Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Ilona Hagelstein"'
Autor:
Ilona Hagelstein, Laura Wessling, Alexander Rochwarger, Latifa Zekri, Boris Klimovich, Christian M. Tegeler, Gundram Jung, Christian M. Schürch, Helmut R. Salih, Martina S. Lutz
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-15 (2024)
Abstract Background Breast cancer (BC) is the most common malignancy in women. Immunotherapy has revolutionized treatment options in many malignancies, and the introduction of immune checkpoint inhibition yielded beneficial results also in BC. Howeve
Externí odkaz:
https://doaj.org/article/4fe2b27d65564a37932f57ac8d6d6e06
Autor:
Sylwia A. Stefańczyk, Ilona Hagelstein, Martina S. Lutz, Stefanie Müller, Samuel J. Holzmayer, Grace Jarjour, Latifa Zekri, Jonas S. Heitmann, Helmut R. Salih, Melanie Märklin
Publikováno v:
Blood Cancer Journal, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Acute myeloid leukemia (AML) remains a therapeutic challenge despite recent therapeutic advances. Although monoclonal antibodies (mAbs) engaging natural killer (NK) cells via antibody-dependent cellular cytotoxicity (ADCC) hold promise in ca
Externí odkaz:
https://doaj.org/article/d7bb9722631649bdb4aa52e985e69282
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Sarcomas are rare and heterogeneous malignancies that are difficult to treat. Approximately 50% of patients diagnosed with sarcoma develop metastatic disease with so far very limited treatment options. The transmembrane protein B7-H3 reportedly is ex
Externí odkaz:
https://doaj.org/article/e3b1784090fa44b59e048df06e322d59
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Pancreatic cancer is a highly lethal disease with limited treatment options. Hence, there is a considerable medical need for novel treatment strategies. Monoclonal antibodies (mAbs) have significantly improved cancer therapy, primarily due to their a
Externí odkaz:
https://doaj.org/article/53bad62c2c5e41ed83ea58e6d30172d5
Autor:
Anna Seller, Christian M. Tegeler, Jonas Mauermann, Tatjana Schreiber, Ilona Hagelstein, Kai Liebel, André Koch, Jonas S. Heitmann, Sarah M. Greiner, Clara Hayn, Dominik Dannehl, Tobias Engler, Andreas D. Hartkopf, Markus Hahn, Sara Y. Brucker, Helmut R. Salih, Melanie Märklin
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 7, p 4126 (2024)
Ligands of the natural killer group 2D (NKG2DL) family are expressed on malignant cells and are usually absent from healthy tissues. Recognition of NKG2DLs such as MICA/B and ULBP1-3 by the activating immunoreceptor NKG2D, expressed by NK and cytotox
Externí odkaz:
https://doaj.org/article/021392ba532f41ac8a84f90b20ae0442
Autor:
Ilona Hagelstein, Gundram Jung, Helmut R Salih, Latifa Zekri, Martina S Lutz, Laura Weßling, Christian M Tegeler
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/bf5eb3c2eb8e4c64ad07901d9dce6651
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/d26ab3dfa98d4425aa769bd58051a293
Autor:
Melanie Märklin, Ilona Hagelstein, Jonas S Heitmann, Helmut R Salih, Latifa Zekri, Martina S Lutz, Sylwia A Stefanczyk, Stefanie Müller
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/93c5d23431ca45e9942f42b7396aba0c
Autor:
Ilona Hagelstein, Kathrin Rothfelder, Jonas S Heitmann, Helmut R Salih, Sylwia A Stefanczyk, Kim L Clar, Jonas Rieth
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/224cba73dfd54cf383f3151122ec7639
Autor:
Ilona Hagelstein, Monika Engel, Clemens Hinterleitner, Timo Manz, Melanie Märklin, Gundram Jung, Helmut R. Salih, Latifa Zekri
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Natural killer (NK) cells largely contribute to antibody-dependent cellular cytotoxicity (ADCC), a central factor for success of monoclonal antibodies (mAbs) treatment of cancer. The B7 family member B7-H3 (CD276) recently receives intense interest a
Externí odkaz:
https://doaj.org/article/6f74fb34d359468886f07e79d2af2908