Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Ilona Zemlyak"'
Autor:
Nathan C Manley, Javier R Caso, Melissa G Works, Andrew B Cutler, Ilona Zemlyak, Guohua Sun, Carolina D Munhoz, Sydney Chang, Shawn F Sorrells, Florian V Ermini, Johannes H Decker, Anthony A Bertrand, Klaus M Dinkel, Gary K Steinberg, Robert M Sapolsky
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e61789 (2013)
Research with experimental stroke models has identified a wide range of therapeutic proteins that can prevent the brain damage caused by this form of acute neurological injury. Despite this, we do not yet have safe and effective ways to deliver thera
Externí odkaz:
https://doaj.org/article/154739d33a4d47efbb8c8dbc7ba44152
Publikováno v:
Neuroscience Letters. 469:179-183
Neuronal apoptosis following ischemia can be mediated by a caspase-dependent pathway, which involves the mitochondrial release of cytochrome c that initiates a cascade of caspase activation. In addition, there is a caspase-independent pathway, which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bd60365a7c3b35d4650e010480729d2
https://doi.org/10.1016/j.neulet.2009.11.067
https://doi.org/10.1016/j.neulet.2009.11.067
Publikováno v:
Neuroscience Letters. 453:182-185
Apoptosis arises from neuronal damage following an ischemic insult. Apoptosis-inducing factor (AIF) is a protein released from mitochondria in response to pro-apoptotic signals which then translocates to the nucleus and triggers DNA fragmentation. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63c673f40d78b46457a8d4dfb4ad21b7
https://doi.org/10.1016/j.neulet.2009.02.020
https://doi.org/10.1016/j.neulet.2009.02.020
Publikováno v:
Regulatory Peptides. 96:39-43
We have recently cloned a novel protein (activity-dependent neuroprotective protein, ADNP) containing an 8-amino-acid, femtomolar-acting peptide, NAPVSIPQ (NAP). Here we show, for the first time, that NAP exerted a protective effect on glia-depleted
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11a3dc4124efdbd753a4ca47eb8813a5
https://doi.org/10.1016/s0167-0115(00)00198-1
https://doi.org/10.1016/s0167-0115(00)00198-1
Autor:
Marat Gorivodsky, Ilona Zemlyak, Hasida Orenstein, Shoshana Savion, Amos Fein, Arkady Torchinsky, Vladimir Toder
Publikováno v:
The Journal of Immunology. 160:4280-4288
An elevated expression of TNF-α in embryonic microenvironment was found to be associated with postimplantation loss. In this work, we examined the pattern of TNF-α expression at both the mRNA and the protein level as well as the distribution of TNF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0802cb28d29f06bc7e20da653afe571b
https://doi.org/10.4049/jimmunol.160.9.4280
https://doi.org/10.4049/jimmunol.160.9.4280
Autor:
Carolina Demarchi Munhoz, Shawn F. Sorrells, Anthony A. Bertrand, Javier R. Caso, Andrew Cutler, Sydney Chang, Gary K. Steinberg, Melissa Works, Florian V. Ermini, Guohua Sun, Klaus Dinkel, Johannes H. Decker, Robert M. Sapolsky, Ilona Zemlyak, Nathan C. Manley
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
PLoS ONE, Vol 8, Iss 4, p e61789 (2013)
PLoS ONE
Universidade de São Paulo (USP)
instacron:USP
PLoS ONE, Vol 8, Iss 4, p e61789 (2013)
PLoS ONE
Research with experimental stroke models has identified a wide range of therapeutic proteins that can prevent the brain damage caused by this form of acute neurological injury. Despite this, we do not yet have safe and effective ways to deliver thera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e0190b842bb2374d561d86910946bb5
Publikováno v:
Journal of neural transmission (Vienna, Austria : 1996). 116(11)
The peptide NAP (NAPVSIPQ) was shown to protect neurons against a wide variety of insults. Particularly, NAP was shown to be neuroprotective in vitro against cyanide in hippocampal cultures and against oxygen-glucose deprivation in hippocampal and co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14258eef766f16057c79800efc32d595
https://pubmed.ncbi.nlm.nih.gov/19551468
https://pubmed.ncbi.nlm.nih.gov/19551468
Publikováno v:
European journal of pharmacology. 618(1-3)
NAPVSIPQ (NAP), an 8 amino acid peptide derived from activity-dependent neuroprotective protein (ADNP), provides neuroprotection through interaction with microtubules. Previous results have demonstrated NAP protection against oxygen-glucose deprivati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35671cee4c4b31bc816d7406d0f96e82
https://pubmed.ncbi.nlm.nih.gov/19619522
https://pubmed.ncbi.nlm.nih.gov/19619522
Publikováno v:
Peptides. 28(10)
The femtomolar-acting protective peptide NAP (NAPVSIPQ), derived from activity-dependent neuroprotective protein (ADNP), is broadly neuroprotective in vivo and in vitro in cerebral cortical cultures and a variety of cell lines. In the present study,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca86295abf48b309f09a5dc0ed92e8e1
https://pubmed.ncbi.nlm.nih.gov/17869381
https://pubmed.ncbi.nlm.nih.gov/17869381
Autor:
Vitaliy Nimon, Robert M. Sapolsky, Ilona Zemlyak, Tejaswini Moore, John McLaughlin, Sheila M. Brooke
Publikováno v:
Brain research. 1088(1)
Neuronal death following necrotic insults involves the generation of reactive oxygen species (ROS). We investigated the effects of antioxidant gene therapy on ROS accumulation after exposure to either sodium cyanide, kainic acid or oxygen glucose dep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1189118f555bbddd23f2477bafa9b8ad
https://pubmed.ncbi.nlm.nih.gov/16630587
https://pubmed.ncbi.nlm.nih.gov/16630587