Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Ilona Mandrika"'
Autor:
Maiju K. Rinne, Lauri Urvas, Ilona Mandrika, Dāvids Fridmanis, Darren M. Riddy, Christopher J. Langmead, Jyrki P. Kukkonen, Henri Xhaard
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Tunicates are evolutionary model organisms bridging the gap between vertebrates and invertebrates. A genomic sequence in Ciona intestinalis (CiOX) shows high similarity to vertebrate orexin receptors and protostome allatotropin receptors (AT
Externí odkaz:
https://doaj.org/article/3532f53292dc43e187ca5d3298309620
Autor:
Greta Gedvilaite-Vaicechauskiene, Loresa Kriauciuniene, Arimantas Tamasauskas, Vita Rovite, Ilona Mandrika, Sheng-Nan Wu, Chin-Wei Huang, Lina Poskiene, Rasa Liutkeviciene
Publikováno v:
Medicina, Vol 60, Iss 8, p 1252 (2024)
Background and Objectives: This study explores the complex pathogenesis of pituitary adenomas (PAs), prevalent intracranial tumors in the pituitary gland. Despite their generally benign nature, PAs exhibit a diverse clinical spectrum involving hormon
Externí odkaz:
https://doaj.org/article/94cac27050e744549fdb60a5a7012498
Autor:
Rihards Saksis, Olesja Rogoza, Helvijs Niedra, Kaspars Megnis, Ilona Mandrika, Inga Balcere, Liva Steina, Janis Stukens, Austra Breiksa, Jurijs Nazarovs, Jelizaveta Sokolovska, Ilze Konrade, Raitis Peculis, Vita Rovite
Publikováno v:
Cancer Cell International, Vol 23, Iss 1, Pp 1-21 (2023)
Abstract Pituitary neuroendocrine tumours (PitNETs) are neoplasms of the pituitary that overproduce hormones or cause unspecific symptoms due to mass effect. Growth hormone overproducing GH-producing PitNETs cause acromegaly leading to connective tis
Externí odkaz:
https://doaj.org/article/29d030e8136840839256602be7185efa
Autor:
Helvijs Niedra, Raitis Peculis, Helena Daiga Litvina, Kaspars Megnis, Ilona Mandrika, Inga Balcere, Mihails Romanovs, Liva Steina, Janis Stukens, Austra Breiksa, Jurijs Nazarovs, Jelizaveta Sokolovska, Rasa Liutkeviciene, Alvita Vilkevicute, Ilze Konrade, Vita Rovite
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
BackgroundCirculating plasma miRNAs have been increasingly studied in the field of pituitary neuroendocrine tumor (PitNET) research. Our aim was to discover circulating plasma miRNAs species associated with growth hormone (GH) secreting PitNETs versu
Externí odkaz:
https://doaj.org/article/d0a09e78ef7a42a8bbe8b9ca8021d4a0
Autor:
Rihards Saksis, Ivars Silamikelis, Pola Laksa, Kaspars Megnis, Raitis Peculis, Ilona Mandrika, Olesja Rogoza, Ramona Petrovska, Inga Balcere, Ilze Konrade, Liva Steina, Janis Stukens, Austra Breiksa, Jurijs Nazarovs, Jelizaveta Sokolovska, Valdis Pirags, Janis Klovins, Vita Rovite
Publikováno v:
Frontiers in Oncology, Vol 10 (2021)
Acromegaly is a disease mainly caused by pituitary neuroendocrine tumor (PitNET) overproducing growth hormone. First-line medication for this condition is the use of somatostatin analogs (SSAs), that decrease tumor mass and induce antiproliferative e
Externí odkaz:
https://doaj.org/article/21c8d3f4b1734708aa6b19d24003d7b9
Autor:
Raitis Peculis, Ilona Mandrika, Ramona Petrovska, Rasma Dortane, Kaspars Megnis, Jurijs Nazarovs, Inga Balcere, Janis Stukens, Ilze Konrade, Valdis Pirags, Janis Klovins, Vita Rovite
Publikováno v:
Frontiers in Endocrinology, Vol 11 (2020)
The most common type of pituitary neoplasms is benign pituitary adenoma (PA). Clinically significant PAs affect around 0.1% of the population. Currently, there is no established human PA cell culture available and when PA tumor cells are cultured the
Externí odkaz:
https://doaj.org/article/24adec672d884f5bace37d1afd35bc3f
Autor:
Egils Bisenieks, Brigita Vigante, Ramona Petrovska, Baiba Turovska, Ruslan Muhamadejev, Vitalijs Soloduns, Astrida Velena, Karlis Pajuste, Luciano Saso, Janis Klovins, Gunars Duburs, Ilona Mandrika
Publikováno v:
Pharmaceuticals, Vol 14, Iss 10, p 987 (2021)
The paradigm of ligand-receptor interactions postulated as “one compound—one target” has been evolving; a multi-target, pleiotropic approach is now considered to be realistic. Novel series of 1,4,5,6,7,8-hexahydro-5-oxoquinolines, pyranopyrimid
Externí odkaz:
https://doaj.org/article/8caf4940419f481f9c13e6506e351cd8
Autor:
Anatoly Mishnev, Egils Bisenieks, Ilona Mandrika, Ramona Petrovska, Zenta Kalme, Imanta Bruvere, Gunars Duburs
Publikováno v:
Acta Crystallographica Section E: Crystallographic Communications, Vol 74, Iss 11, Pp 1577-1579 (2018)
In the title compound, C25H25NO5S, which exhibits metabolism-regulating activity, the 1,4-dihydropyridine ring adopts a flattened boat conformation while the cyclohexenone ring is in an envelope conformation. Molecules in the crystal are assembled in
Externí odkaz:
https://doaj.org/article/3935d33eb2f34602b859ed3ce3165738
Autor:
Kaspars Megnis, Ilona Mandrika, Ramona Petrovska, Janis Stukens, Vita Rovite, Inga Balcere, Laima Sabine Jansone, Raitis Peculis, Valdis Pirags, Janis Klovins
Publikováno v:
Stem Cells International, Vol 2016 (2016)
Pituitary adenomas are one of the most common endocrine and intracranial neoplasms. Although they are theoretically monoclonal in origin, several studies have shown that they contain different multipotent cell types that are thought to play an import
Externí odkaz:
https://doaj.org/article/b5885d393dc64ce0ba5f10e38e77773c
Autor:
Baiba Zandersone, Iveta Liduma, Ramona Petrovska, Tatjana Tracevska, Sujith Eranezhath, Arnolds Jezupovs, Ilona Mandrika, Somit Kumar, Valdis Pirags
Publikováno v:
Evidence-Based Complementary and Alternative Medicine, Vol 2021 (2021)
Evidence-based Complementary and Alternative Medicine : eCAM
Evidence-based Complementary and Alternative Medicine : eCAM
Objective. Polyherbal formulations Jathyadi Thailam and Jatyadi Ghritam (JT) are used in Indian traditional medicine for diabetic chronic wounds, fistula, fissure, eczema, and burn management. We aimed to investigate the antibacterial and anti-inflam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ec2b7d3452e340b960c8dc14a61bbe9