Výsledky vyhledávání - "Ilona Schonn"

Cellular responses to etoposide: cell death despite cell cycle arrest and repair of DNA damage

Autor: Jana Hennesen, Ilona Schonn, Dorothee C. Dartsch

Publikováno v: Apoptosis. 15:162-172

The topoisomerase IIalpha inhibitor etoposide is a 'broad spectrum' anticancer agent and a potent inducer of DNA double strand breaks. DNA damage response of mammalian cells usually involves cell cycle arrest and DNA repair or, if unsuccessful, cell

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55dd4579f6436fb64ac8a73ef1b6de5c
https://doi.org/10.1007/s10495-009-0440-9

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Ku70 and Rad51 vary in their importance for the repair of doxorubicin- versus etoposide-induced DNA damage

Autor: Jana Hennesen, Ilona Schonn, Dorothee C. Dartsch

Publikováno v: Apoptosis : an international journal on programmed cell death. 16(4)

For DNA targeting anticancer drugs, cellular DNA repair mechanisms may cause resistance and hamper the therapeutic outcome. DNA damage induced by topoisomerase IIα inhibitors like etoposide and anthracyclines, which are a mainstay of cancer therapy,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d47b40d63df223905f6495548c87fe7b
https://pubmed.ncbi.nlm.nih.gov/21107697

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