SARS-CoV-2 infection predisposes patients to coinfection with Staphylococcus aureus .

Autor: Lubkin A; Department of Microbiology, New York University Grossman School of Medicine, New York, New York, USA., Bernard-Raichon L; Department of Microbiology, New York University Grossman School of Medicine, New York, New York, USA.; Division of Gastroenterology and Hepatology, Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA., DuMont AL; Department of Microbiology, New York University Grossman School of Medicine, New York, New York, USA., Valero Jimenez AM; Department of Microbiology, New York University Grossman School of Medicine, New York, New York, USA., Putzel GG; Department of Microbiology, New York University Grossman School of Medicine, New York, New York, USA.; Antimicrobial-Resistant Pathogens Program, Microbial Genomics Core Lab, New York University Langone Health, New York, New York, USA., Gago J; Department of Population Health, New York University Grossman School of Medicine, New York, New York, USA., Zwack EE; Department of Microbiology, New York University Grossman School of Medicine, New York, New York, USA., Olusanya O; Department of Microbiology, New York University Grossman School of Medicine, New York, New York, USA.; Antimicrobial-Resistant Pathogens Program, Microbial Genomics Core Lab, New York University Langone Health, New York, New York, USA., Boguslawski KM; Department of Microbiology, New York University Grossman School of Medicine, New York, New York, USA., Dallari S; Department of Microbiology, New York University Grossman School of Medicine, New York, New York, USA., Dyzenhaus S; Department of Microbiology, New York University Grossman School of Medicine, New York, New York, USA., Herrmann C; Department of Microbiology, New York University Grossman School of Medicine, New York, New York, USA., Ilmain JK; Department of Microbiology, New York University Grossman School of Medicine, New York, New York, USA., Isom GL; Department of Microbiology, New York University Grossman School of Medicine, New York, New York, USA., Pawline M; Department of Microbiology, New York University Grossman School of Medicine, New York, New York, USA.; Department of Medicine, NYU Grossman School of Medicine, New York, New York, USA., Perault AI; Department of Microbiology, New York University Grossman School of Medicine, New York, New York, USA.; Antimicrobial-Resistant Pathogens Program, Microbial Genomics Core Lab, New York University Langone Health, New York, New York, USA., Perelman S; Department of Microbiology, New York University Grossman School of Medicine, New York, New York, USA., Sause WE; Department of Microbiology, New York University Grossman School of Medicine, New York, New York, USA., Shahi I; Department of Microbiology, New York University Grossman School of Medicine, New York, New York, USA., St John A; Department of Microbiology, New York University Grossman School of Medicine, New York, New York, USA., Tierce R; Division of Comparative Medicine, New York University Langone Health, New York, New York, USA., Zheng X; Department of Microbiology, New York University Grossman School of Medicine, New York, New York, USA., Zhou C; Department of Microbiology, New York University Grossman School of Medicine, New York, New York, USA.; Department of Medicine, NYU Grossman School of Medicine, New York, New York, USA., Noval MG; Department of Microbiology, New York University Grossman School of Medicine, New York, New York, USA., O'Keeffe A; Department of Microbiology, New York University Grossman School of Medicine, New York, New York, USA., Podkowik M; Department of Microbiology, New York University Grossman School of Medicine, New York, New York, USA.; Antimicrobial-Resistant Pathogens Program, Microbial Genomics Core Lab, New York University Langone Health, New York, New York, USA., Gonzales S; Department of Microbiology, New York University Grossman School of Medicine, New York, New York, USA., Inglima K; Department of Medicine, NYU Grossman School of Medicine, New York, New York, USA., Desvignes L; Department of Medicine, NYU Grossman School of Medicine, New York, New York, USA.; High Containment Laboratories, Office of Science and Research, NYU Langone Health, New York, New York, USA., Hochman SE; Antimicrobial-Resistant Pathogens Program, Microbial Genomics Core Lab, New York University Langone Health, New York, New York, USA.; Department of Medicine, NYU Grossman School of Medicine, New York, New York, USA., Stapleford KA; Department of Microbiology, New York University Grossman School of Medicine, New York, New York, USA., Thorpe LE; Department of Population Health, New York University Grossman School of Medicine, New York, New York, USA., Pironti A; Department of Microbiology, New York University Grossman School of Medicine, New York, New York, USA.; Antimicrobial-Resistant Pathogens Program, Microbial Genomics Core Lab, New York University Langone Health, New York, New York, USA., Shopsin B; Department of Microbiology, New York University Grossman School of Medicine, New York, New York, USA.; Antimicrobial-Resistant Pathogens Program, Microbial Genomics Core Lab, New York University Langone Health, New York, New York, USA.; Department of Medicine, NYU Grossman School of Medicine, New York, New York, USA., Cadwell K; Division of Gastroenterology and Hepatology, Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA., Dittmann M; Department of Microbiology, New York University Grossman School of Medicine, New York, New York, USA., Torres VJ; Department of Microbiology, New York University Grossman School of Medicine, New York, New York, USA.; Antimicrobial-Resistant Pathogens Program, Microbial Genomics Core Lab, New York University Langone Health, New York, New York, USA.

Publikováno v: MBio [mBio] 2024 Aug 14; Vol. 15 (8), pp. e0166724. Date of Electronic Publication: 2024 Jul 22.

Unlatching of the stem domains in the Staphylococcus aureus pore-forming leukocidin LukAB influences toxin oligomerization.

