Výsledky vyhledávání - "Ilona Aylott"

Abstract 4097: Functional and translatable efficacy of CAR-T cells targeting B cell lymphomas

Autor: Lauren Kelsey, Karin Latta, Joey Kolb, Bincy John, Ilona Aylott, Daniel Rocca, Alexandru Bacita, Christopher Kirkham, Patrick Walters, Charlotte Humphery, Lorena Sueiro Ballesteros, Jezrom Self-Fordham, Louise Brackenbury, Chassidy Hall, Harris David, Julia Schueler, Robert Nunan

Publikováno v: Cancer Research. 83:4097-4097

Chimeric Antigen Receptor (CAR)-T cell therapy has achieved great success in treating a variety of liquid tumors, in particular CD19+ lymphomas. CAR technology is advancing rapidly, with notable improvements in efficacy, safety and complexity as huma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::51a89f5fb6184aade91288ca0c18f921
https://doi.org/10.1158/1538-7445.am2023-4097

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Abstract 2843: Development of a translatable CD19 CAR-T platform for drug discovery

Autor: Lauren Kelsey, Jezrom Self-Fordham, Eva Oswald, Ilona Aylott, Daniel Rocca, Robert Nunan, David Harris, Julia Schueler, Rhiannon Jenkinson

Publikováno v: Cancer Research. 82:2843-2843

Chimeric Antigen Receptor (CAR)-T cell therapy has achieved great success with specificity, efficacy, safety and ingenuity. CAR cell technology is advancing rapidly, with ever increasing capabilities for cancer treatment both with regard to tumor typ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4125ea81f29e47f837986285b6bc1b92
https://doi.org/10.1158/1538-7445.am2022-2843

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Abstract 2229: A panel of NSCLC patient derived xenografts displays a distinct sensitivity profile towards checkpoint inhibitor treatment in vitro and in vivo

Autor: Friedrich Feuerhake, Eva Oswald, Robert Nunan, Julia Schüler, Rhiannon Jenkinson, Ilona Aylott

Publikováno v: Cancer Research. 80:2229-2229

The field of cancer immunology is rapidly moving towards innovative therapeutic strategies. As a consequence there is a need for robust and predictive preclinical platforms for assessing therapies. The current project aims to establish a drug screeni

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::26c975cc38e840e2c7c8ce38963e5859
https://doi.org/10.1158/1538-7445.am2020-2229

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Abstract 3865: A translational immuno-oncology platform to model T cell activation and Tex recovery in the tumor microenvironment

Autor: Louise Harvey, Rhiannon Jenkinson, Ilona Aylott, Michelle Yap, Robert Nunan, Hannah Gill, Tommaso Iannitti

Publikováno v: Cancer Research. 80:3865-3865

The tumor microenvironment (TME) is a complex network, consisting of malignant tumor cells, stromal and immune cells, blood vessels, extracellular matrix and soluble factors. The immune system plays an important role in combating tumor growth, and mu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f7cb8549ec4924a0aafe852d8aa38f95
https://doi.org/10.1158/1538-7445.am2020-3865

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