Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Ilko Stoytchev"'
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 2, Iss C (2013)
Nonviral gene delivery systems are rapidly becoming a desirable and applicable method to overexpress genes in various types of cells. We have recently developed a piggyBac transposase-based, helper-independent and self-inactivating delivery system (p
Externí odkaz:
https://doaj.org/article/3e3580d876684d818bb428e1ddd92d15
Publikováno v:
Synthetic Biology (Oxford, England)
Safer and more efficient methods for directing therapeutic genes to specific sequences could increase the repertoire of treatable conditions. Many current approaches act passively, first initiating a double-stranded break, then relying on host repair
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::388afb7c71bb87b3b36dbf8cb9246dcd
https://doi.org/10.1093/synbio/ysz018
https://doi.org/10.1093/synbio/ysz018
Autor:
Ilko Stoytchev, Mital S. Bhakta, David J. Segal, Damiano Mauro, Jesse B. Owens, Stefan Moisyadi, Moon-Soo Kim
Publikováno v:
Nucleic acids research, vol 41, iss 19
Nucleic Acids Research
Nucleic Acids Research
Insertional therapies have shown great potential for combating genetic disease and safer methods would undoubtedly broaden the variety of possible illness that can be treated. A major challenge that remains is reducing the risk of insertional mutagen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::549d7ad08cf3119910623aa97aeeec12
https://doi.org/10.1093/nar/gkt677
https://doi.org/10.1093/nar/gkt677
Autor:
Zoia Stoytcheva, Johann Urschitz, Kommineni J. Maragathavally, Jesse B. Owens, Stefan Moisyadi, Craig J. Coates, Mahdi Belcaid, David J. Segal, Nong C. Dang, Ilko Stoytchev
Publikováno v:
Nucleic acids research, vol 40, iss 14
Nucleic Acids Research
Nucleic Acids Research
Integrating vectors such as viruses and transposons insert transgenes semi-randomly and can potentially disrupt or deregulate genes. For these techniques to be of therapeutic value, a method for controlling the precise location of insertion is requir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccc8911058826ca802d30d154879b902
https://doi.org/10.1093/nar/gks309
https://doi.org/10.1093/nar/gks309
Autor:
Ryuzo Yanagimachi, Kris Kawamoto, Ilko Stoytchev, Hideaki Yamashiro, James A. Dee, Stefan Moisyadi, Joseph M. Kaminski, Joel Marh, Kazuto Morozumi, Johann Urschitz, Craig J. Coates, Pawel Pelczar, Jesse B. Owens, Miyuri Kawasumi
Publikováno v:
Proceedings of the National Academy of Sciences. 107:8117-8122
Efficient integration of functional genes is an essential prerequisite for successful gene delivery such as cell transfection, animal transgenesis, and gene therapy. Gene delivery strategies based on viral vectors are currently the most efficient. Ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d39430fd453b5a0c57fc8c148a0e325
https://doi.org/10.1073/pnas.1003674107
https://doi.org/10.1073/pnas.1003674107
Publikováno v:
Molecular and Cellular Biology. 27:7848-7855
Selenoprotein mRNAs are potential targets for degradation via nonsense-mediated decay due to the presence of in-frame UGA codons that can be decoded as either selenocysteine or termination codons. When UGA decoding is inefficient, as occurs when sele
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6237cb9f1fcf78d75d32f116082f7918
https://doi.org/10.1128/mcb.00793-07
https://doi.org/10.1128/mcb.00793-07
Autor:
Tomáš Cajthaml, F. Nerud, Ilko Stoytchev, Pavel Stopka, Věra Merhautová, Petr Baldrian, Pradeep Verma, Ivana Eichlerová, Tomáš Trnka, Jiří Gabriel
Publikováno v:
Applied Catalysis B: Environmental. 51:159-164
Copper(II) or cobalt(II)/ligand/hydrogen peroxide systems were used for degradation of benzene, toluene, ethylbenzene, xylenes (BTEX), and polycylic aromatic hydrocarbons. The most efficient systems were Cu/glucaric acid/H2O2 and Cu/ d -arabinono-1,4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8cbb0bffee27308cc33b95034e28a034
https://doi.org/10.1016/j.apcatb.2004.02.011
https://doi.org/10.1016/j.apcatb.2004.02.011
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 2, Iss C (2013)
Molecular Therapy. Nucleic Acids
Molecular Therapy. Nucleic Acids
Nonviral gene delivery systems are rapidly becoming a desirable and applicable method to overexpress genes in various types of cells. We have recently developed a piggyBac transposase-based, helper-independent and self-inactivating delivery system (p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5d0187b01709ece9dafc135cef88c3f
Autor:
Jesse B. Owens, Ryuzo Yanagimachi, Atsushi Sugawara, Pawel Pelczar, Joel Marh, Johann Urschitz, Zoia Stoytcheva, Hideaki Yamashiro, Stefan Moisyadi, Ilko Stoytchev
We have developed a unique method for mouse transgenesis. The transposase-enhanced pronuclear microinjection (PNI) technique described herein uses the hyperactive piggyBac transposase to insert a large transgene into the mouse genome. This procedure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c28a7e83c7d8d32cb5b9eedb6350743
https://europepmc.org/articles/PMC3511126/
https://europepmc.org/articles/PMC3511126/
Publikováno v:
Antonie van Leeuwenhoek. 79:363-364
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::60658b7a17f15766592d0ec2bffddce5
https://doi.org/10.1023/a:1012049109035
https://doi.org/10.1023/a:1012049109035