:
Diagnostic Pathology, Vol 18, Iss 1, Pp 1-6 (2023)
Abstract Heterotopia of the salivary gland occurs mainly in the head and neck region of the human body, rarely in regions such as the rectum, but has never been demonstrated in the pancreas. Within a screening effort of pancreatic samples for detecti
Externí odkaz:
https://doaj.org/article/7dabf8fa7cce44a78ed6b1a32d3ccd07
Autor:
Zhaolong Pan, Jan-Lars Van den Bossche, Eva Rodriguez-Aznar, Pauline Janssen, Olaya Lara, Gamze Ates, Ann Massie, Diedert Luc De Paep, Isabelle Houbracken, Marco Mambretti, Ilse Rooman
Publikováno v:
Cell Death and Disease, Vol 14, Iss 8, Pp 1-10 (2023)
Abstract Acinar cell dedifferentiation is one of the most notable features of acute and chronic pancreatitis. It can also be the initial step that facilitates pancreatic cancer development. In the present study, we further decipher the precise mechan
Externí odkaz:
https://doaj.org/article/adf246e9954541b490c2843a354e56e2
Autor:
Elyne Backx, Katarina Coolens, Jan-Lars Van den Bossche, Isabelle Houbracken, Elisa Espinet, Ilse Rooman
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 13, Iss 4, Pp 1243-1253 (2022)
Pancreatic ductal adenocarcinoma (PDAC) is a devastating type of cancer. While many studies have shed light into the pathobiology of PDAC, the nature of PDAC’s cell of origin remains under debate. Studies in adult pancreatic tissue have unveiled a
Externí odkaz:
https://doaj.org/article/672711a25da84b37a2c43cad208150d5
Autor:
Lindsay Sprimont, Pauline Janssen, Kathleen De Swert, Mathias Van Bulck, Ilse Rooman, Jacques Gilloteaux, Ann Massie, Charles Nicaise
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract xCT is the specific subunit of System xc-, an antiporter importing cystine while releasing glutamate. Although xCT expression has been found in the spinal cord, its expression and role after spinal cord injury (SCI) remain unknown. The aim o
Externí odkaz:
https://doaj.org/article/0c960f346c93467d92befefbdd905a9b
Publikováno v:
Trials, Vol 22, Iss 1, Pp 1-13 (2021)
Abstract Background Finding new therapeutic uses for existing medicines could lead to safe, affordable and timely new treatment options for patients with high medical needs. However, due to a lack of economic incentives, pharmaceutical developers are
Externí odkaz:
https://doaj.org/article/8b4146836b254f7a8e2fb37fdada10df
Autor:
Andreia V. Pinho, Mathias Van Bulck, Lorraine Chantrill, Mehreen Arshi, Tatyana Sklyarova, David Herrmann, Claire Vennin, David Gallego-Ortega, Amanda Mawson, Marc Giry-Laterriere, Astrid Magenau, Gunther Leuckx, Luc Baeyens, Anthony J. Gill, Phoebe Phillips, Paul Timpson, Andrew V. Biankin, Jianmin Wu, Ilse Rooman
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
SLIT-ROBO alterations arise in pancreatic ductal adenocarcinoma (PDAC), but their role in the pancreas is unclear. Here, the authors use mouse models to show that loss of epithelial Robo2 activates the neighbouring stroma via TGF-β signalling; findi
Externí odkaz:
https://doaj.org/article/7bcf752c0ac345e8b916a29cc45a9a4f
Autor:
Sarah K. Hakuno, Ellis Michiels, Eleonore B. Kuhlemaijer, Ilse Rooman, Lukas J. A. C. Hawinkels, Marije Slingerland
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 6, p 3147 (2022)
Cancers affecting the gastrointestinal system are highly prevalent and their incidence is still increasing. Among them, gastric and pancreatic cancers have a dismal prognosis (survival of 5–20%) and are defined as difficult-to-treat cancers. This r
Externí odkaz:
https://doaj.org/article/62b83fdde03e42758cdd9bfd4e5b25aa
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2020)
Repurposing of medicines has gained a lot of interest from the research community in recent years as it could offer safe, timely, and affordable new treatment options for cancer patients with high unmet needs. Increasingly, questions arise on how new
Externí odkaz:
https://doaj.org/article/cf06adf726ad475eb7927d94875bad8e
Autor:
Andreas Trumpp, Martin R. Sprick, Wilko Weichert, Oliver Strobel, Janel L. Kopp, Ilse Rooman, H. Efsun Arda, Dieter Weichenhan, Katja Steiger, Benedikt Brors, Christoph Plass, Thilo Hackert, Nicole Pfarr, Matthias Schlesner, Roland Eils, Hsi-Yu Yen, Elisa Donato, Manuel Rodríguez-Paredes, Matthias M. Gaida, Soheila Zarei, Elyne Backx, Alex Y.L. Lee, Karnjit Sarai, Alexander Muckenhuber, Steffi O. Kossi, Vera Thiel, Manuel Reitberger, Jacob Insua-Rodríguez, Mattia Falcone, Vanessa Vogel, Corinna Klein, Silke Weisenburger, Mariam Safavi, Magdalena Büscher, Nathalia A. Giese, Charles D. Imbusch, Zuguang Gu, Elisa Espinet
Supplementary Figures S1 to S15
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c6bcfdd799ab0ad68bc5c33c677dcd0
https://doi.org/10.1158/2159-8290.22536175.v1
https://doi.org/10.1158/2159-8290.22536175.v1
Autor:
Andreas Trumpp, Martin R. Sprick, Wilko Weichert, Oliver Strobel, Janel L. Kopp, Ilse Rooman, H. Efsun Arda, Dieter Weichenhan, Katja Steiger, Benedikt Brors, Christoph Plass, Thilo Hackert, Nicole Pfarr, Matthias Schlesner, Roland Eils, Hsi-Yu Yen, Elisa Donato, Manuel Rodríguez-Paredes, Matthias M. Gaida, Soheila Zarei, Elyne Backx, Alex Y.L. Lee, Karnjit Sarai, Alexander Muckenhuber, Steffi O. Kossi, Vera Thiel, Manuel Reitberger, Jacob Insua-Rodríguez, Mattia Falcone, Vanessa Vogel, Corinna Klein, Silke Weisenburger, Mariam Safavi, Magdalena Büscher, Nathalia A. Giese, Charles D. Imbusch, Zuguang Gu, Elisa Espinet
MC1vsMC2 DE genes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::929e7117e7b8cdebf430057e700f582a
https://doi.org/10.1158/2159-8290.22536157.v1
https://doi.org/10.1158/2159-8290.22536157.v1