Autor: Ilmain JK; Department of Microbiology, New York University Grossman School of Medicine, New York, New York, USA., Perelman SS; Department of Microbiology, New York University Grossman School of Medicine, New York, New York, USA., Panepinto MC; Proteomics Laboratory, Division of Advanced Research Technologies, New York University Grossman School of Medicine, New York, New York, USA., Irnov I; Department of Microbiology, New York University Grossman School of Medicine, New York, New York, USA., Coudray N; Applied Bioinformatics Laboratories, New York University Grossman School of Medicine, New York, New York, USA; Department of Cell Biology, New York University Grossman School of Medicine, New York, New York, USA., Samhadaneh N; Antimicrobial-Resistant Pathogens Program, New York University Langone Health, New York, New York, USA., Pironti A; Department of Microbiology, New York University Grossman School of Medicine, New York, New York, USA; Antimicrobial-Resistant Pathogens Program, New York University Langone Health, New York, New York, USA., Ueberheide B; Proteomics Laboratory, Division of Advanced Research Technologies, New York University Grossman School of Medicine, New York, New York, USA; Department of Biochemistry and Molecular Pharmacology, New York University Grossman School of Medicine, New York, New York, USA; Department of Neurology, Center for Cognitive Neurology, New York University Grossman School of Medicine, New York, New York, USA., Ekiert DC; Department of Microbiology, New York University Grossman School of Medicine, New York, New York, USA; Department of Cell Biology, New York University Grossman School of Medicine, New York, New York, USA; Antimicrobial-Resistant Pathogens Program, New York University Langone Health, New York, New York, USA., Bhabha G; Department of Cell Biology, New York University Grossman School of Medicine, New York, New York, USA; Antimicrobial-Resistant Pathogens Program, New York University Langone Health, New York, New York, USA., Torres VJ; Department of Microbiology, New York University Grossman School of Medicine, New York, New York, USA; Department of Host-Microbe Interactions, St Jude Children's Research Hospital, Memphis, Tennessee, USA. Electronic address: victor.torres@stjude.org.

Publikováno v: The Journal of biological chemistry [J Biol Chem] 2023 Dec; Vol. 299 (12), pp. 105321. Date of Electronic Publication: 2023 Oct 04.

Characterization of Tigurilysin, a Novel Human CD59-Specific Cholesterol-Dependent Cytolysin, Reveals a Role for Host Specificity in Augmenting Toxin Activity.

Autor: Shahi I; New York University Grossman School of Medicine, Department of Pediatrics, New York, NY., Dongas SA; New York University Grossman School of Medicine, Department of Pediatrics, New York, NY., Ilmain JK; New York University Grossman School of Medicine, Department of Microbiology, New York, NY., Torres VJ; New York University Grossman School of Medicine, Department of Microbiology, New York, NY., Ratner AJ; New York University Grossman School of Medicine, Department of Pediatrics, New York, NY.; New York University Grossman School of Medicine, Department of Microbiology, New York, NY.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2023 Jul 25. Date of Electronic Publication: 2023 Jul 25.

MRSA lineage USA300 isolated from bloodstream infections exhibit altered virulence regulation.

Autor: Dyzenhaus S; Department of Microbiology, New York University Grossman School of Medicine, New York, NY 10016, USA., Sullivan MJ; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Alburquerque B; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Boff D; Department of Microbiology, New York University Grossman School of Medicine, New York, NY 10016, USA., van de Guchte A; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Chung M; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Fulmer Y; Division of Infectious Diseases and Immunology, Department of Medicine, New York University Grossman School of Medicine, New York, NY 10016, USA., Copin R; Division of Infectious Diseases and Immunology, Department of Medicine, New York University Grossman School of Medicine, New York, NY 10016, USA., Ilmain JK; Department of Microbiology, New York University Grossman School of Medicine, New York, NY 10016, USA., O'Keefe A; Department of Microbiology, New York University Grossman School of Medicine, New York, NY 10016, USA., Altman DR; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Division of Infectious Diseases, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Stubbe FX; Division of Infectious Diseases and Immunology, Department of Medicine, New York University Grossman School of Medicine, New York, NY 10016, USA., Podkowik M; Division of Infectious Diseases and Immunology, Department of Medicine, New York University Grossman School of Medicine, New York, NY 10016, USA., Dupper AC; Division of Infectious Diseases, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Shopsin B; Department of Microbiology, New York University Grossman School of Medicine, New York, NY 10016, USA; Division of Infectious Diseases and Immunology, Department of Medicine, New York University Grossman School of Medicine, New York, NY 10016, USA., van Bakel H; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Icahn Institute for Data Science and Genomic Technology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA. Electronic address: harm.vanbakel@mssm.edu., Torres VJ; Department of Microbiology, New York University Grossman School of Medicine, New York, NY 10016, USA. Electronic address: victor.torres@nyulangone.org.

Publikováno v: Cell host & microbe [Cell Host Microbe] 2023 Feb 08; Vol. 31 (2), pp. 228-242.e8. Date of Electronic Publication: 2023 Jan 20.

The Spike D614G mutation increases SARS-CoV-2 infection of multiple human cell types.

Autor: Daniloski Z; New York Genome Center, New York, United States.; Department of Biology, New York University, New York, United States., Jordan TX; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, United States., Ilmain JK; Department of Cell Biology and Skirball Institute of Biomolecular Medicine, New York University School of Medicine, New York, United States., Guo X; New York Genome Center, New York, United States.; Department of Biology, New York University, New York, United States., Bhabha G; Department of Cell Biology and Skirball Institute of Biomolecular Medicine, New York University School of Medicine, New York, United States., tenOever BR; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, United States., Sanjana NE; New York Genome Center, New York, United States.; Department of Biology, New York University, New York, United States.

Publikováno v: ELife [Elife] 2021 Feb 11; Vol. 10. Date of Electronic Publication: 2021 Feb 11.