Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Ilkka Ketola"'
Autor:
Virve Pentikäinen, Minna Eriksson, Leo Dunkel, Riina Oksjoki, Kimmo Taari, Krista Erkkilä, Markku Heikinheimo, Ilkka Ketola, Laura Suomalainen
Publikováno v:
MHR: Basic science of reproductive medicine. 10:743-753
Apoptosis limits germ cell number in the testis, and its dysregulation is associated with male infertility. Here, we evaluated the role of the transcription factor activator protein 1 (AP-1) in male germ cell apoptosis in a culture of human seminifer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf1757c32208f1f98576ad2e8284d1a5
https://doi.org/10.1093/molehr/gah094
https://doi.org/10.1093/molehr/gah094
Autor:
Hannele Niemi, Markku Heikinheimo, Mari-Anne Pulkkinen, Jaan Palgi, Ilkka Ketola, Timo Otonkoski, David B. Wilson, Christina Jacobsen
Publikováno v:
Molecular and Cellular Endocrinology. 226:51-57
GATA-4 and GATA-6 are zinc finger transcription factors that regulate gene expression, differentiation, and cell proliferation in various tissues. These factors have been implicated in the development of endodermal derivatives, including epithelial c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a8edf9d67a19b672767b62e9de608a8
https://doi.org/10.1016/j.mce.2004.06.007
https://doi.org/10.1016/j.mce.2004.06.007
Publikováno v:
Biology of Reproduction. 68:1333-1340
Transcription factor GATA-4 has been suggested to have a role in mammalian gonadogenesis, e.g., through activation of the Mullerian-inhibiting substance (MIS) gene expression. Although the expression of GATA-4 during gonadogenesis has been elucidated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9a4c93f3e8bcfbe4a22e9e45cc2f9839
https://doi.org/10.1095/biolreprod.102.008599
https://doi.org/10.1095/biolreprod.102.008599
Autor:
Juha S. Tapanainen, Tommi E. Vaskivuo, Markku Heikinheimo, Jorma Toppari, Ilkka Ketola, Mikko Anttonen
Publikováno v:
European Journal of Endocrinology. :397-406
OBJECTIVE: The transcription factors GATA-1 and GATA-4 have been implicated in the regulation of testicular development and function. Their cofactors FOG-1 and FOG-2 are expressed in the gonads, but their cell-specific and developmental expression in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9500adacf14325797ee7fc9bcd249fca
https://doi.org/10.1530/eje.0.1470397
https://doi.org/10.1530/eje.0.1470397
Autor:
Juha S. Tapanainen, Virve Pentikäinen, Leo Dunkel, Jorma Toppari, Ilkka Ketola, Markku Heikinheimo, V Ilvesmäki, Riitta Herva, Tommi E. Vaskivuo
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 85:3925-3931
GATA-4 is a highly conserved transcription factor that plays a critical role in regulating embryonic morphogenesis and cellular differentiation. Given the emerging role of GATA-4 in the development and function of murine gonads, we have now studied i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b9b6ac07ad1565d3e821acec2f724b8
https://doi.org/10.1210/jcem.85.10.6900
https://doi.org/10.1210/jcem.85.10.6900
Autor:
Ilkka Ketola, Ralf Bützow, Olli Ritvos, Mika Laitinen, David B. Wilson, Mikko Anttonen, Markku Heikinheimo
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 85:3476-3483
Previous studies have implicated transcription factors GATA-4 and GATA-6 in the regulation of murine ovarian development and function. In rodents, GATA-4 is expressed in granulosa cells of primary and early antral follicles, whereas GATA-6 is express
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afd410c970521ba9d67ed31f368ad390
https://doi.org/10.1210/jcem.85.9.6828
https://doi.org/10.1210/jcem.85.9.6828
Autor:
Jorma Toppari, Nafis A. Rahman, Juha S. Tapanainen, David B. Wilson, Ilkka Ketola, Ilpo Huhtaniemi, Markku Heikinheimo, Susan B. Porter-Tinge, Malgorzata Bielinska
Publikováno v:
Endocrinology. 140:1470-1480
Previous studies have shown that transcription factors GATA-4 and GATA-6 are expressed in granulosa and thecal cells of the mouse ovary and that GATA-4 expression in ovarian tissue is regulated by gonadotropins. Given the emerging role of GATA-4 and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d4dd5172b92260a8fb025dc6932386c
https://doi.org/10.1210/endo.140.3.6587
https://doi.org/10.1210/endo.140.3.6587
Autor:
Markku Heikinheimo, Juha S. Tapanainen, Jorma Toppari, Ilkka Ketola, Riitta Herva, Tommi E. Vaskivuo
Publikováno v:
The Journal of clinical endocrinology and metabolism. 88(4)
The GATA family of transcription factors have been implicated in regulating the development and function of many organs. Furthermore, they have been linked to signaling cascades regulating cell fate through apoptosis. GATA-6 has been shown to be expr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::054314dc2943338ea92f705dfa2868c9
https://pubmed.ncbi.nlm.nih.gov/12679484
https://pubmed.ncbi.nlm.nih.gov/12679484
Publikováno v:
Biology of reproduction. 68(4)
Transcription factor GATA-4 has been suggested to have a role in mammalian gonadogenesis, e.g., through activation of the Müllerian-inhibiting substance (MIS) gene expression. Although the expression of GATA-4 during gonadogenesis has been elucidate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5784aeec6acb2298acf6b91734a53e29
https://pubmed.ncbi.nlm.nih.gov/12606418
https://pubmed.ncbi.nlm.nih.gov/12606418
Publikováno v:
The Journal of clinical endocrinology and metabolism. 86(4)
Prostaglandins (PGs) have been implicated in regulation of ovarian function. We have previously shown that the expression of cyclooxygenase-2 and the receptor for PGF(2 alpha) are expressed in periovulatory human granulosa cells and upregulated by go
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7ddd53e1e3d822ae9a9c7be855fe061
https://pubmed.ncbi.nlm.nih.gov/11297615
https://pubmed.ncbi.nlm.nih.gov/11297615