Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Ilona Kariv"'
Autor:
Christopher J. Dinsmore, Nancy E. Kohl, Qinwen Zeng, Alexander A. Szewczak, John F. Reilly, Xianlu Qu, Cloud P. Paweletz, Bart A. Lutterbach, Wei Lu, Kaiko Kunii, Jason D. Katz, Ilona Kariv, James P. Jewell, Harold Hatch, Gaozhen Hang, Susana Gil, Jackson B. Gibbs, Sujal V. Deshmukh, Lenora J. Davis, An Chi, Melissa Chenard, Grace K.Y. Chan, Bo-Sheng Pan
Supplementary Figure 3 from MK-2461, a Novel Multitargeted Kinase Inhibitor, Preferentially Inhibits the Activated c-Met Receptor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37ead8a2c84ec1e9b5c7fd484d5aa73e
https://doi.org/10.1158/0008-5472.22383779
https://doi.org/10.1158/0008-5472.22383779
Autor:
Christopher J. Dinsmore, Nancy E. Kohl, Qinwen Zeng, Alexander A. Szewczak, John F. Reilly, Xianlu Qu, Cloud P. Paweletz, Bart A. Lutterbach, Wei Lu, Kaiko Kunii, Jason D. Katz, Ilona Kariv, James P. Jewell, Harold Hatch, Gaozhen Hang, Susana Gil, Jackson B. Gibbs, Sujal V. Deshmukh, Lenora J. Davis, An Chi, Melissa Chenard, Grace K.Y. Chan, Bo-Sheng Pan
Supplementary Figure 4 from MK-2461, a Novel Multitargeted Kinase Inhibitor, Preferentially Inhibits the Activated c-Met Receptor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::054140e8884713105eec245eadc1cdda
https://doi.org/10.1158/0008-5472.22383776
https://doi.org/10.1158/0008-5472.22383776
Autor:
Christopher J. Dinsmore, Nancy E. Kohl, Qinwen Zeng, Alexander A. Szewczak, John F. Reilly, Xianlu Qu, Cloud P. Paweletz, Bart A. Lutterbach, Wei Lu, Kaiko Kunii, Jason D. Katz, Ilona Kariv, James P. Jewell, Harold Hatch, Gaozhen Hang, Susana Gil, Jackson B. Gibbs, Sujal V. Deshmukh, Lenora J. Davis, An Chi, Melissa Chenard, Grace K.Y. Chan, Bo-Sheng Pan
Supplementary Figure 2 from MK-2461, a Novel Multitargeted Kinase Inhibitor, Preferentially Inhibits the Activated c-Met Receptor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a65a09f92681267a6de3aaaa88df405
https://doi.org/10.1158/0008-5472.22383782
https://doi.org/10.1158/0008-5472.22383782
Autor:
Christopher J. Dinsmore, Nancy E. Kohl, Qinwen Zeng, Alexander A. Szewczak, John F. Reilly, Xianlu Qu, Cloud P. Paweletz, Bart A. Lutterbach, Wei Lu, Kaiko Kunii, Jason D. Katz, Ilona Kariv, James P. Jewell, Harold Hatch, Gaozhen Hang, Susana Gil, Jackson B. Gibbs, Sujal V. Deshmukh, Lenora J. Davis, An Chi, Melissa Chenard, Grace K.Y. Chan, Bo-Sheng Pan
Supplementary Figure 1 from MK-2461, a Novel Multitargeted Kinase Inhibitor, Preferentially Inhibits the Activated c-Met Receptor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72d584751769fb485b613b5d4da0b8ad
https://doi.org/10.1158/0008-5472.22383785
https://doi.org/10.1158/0008-5472.22383785
Autor:
Christopher J. Dinsmore, Nancy E. Kohl, Qinwen Zeng, Alexander A. Szewczak, John F. Reilly, Xianlu Qu, Cloud P. Paweletz, Bart A. Lutterbach, Wei Lu, Kaiko Kunii, Jason D. Katz, Ilona Kariv, James P. Jewell, Harold Hatch, Gaozhen Hang, Susana Gil, Jackson B. Gibbs, Sujal V. Deshmukh, Lenora J. Davis, An Chi, Melissa Chenard, Grace K.Y. Chan, Bo-Sheng Pan
Supplementary Figure 5 from MK-2461, a Novel Multitargeted Kinase Inhibitor, Preferentially Inhibits the Activated c-Met Receptor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::698732c4b28be2c0e774afa90e7f46c3
https://doi.org/10.1158/0008-5472.22383773.v1
https://doi.org/10.1158/0008-5472.22383773.v1
Autor:
