Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Ilona, Ormsby"'
Publikováno v:
The Scientific World Journal, Vol 1, Pp 146-146 (2001)
Externí odkaz:
https://doaj.org/article/fe4995247478485c9a52f57f097027fb
Autor:
George F. Babcock, Thomas Doetschman, Ramireddy Bommireddy, Ilona Ormsby, Jennifer H. Martin, Jeffery D. Molkentin, Gregory P. Boivin, C. Gard, H. Chen, Orlando F. Bueno
Publikováno v:
Clinical and Experimental Immunology. 158:317-324
Transforming growth factor (TGF) beta1) is an immunoregulatory cytokine involved in self-tolerance and lymphocyte homeostasis. Tgfb1 knock-out (KO) mice develop severe multi-focal autoimmune inflammatory lesions due to [Ca(2+)]i deregulation in T cel
Autor:
Mariya Hristova, Marion Bohatschek, Andrea Koppius, Thomas Doetschman, Ilona Ormsby, Karl Bauer, Milan Makwana, Dietmute Bueringer, Gennadij Raivich, Heike Heuer, Leonard L. Jones, Dan Cuthill, Sönke Friedrichsen
Publikováno v:
The Journal of Neuroscience. 27:11201-11213
Transforming growth factor beta1 (TGFbeta1) is a pleiotropic cytokine with potent neurotrophic and immunosuppressive properties that is upregulated after injury, but also expressed in the normal nervous system. In the current study, we examined the r
Autor:
Gregory P. Boivin, Moying Yin, Ilona Ormsby, Ramireddy Bommireddy, Thomas Doetschman, George F. Babcock
Publikováno v:
The Journal of Immunology. 170:3645-3652
TGFβ1 is a polypeptide growth modulatory and differentiation factor involved in many biological processes including immune homeostasis and self-tolerance. Tgfb1 knockout mice die around weaning age due to severe inflammation in most major organ syst
Publikováno v:
Journal of Biological Chemistry. 274:31008-31013
Upon activation, platelets store and release large amounts of the peptide transforming growth factor beta1 (TGFbeta1). The released TGFbeta1 can then act on nearby vascular cells to mediate subsequent vessel repair. In addition, TGFbeta1 may circulat
Publikováno v:
Molecular Reproduction and Development. 52:341-349
There is incomplete penetrance to Tgfb1 knockout phenotypes. About 50% of Tgfb1 homozygous mutant (Tgfb1−/−) and 25% of Tgfb1 heterozygous (Tgfb1+/−) embryos die during embryogenesis. In a mixed NIH/Ola × C57BL/6J/Ola × 129 background partial
Publikováno v:
The Journal of Immunology. 161:154-160
Previous studies have suggested that oral tolerance induction by low doses of Ag is mediated by inhibitory cytokines, particularly TGF-β1. To examine the roles of TGF-β1 and other inhibitory cytokines in the induction of oral tolerance, TGF-β1 nul
Publikováno v:
Wound Repair and Regeneration. 3:25-36
To investigate the role of transforming growth factor-beta(1) in tissue repair, we performed wound healing studies in the transforming growth factor-beta(1)-deficient mouse with targeted disruption of the transforming growth factor-beta(1) gene. Tran
Autor:
Ilona Ormsby, Gabriele Proetzel, Ronald J. Diebold, Moying Yin, Marcia M. Shull, Dawn Calvin, Charles L. Sidman, Thomas Doetschman, Ruth D. Allen, Nikki Annunziata, Ann B. Kier, Sharon A. Pawlowski
Publikováno v:
Nature. 359:693-699
Transforming growth factor-beta 1 (TGF-beta 1) is a multifunctional growth factor that has profound regulatory effects on many developmental and physiological processes. Disruption of the TGF-beta 1 gene by homologous recombination in murine embryoni
Autor:
Gregory P. Boivin, Jeffery D. Molkentin, Jennifer H. Martin, Orlando F. Bueno, Ilona Ormsby, Dora Chen, Thomas Doetschman, Ramireddy Bommireddy, George F. Babcock
Publikováno v:
The FASEB Journal. 22