Zobrazeno 1 - 10
of 219
pro vyhledávání: '"Ilmo Leivo"'
Autor:
Linda Nissi, Sanni Tuominen, Johannes Routila, Teemu Huusko, Petra Ketonen, Maria Sundvall, Ilmo Leivo, Heikki Irjala, Heikki Minn, Tove J. Grönroos, Sami Ventelä
Publikováno v:
Cancer Medicine, Vol 13, Iss 21, Pp n/a-n/a (2024)
ABSTRACT Background xCT, also known as SLC7A11 (solute carrier Family 7 Member 11), is a cystine/glutamate antiporter protein that mediates regulated cell death and antioxidant defense. The aim of this study was to investigate the effect of xCT on th
Externí odkaz:
https://doaj.org/article/eb07ca8478a24ba99fc48fb427fd5f96
Autor:
Lauri J. Sipilä, Riku Katainen, Mervi Aavikko, Janne Ravantti, Iikki Donner, Rainer Lehtonen, Ilmo Leivo, Henrik Wolff, Reetta Holmila, Kirsti Husgafvel-Pursiainen, Lauri A. Aaltonen
Publikováno v:
Genes and Environment, Vol 46, Iss 1, Pp 1-13 (2024)
Abstract Background Sinonasal adenocarcinoma is a rare cancer, encompassing two different entities, the intestinal-type sinonasal adenocarcinoma (ITAC) and the non-intestinal-type sinonasal adenocarcinoma (non-ITAC). Occurrence of ITAC is strongly as
Externí odkaz:
https://doaj.org/article/13bdffe712f4463f8322241bddd8c7e2
Autor:
Alhadi Almangush, Jaana Hagström, Caj Haglund, Luiz Paulo Kowalski, Ricardo D. Coletta, Antti A. Mäkitie, Tuula Salo, Ilmo Leivo
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-8 (2024)
Abstract Background The clinical significance of single cell invasion and large nuclear diameter is not well documented in early-stage oral tongue squamous cell carcinoma (OTSCC). Methods We used hematoxylin and eosin-stained sections to evaluate the
Externí odkaz:
https://doaj.org/article/adbd8a253cd7461e81f222f65d991e7b
Autor:
Noora Lehtinen, Janne Suhonen, Kiesha Rice, Eetu Välimäki, Mervi Toriseva, Johannes Routila, Perttu Halme, Melissa Rahi, Heikki Irjala, Ilmo Leivo, Markku Kallajoki, Matthias Nees, Teijo Kuopio, Sami Ventelä, Juha K. Rantala
Publikováno v:
Translational Oncology, Vol 44, Iss , Pp 101935- (2024)
Malignant tumors derived from the epithelium lining the nasal cavity region are termed sinonasal cancers, a highly heterogeneous group of rare tumors accounting for 3 – 5 % of all head and neck cancers. Progress with next-generation molecular profi
Externí odkaz:
https://doaj.org/article/1043b19b0c8148dc8cfad7e1e4daf8d5
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Nasopharyngeal cancer (NPC) has a unique histopathology compared with other head and neck cancers. Individual NPC patients may attain different outcomes. This study aims to build a prognostic system by combining a highly accurate machine lea
Externí odkaz:
https://doaj.org/article/2305d183b1d54139b5c76a3c3fd30c80
Autor:
Sanni Tuominen, Linda Nissi, Antti Kukkula, Johannes Routila, Teemu Huusko, Ilmo Leivo, Heikki Minn, Heikki Irjala, Eliisa Löyttyniemi, Sami Ventelä, Maria Sundvall, Tove J. Grönroos
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
BackgroundTreatment resistance and relapse are common problems in head and neck squamous cell carcinoma (HNSCC). Except for p16, no clinically accepted prognostic biomarkers are available for HNSCC. New biomarkers predictive of recurrence and surviva
Externí odkaz:
https://doaj.org/article/e593201e187a47768d76a1ee1ab78441
Autor:
Alhadi Almangush, Ibrahim O. Bello, Amr Elseragy, Jaana Hagström, Caj Haglund, Luiz Paulo Kowalski, Pentti Nieminen, Ricardo D. Coletta, Antti A. Mäkitie, Tuula Salo, Ilmo Leivo
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-6 (2022)
Abstract Background The clinical significance of tertiary lymphoid structures (TLSs) is not well-documented in early oral tongue squamous cell carcinoma (OTSCC). Methods A total of 310 cases of early (cT1-2N0) OTSCC were included in this multicenter
Externí odkaz:
https://doaj.org/article/17aed296411f4823bc0cec4a880723dc
Autor:
Eva-Maria Talvitie, Lassi Liljeroos, Heikki Vilhonen, Katri Orte, Ilmo Leivo, Markku Kallajoki, Pekka Taimen
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 32, Iss , Pp 100832- (2022)
Introduction: Lung adenocarcinoma is the most common type of lung cancer and typically carries a high number of mutations. However, the genetic background of the tumors varies according to patients’ ethnic background and smoking status. Little data
Externí odkaz:
https://doaj.org/article/2e128498bc3b480c89b8d9cb6100759a
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-11 (2021)
Abstract Background Currently, no clinically useful biomarkers for radioresistance are available in head and neck squamous cell carcinoma (HNSCC). This study assesses the usefulness of Cell Line Microarray (CMA) method to enhance immunohistochemical
Externí odkaz:
https://doaj.org/article/f0828836158445368d358d37a6fa25f5
Autor:
Alhadi Almangush, Rasheed Omobolaji Alabi, Giuseppe Troiano, Ricardo D. Coletta, Tuula Salo, Matti Pirinen, Antti A. Mäkitie, Ilmo Leivo
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-8 (2021)
Abstract Background The clinical significance of tumor-stroma ratio (TSR) has been examined in many tumors. Here we systematically reviewed all studies that evaluated TSR in head and neck cancer. Methods Four databases (Scopus, Medline, PubMed and We
Externí odkaz:
https://doaj.org/article/a3cbdc50972d497babcf591d7997abb6