Christopher J. Dinsmore, Nancy E. Kohl, Qinwen Zeng, Alexander A. Szewczak, John F. Reilly, Xianlu Qu, Cloud P. Paweletz, Bart A. Lutterbach, Wei Lu, Kaiko Kunii, Jason D. Katz, Ilona Kariv, James P. Jewell, Harold Hatch, Gaozhen Hang, Susana Gil, Jackson B. Gibbs, Sujal V. Deshmukh, Lenora J. Davis, An Chi, Melissa Chenard, Grace K.Y. Chan, Bo-Sheng Pan
Supplementary Methods, Table 1, Figure Legends 1-5 from MK-2461, a Novel Multitargeted Kinase Inhibitor, Preferentially Inhibits the Activated c-Met Receptor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a4bf79ff1fd442ca0667d231c5117b6
https://doi.org/10.1158/0008-5472.22383770.v1
https://doi.org/10.1158/0008-5472.22383770.v1
Autor:
Wonsuk Chang, Michael D. Altman, Charles A. Lesburg, Samanthi A. Perera, Jennifer A. Piesvaux, Gottfried K. Schroeder, Daniel F. Wyss, Saso Cemerski, Yiping Chen, Edward DiNunzio, Andrew M. Haidle, Thu Ho, Ilona Kariv, Ian Knemeyer, Johnny E. Kopinja, Brian M. Lacey, Jason Laskey, Jongwon Lim, Brian J. Long, Yanhong Ma, Matthew L. Maddess, Bo-Sheng Pan, Jeremy P. Presland, Edward Spooner, Dietrich Steinhuebel, Quang Truong, Zhibo Zhang, Jianmin Fu, George H. Addona, Alan B. Northrup, Emma Parmee, James R. Tata, David Jonathan Bennett, Jared N. Cumming, Tony Siu, B. Wesley Trotter
Publikováno v:
Journal of medicinal chemistry. 65(7)
Stereochemically and structurally complex cyclic dinucleotide-based stimulator of interferon genes (STING) agonists were designed and synthesized to access a previously unexplored chemical space. The assessment of biochemical affinity and cellular po
Autor:
Laura Price, Samanthi A. Perera, Daniel F. Wyss, Johnny E. Kopinja, Saso Cemerski, Sharad K. Sharma, Timothy J. Henderson, Serena Xu, Andrew M. Haidle, Min Lu, George H. Addona, Greg O’Donnell, Berengere Sauvagnat, Gottfried K. Schroeder, Ilona Kariv, Larissa Rakhilina, Sriram Tyagarajan, Bo-Sheng Pan, Hyun Chong Woo, Brian Long, Jared N. Cumming, Brandon Cash, Yiping Chen, Ryan D. Otte, B. Wesley Trotter, Jeremy Presland, Jennifer Piesvaux, Brian M. Lacey, Rui Liang, Peter J. Dandliker, Ellen C. Minnihan, Charles A. Lesburg, Ian Knemeyer, Yanhong Ma, Guo Feng, David Jonathan Bennett, Michael D. Altman, Alexei V. Buevich, Jason Laskey, James P. Jewell, Wonsuk Chang
Publikováno v:
Signal Transduction and Targeted Therapy
Pharmacological activation of the STING (stimulator of interferon genes)-controlled innate immune pathway is a promising therapeutic strategy for cancer. Here we report the identification of MSA-2, an orally available non-nucleotide human STING agoni
Autor:
Jeffrey T. Borenstein, Daniel Doty, Troy Lau, John R. Chevillet, Alla A. Gimbel, Lily Y. Moy, Nathan Moore, N. Lowry, Vienna L. Mott, Hongmin Chen, Jose A. Santos, G. Addona, Ilona Kariv, Mark Zielstorff, Louis B. Kratchman
Publikováno v:
Lab on a Chip. 18:1844-1858
Recapitulation of the tumor microenvironment is critical for probing mechanisms involved in cancer, and for evaluating the tumor-killing potential of chemotherapeutic agents, targeted therapies and immunotherapies. Microfluidic devices have emerged a
Autor:
George H. Addona, Eric S. Muise, Benjamin Nicholson, Rachel Altura, Michelle R. Machacek, Jennifer Cho, Hongmin Chen, Haiyan Xu, Lan Chen, Ilona Kariv, My Sam Mansueto, Razvan Cristescu, Nicole Follmer, Kimberley Kerr, Sarah Javaid
Publikováno v:
Journal of Cellular and Molecular Medicine
This study reports the establishment of a bone marrow mononuclear cell (BMMC) 3D culture model and the application of this model to define sensitivity and resistance biomarkers of acute myeloid leukaemia (AML) patient bone marrow samples in response