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of 34
pro vyhledávání: '"Illingworth CJR"'
Strains of the influenza virus form coherent global populations, yet exist at the level of single infections in individual hosts. The relationship between these scales is a critical topic for understanding viral evolution. Here we investigate the wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::635c45585416412a7f0059ab8c3fd422
Autor:
Phonepadith Xangsayarath, Abhinay Ramaprasad, Arnab Pain, Kazuhide Yahata, Osamu Kaneko, Jianxia Tang, Richard Culleton, Mustonen, Jesse Gitaka, Richard Carter, Hayato Mitaka, Illingworth Cjr, Hussein M. Abkallo, Axel Martinelli, Augustin Zoungrana, Paul Hunt, Megumi Inoue
Identifying the genetic determinants of phenotypes that impact on disease severity is of fundamental importance for the design of new interventions against malaria. Traditionally, such discovery has relied on labor-intensive approaches that require s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eee1f6e164542344533152dfc536f707
Autor:
Domene, C, Illingworth, CJR
The von Hippel-Lindau tumor suppressor protein (pVHL) has an essential role in the regulation of the hypoxia response pathway in animal cells. Under normoxic conditions, the hypoxia-inducible factor (HIF) undergoes trans-4-prolyl hydroxylation and is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::c4b2a68d79b4322adaf55880fadc962e
https://doi.org/10.1002/prot.23230
https://doi.org/10.1002/prot.23230
Autor:
Illingworth, CJR
UNLABELLED: An increasingly common method for studying evolution is the collection of time-resolved short-read sequence data. Such datasets allow for the direct observation of rapid evolutionary processes, as might occur in natural microbial populati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______109::f3e54c3d8bd156f4fdec661df16193a6
https://www.repository.cam.ac.uk/handle/1810/255804
https://www.repository.cam.ac.uk/handle/1810/255804
Autor:
Sobel Leonard, A, McClain, MT, Smith, GJD, Wentworth, DE, Halpin, RA, Lin, X, Ransier, A, Stockwell, TB, Das, Gilbert, AS, Lambkin-Williams, R, Ginsburg, GS, Woods, CW, Koelle, K, Illingworth, CJR
We characterise the evolutionary dynamics of influenza infection described by viral sequence data collected from two challenge studies conducted in human hosts. Viral sequence data were collected at regular intervals from infected hosts. Changes in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0668da781060aa3517628c31bded8c36
Autor:
Abkallo, HM, Martinelli, A, Inoue, M, Ramaprasad, A, Xangsayarath, P, Gitaka, J, Tang, J, Yahata, K, Zoungrana, A, Mitaka, H, Acharjee, A, Datta, PP, Hunt, P, Carter, R, Kaneko, O, Mustonen, V, Illingworth, CJR, Pain, A, Culleton, R
Identifying the genetic determinants of phenotypes that impact disease severity is of fundamental importance for the design of new interventions against malaria. Here we present a rapid genome-wide approach capable of identifying multiple genetic dri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6d0dc7380a13b6c475f4ecf7a970140e
Autor:
Brock RC; MRC Biostatistics Unit, School of Clinical Medicine, University of Cambridge, Cambridge. UK., Goudie RJB; MRC Biostatistics Unit, School of Clinical Medicine, University of Cambridge, Cambridge. UK., Peters C; Department of Microbiology, NHS Greater Glasgow and Clyde, Glasgow, UK., Thaxter R; Infection Control, Cambridge University Hospitals, Cambridge. UK., Gouliouris T; Department of Infectious Diseases, Cambridge University Hospitals, Cambridge. UK; Department of Medicine, School of Clinical Medicine, University of Cambridge, Cambridge. UK., Illingworth CJR; MRC-University of Glasgow Centre for Virus Research, Glasgow., Morris AC; Department of Medicine, School of Clinical Medicine, University of Cambridge, Cambridge. UK; The John Farman ICU, Cambridge University Hospitals, Cambridge. UK., Beggs CB; Carnegie School of Sport, Headingley Campus, Leeds Beckett University, Leeds, UK; Department of Medicine for the Elderly, Cambridge University Hospitals, Cambridge. UK., Butler M; Department of Medicine for the Elderly, Cambridge University Hospitals, Cambridge. UK., Keevil VL; Department of Medicine, School of Clinical Medicine, University of Cambridge, Cambridge. UK; Department of Medicine for the Elderly, Cambridge University Hospitals, Cambridge. UK. Electronic address: v.keevil@nhs.net.
