Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Ilnour Ourmanov"'
Autor:
Fan Wu, Andrea Kirmaier, Robert Goeken, Ilnour Ourmanov, Laura Hall, Jennifer S Morgan, Kenta Matsuda, Alicia Buckler-White, Keiko Tomioka, Ronald Plishka, Sonya Whitted, Welkin Johnson, Vanessa M Hirsch
Publikováno v:
PLoS Pathogens, Vol 9, Iss 8, p e1003577 (2013)
The antagonistic interaction with host restriction proteins is a major driver of evolutionary change for viruses. We previously reported that polymorphisms of the TRIM5α B30.2/SPRY domain impacted the level of SIVsmm viremia in rhesus macaques. Vire
Externí odkaz:
https://doaj.org/article/4e07c97e33b24134a67bed1a15b59390
Autor:
Takeo Kuwata, Yoshiaki Nishimura, Sonya Whitted, Ilnour Ourmanov, Charles R Brown, Que Dang, Alicia Buckler-White, Ranjini Iyengar, Jason M Brenchley, Vanessa M Hirsch
Publikováno v:
PLoS Pathogens, Vol 5, Iss 4, p e1000372 (2009)
The progressive decline of CD4(+) T cells is a hallmark of disease progression in human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV) infection. Whereas the acute phase of the infection is dominated by virus-mediated depletion
Externí odkaz:
https://doaj.org/article/d1962e6ff9e24476927633e2aaa8c877
Autor:
Fan Wu, Jinghe Huang, David C. Montefiori, Andrea Kirmaier, Vanessa M. Hirsch, Kenta Matsuda, Celia C. LaBranche, Sonya Whitted, Sivan Leviyang, Ilnour Ourmanov
Publikováno v:
J Clin Invest
The development of broadly neutralizing antibodies (BNAbs) in HIV infection is a result of long-term coevolutionary interaction between viruses and antibodies. Understanding how this interaction promotes the increase of neutralization breadth during
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01e1563fb502d70255662f013cbb92fe
https://europepmc.org/articles/PMC7524488/
https://europepmc.org/articles/PMC7524488/
Autor:
Ronald J. Plishka, Ellen White, Andrea Kirmaier, Jennifer S. Morgan, Vanessa M. Hirsch, Nadeene E. Riddick, Sonya Whitted, Welkin E. Johnson, Fan Wu, Kenta Matsuda, Ilnour Ourmanov, Alicia Buckler-White, Laura R. Hall
Publikováno v:
Journal of Virology. 90:11087-11095
TRIM5α polymorphism limits and complicates the use of simian immunodeficiency virus (SIV) for evaluation of human immunodeficiency virus (HIV) vaccine strategies in rhesus macaques. We previously reported that the TRIM5α-sensitive SIV from sooty ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17894514163528d58f062392b22a02cc
https://doi.org/10.1128/jvi.01620-16
https://doi.org/10.1128/jvi.01620-16
Autor:
Shuzo Matsushita, Fan Wu, Ikumi Enomoto, Takeo Kuwata, Vanessa M. Hirsch, Kaori Takaki, Kazuhisa Yoshimura, Hironori Sato, Ilnour Ourmanov, Masaru Yokoyama
Publikováno v:
Journal of Virology. 87:5424-5436
Inducing neutralizing antibodies (NAb) is the key to developing a protective vaccine against human immunodeficiency virus type 1 (HIV-1). To clarify the neutralization mechanism of simian immunodeficiency virus (SIV), we analyzed NAb B404, which show
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f547bac71d998ba61378d1e7595c41f
https://doi.org/10.1128/jvi.00201-13
https://doi.org/10.1128/jvi.00201-13
Autor:
Simoy Goldstein, Nadeene E. Riddick, Fan Wu, Kenta Matsuda, Jason M. Brenchley, Ronald J. Plishka, Alicia Buckler-White, Robert M. Goeken, Ilnour Ourmanov, Sonya Whitted, Vanessa M. Hirsch
African green monkeys (AGM) are natural hosts of simian immunodeficiency virus (SIV), and infection in these animals is generally nonpathogenic, whereas infection of nonnatural hosts, such as rhesus macaques (RM), is commonly pathogenic. CCR5 has bee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c15285745b679b33e09b6437e6b657d6
https://europepmc.org/articles/PMC4810715/
https://europepmc.org/articles/PMC4810715/
Autor:
Robert M. Goeken, Ilnour Ourmanov, Alicia Buckler-White, Vanessa M. Hirsch, Charles R. Brown, Ronald J. Plishka, Fan Wu, Scott T. Aoki, Takeo Kuwata, Ranjini Iyengar
Publikováno v:
Journal of Virology. 86:8835-8847
Simian immunodeficiency virus (SIV) infection of rhesus macaques has become an important surrogate model for evaluating HIV vaccine strategies. The extreme resistance to neutralizing antibody (NAb) of many commonly used strains, such as SIVmac251/239
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac8d852880781d74bc9a8e6b59db2b7a
https://doi.org/10.1128/jvi.00923-12
https://doi.org/10.1128/jvi.00923-12
Autor:
Takeo Kuwata, Robert M. Goeken, Alicia Buckler-White, Ilnour Ourmanov, Bernard A. P. Lafont, Vanessa M. Hirsch, Simoy Goldstein, Ranjani Iyengar
Publikováno v:
Journal of Virology. 83:5388-5400
Previous studies demonstrated that immunization of macaques with simian immunodeficiency virus (SIV) Gag-Pol and Env recombinants of the attenuated poxvirus modified vaccinia virus Ankara (MVA) provided protection from high viremia and AIDS following
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c8123697ff4efb12184d62f77669d791
https://doi.org/10.1128/jvi.02598-08
https://doi.org/10.1128/jvi.02598-08
Publikováno v:
Virology. 372:291-299
A nonintegrating mutant, SIVsmD116N, was derived from the infectious pathogenic SIVsmE543-3 clone by introducing an Asp (D) to Asn (N) mutation into the catalytic domain of integrase. Although SIVsmD116N generated all viral proteins following transfe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00eac40bd2add71a5638d2c725f334b5
https://doi.org/10.1016/j.virol.2007.11.002
https://doi.org/10.1016/j.virol.2007.11.002
Autor:
Vanessa M. Hirsch, Que Dang, Meggan Czapiga, Yoshiaki Nishimura, Ilnour Ourmanov, Malcolm A. Martin, Charles R. Brown, Juraj Kabat
Publikováno v:
Journal of Virology. 81:5594-5606
Human immunodeficiency virus type 1 (HIV-1), the causative agent of AIDS in humans, results in a progressive depletion of CD4+ T lymphocytes that culminates in fatal immunodeficiency. Although it is clear that HIV is responsible for massive early des
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8210baaee4a82b1e3757589f8c24ad73
https://doi.org/10.1128/jvi.00202-07
https://doi.org/10.1128/jvi.00202-07