Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Ilona Domracheva"'
Autor:
Reinis Putralis, Ksenija Korotkaja, Martins Kaukulis, Zhanna Rudevica, Juris Jansons, Olga Nilova, Martins Rucins, Laura Krasnova, Ilona Domracheva, Mara Plotniece, Karlis Pajuste, Arkadij Sobolev, Felikss Rumnieks, Laura Bekere, Anna Zajakina, Aiva Plotniece, Gunars Duburs
Publikováno v:
Pharmaceuticals, Vol 16, Iss 9, p 1245 (2023)
A set of styrylpyridinium (SP) compounds was synthesised in order to study their spectroscopic and cell labelling properties. The compounds comprised different electron donating parts (julolidine, p-dimethylaminophenyl, p-methoxyphenyl, 3,4,5-trimeth
Externí odkaz:
https://doaj.org/article/c72d1fe3c07644e092e19883f53d7ef5
Autor:
Marina Makrecka-Kuka, Pavels Dimitrijevs, Ilona Domracheva, Kristaps Jaudzems, Maija Dambrova, Pavel Arsenyan
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Abstract The development of targeted drugs for the treatment of cancer remains an unmet medical need. This study was designed to investigate the mechanism underlying breast cancer cell growth suppression caused by fused isoselenazolium salts. The abi
Externí odkaz:
https://doaj.org/article/9530a9b4b9d8471ea4c2facbb29d7c84
Autor:
Klavs Pajuste, Martins Rucins, Ilona Domracheva, Arkadij Sobolev, Nadiia Pikun, Mara Plotniece, Gunars Duburs, Karlis Pajuste, Aiva Plotniece
Publikováno v:
Data in Brief, Vol 33, Iss , Pp 106545- (2020)
In this data file the synthetic procedures for preparation of the original 4-pyridinium-1,4-dihydropyridines (4-Py-1,4-DHP) and their parent compounds – dialkyl 2,6-dimethyl-4-(3-pyridyl)-1,4-dihydropyridine-3,5-dicarboxylates were described. In to
Externí odkaz:
https://doaj.org/article/9223f1ff398c4a9fa9d5e86a17f8d9da
Autor:
Ilona Domracheva, Ruslan Muhamadejev, Marina Petrova, Edvards Liepinsh, Anita Gulbe, Irina Shestakova, Gunars Duburs, Pavel Arsenyan
Publikováno v:
Toxicology Reports, Vol 2, Iss C, Pp 377-383 (2015)
Addition of DMPC considerably inhibits the degradation of Carmofur in neutral phosphate buffer solutions and this drug becomes less influenced by pH. Carmofur stabilization at neutral pH caused by DMPC addition for in vitro studies was characterized
Externí odkaz:
https://doaj.org/article/2efb2ea3afd140c9b3a1669e338b32b8
Autor:
Martins Rucins, Pavels Dimitrijevs, Klavs Pajuste, Oksana Petrichenko, Ludmila Jackevica, Anita Gulbe, Signe Kibilda, Krisjanis Smits, Mara Plotniece, Dace Tirzite, Karlis Pajuste, Arkadij Sobolev, Janis Liepins, Ilona Domracheva, Aiva Plotniece
Publikováno v:
Pharmaceutics, Vol 11, Iss 3, p 115 (2019)
The design of nanoparticle delivery materials possessing biological activities is an attractive strategy for the development of various therapies. In this study, 11 cationic amphiphilic 4-(N-alkylpyridinium)-1,4-dihydropyridine (1,4-DHP) derivatives
Externí odkaz:
https://doaj.org/article/e6bb0efd137046cc8539b508b29ed21d
Autor:
Jelena Vasiljeva, Marina Makrecka-Kuka, Ilona Domracheva, Karlis Vilks, Pavels Dimitrijevs, Pavel Arsenyan
Publikováno v:
New Journal of Chemistry. 46:7424-7432
Selenophenoquinolinone is a prospective scaffold for the development of ABCB1 inhibitors for the treatment of MDR cancers.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::63b215adced75fc9443f5308f6771218
https://doi.org/10.1039/d2nj00340f
https://doi.org/10.1039/d2nj00340f
Publikováno v:
Chemistry of Heterocyclic Compounds. 57:848-856
Synthetic procedures for the preparation of selenophenochromones by treating ethynyl chromones with selenium halides were elaborated. Methyl 3-bromo-2-(1-hydroxycyclohexyl)-9-oxo-9 H -selenopheno[2,3- f ]chromene-7-carboxylate exhibits high selective
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9ea0a97a17385c1864dcfd37f4d653a1
https://doi.org/10.1007/s10593-021-02990-8
https://doi.org/10.1007/s10593-021-02990-8
Publikováno v:
Chemistry of Heterocyclic Compounds. 56:776-785
Synthetic procedures for the preparation of 8-ethynylxanthines by treating 8-bromocaffeine and 8-bromopentoxifylline with terminal acetylenes were elaborated. Certain ethynylxanthine derivatives exhibit high in vitro antiproliferative activity agains
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f1256b11aa2093a0eafac8591c5872a
https://doi.org/10.1007/s10593-020-02730-4
https://doi.org/10.1007/s10593-020-02730-4
Autor:
Arkadij Sobolev, Natalya P. Kolesnyk, Ilona Domracheva, Yuriy G. Shermolovich, Aiva Plotniece, Eduard B. Rusanov, Nadiia V. Pikun
Publikováno v:
New Journal of Chemistry. 43:10537-10544
The reactivity and synthetic utility of dialkyl 2,4-diacetyl-2,4-difluoro-3-phenylpentanedioates 1 (2,6-heptanediones) as new fluorinated reagents prepared from the reaction of 1,4-dihydropyridines with Selectfluor® for the synthesis of carbocycles
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::30d55e7cc8915e68bf165d7941770c62
https://doi.org/10.1039/c9nj01446b
https://doi.org/10.1039/c9nj01446b
Publikováno v:
New Journal of Chemistry. 43:11851-11864
The general aim of the current research is to find novel non-toxic small molecules with antimetastatic activity. Herein we present a series of novel selenopheno[2,3-f]coumarins with low cytotoxicity profiles against cancer cells with different nature
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c755bea79872ddb335aba7bd9cc61c95
https://doi.org/10.1039/c9nj01682a
https://doi.org/10.1039/c9nj01682a