Publikováno v:
The Journal of hospital infection [J Hosp Infect] 2024 Oct 05. Date of Electronic Publication: 2024 Oct 05.
Autor:
Fozard JA; MRC-University of Glasgow Centre for Virus Research , Glasgow, UK., Thomson EC; MRC-University of Glasgow Centre for Virus Research , Glasgow, UK.; Department of Clinical Research, London School of Hygiene and Tropical Medicine , London, UK., Illingworth CJR; MRC-University of Glasgow Centre for Virus Research , Glasgow, UK.
Publikováno v:
Journal of the Royal Society, Interface [J R Soc Interface] 2024 Aug; Vol. 21 (217), pp. 20240168. Date of Electronic Publication: 2024 Aug 07.
Autor:
Sinclair P; MRC University of Glasgow Centre for Virus Research, Glasgow, UK., Zhao L; Section for GeoGenetics, Globe Institute, University of Copenhagen, Copenhagen, Denmark., Beggs CB; Carnegie School of Sport, Leeds Beckett University, Leeds, UK., Illingworth CJR; MRC University of Glasgow Centre for Virus Research, Glasgow, UK. christopher.illingworth@glasgow.ac.uk.
Publikováno v:
Nature communications [Nat Commun] 2024 Apr 26; Vol. 15 (1), pp. 3540. Date of Electronic Publication: 2024 Apr 26.
Autor:
Illingworth CJR; MRC-University of Glasgow Centre for Virus Research, 464 Bearsden Road, Glasgow G61 1QH, UK., Guerra-Assuncao JA; Great Ormond Street Hospital for Children NHS Foundation Trust, Great Ormond Street, London WC1N 3JH, UK.; Infection, Immunity and Inflammation Research and Teaching Department, University College London, Gower Street, London WC1E 6BT, UK., Gregg S; Infection, Immunity and Inflammation Research and Teaching Department, University College London, Gower Street, London WC1E 6BT, UK., Charles O; Great Ormond Street Hospital for Children NHS Foundation Trust, Great Ormond Street, London WC1N 3JH, UK.; Infection, Immunity and Inflammation Research and Teaching Department, University College London, Gower Street, London WC1E 6BT, UK., Pang J; Infection, Immunity and Inflammation Research and Teaching Department, University College London, Gower Street, London WC1E 6BT, UK., Roy S; Infection, Immunity and Inflammation Research and Teaching Department, University College London, Gower Street, London WC1E 6BT, UK., Abdelnabi R; KU Leuven Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, Herestraat 49, Leuven B-3000, Belgium.; The VirusBank Platform, Gaston Geenslaan, Leuven B-3000, Belgium., Neyts J; KU Leuven Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, Herestraat 49, Leuven B-3000, Belgium.; The VirusBank Platform, Gaston Geenslaan, Leuven B-3000, Belgium., Breuer J; Great Ormond Street Hospital for Children NHS Foundation Trust, Great Ormond Street, London WC1N 3JH, UK.; Infection, Immunity and Inflammation Research and Teaching Department, University College London, Gower Street, London WC1E 6BT, UK.
Publikováno v:
Virus evolution [Virus Evol] 2024 Jan 04; Vol. 10 (1), pp. veae001. Date of Electronic Publication: 2024 Jan 04 (Print Publication: 2024).