Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Ilke Sen"'
Autor:
Emmanuelle Charrin, Dina Dabaghie, Ilke Sen, David Unnersjö-Jess, Katja Möller-Hackbarth, Mikhail Burmakin, Rik Mencke, Sonia Zambrano, Jaakko Patrakka, Hannes Olauson
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-16 (2023)
Transgenic overexpression of αKlotho in hepatocytes results in protection against renal insults, possibly through modulation of the ER stress response by circulating αKlotho. In contrast, αKlotho overexpressed in podocytes is not renoprotective.
Externí odkaz:
https://doaj.org/article/619b3e82d9e24b86ae6db800031da9d4
Autor:
Ilke Sen, Xin Zhou, Alexey Chernobrovkin, Nataly Puerta-Cavanzo, Takaharu Kanno, Jérôme Salignon, Andrea Stoehr, Xin-Xuan Lin, Bora Baskaner, Simone Brandenburg, Camilla Björkegren, Roman A. Zubarev, Christian G. Riedel
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
The transcription factor DAF-16/FOXO mediates a wide variety of aging-preventive responses by driving the expression of stress resistance and longevity promoting genes. Here the authors show that transcriptional initiation at many DAF-16/FOXO target
Externí odkaz:
https://doaj.org/article/8a70884b9ec74e81afa962b134fef5ad
Autor:
Tamara Casteels, Yufeng Zhang, Thomas Frogne, Caterina Sturtzel, Charles-Hugues Lardeau, Ilke Sen, Xiaocheng Liu, Shangyu Hong, Florian M. Pauler, Thomas Penz, Marlene Brandstetter, Charlotte Barbieux, Ekaterine Berishvili, Thomas Heuser, Christoph Bock, Christian G. Riedel, Dirk Meyer, Martin Distel, Jacob Hecksher-Sørensen, Jin Li, Stefan Kubicek
Publikováno v:
Molecular Metabolism, Vol 54, Iss , Pp 101329- (2021)
Objective: The loss of forkhead box protein O1 (FoxO1) signaling in response to metabolic stress contributes to the etiology of type II diabetes, causing the dedifferentiation of pancreatic beta cells to a cell type reminiscent of endocrine progenito
Externí odkaz:
https://doaj.org/article/a0e438a3cef045b6a78157d78619e54d
Autor:
Xin-Xuan Lin, Ilke Sen, Georges E. Janssens, Xin Zhou, Bryan R. Fonslow, Daniel Edgar, Nicholas Stroustrup, Peter Swoboda, John R. Yates, Gary Ruvkun, Christian G. Riedel
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
The transcription factor DAF-16/FOXO is a downstream effector of insulin/insulin-like growth factor signaling and plays an important role in stress resistance and longevity. Here, the authors show that DAF-16/FOXO can form a complex with HLH-30/TFEB
Externí odkaz:
https://doaj.org/article/560c3b80b1d74b0b81296e799f7bb7fb
Autor:
Georges E. Janssens, Xin-Xuan Lin, Lluís Millan-Ariño, Alan Kavšek, Ilke Sen, Renée I. Seinstra, Nicholas Stroustrup, Ellen A.A. Nollen, Christian G. Riedel
Publikováno v:
Cell Reports, Vol 27, Iss 2, Pp 467-480.e6 (2019)
Summary: Aging strongly influences human morbidity and mortality. Thus, aging-preventive compounds could greatly improve our health and lifespan. Here we screened for such compounds, known as geroprotectors, employing the power of transcriptomics to
Externí odkaz:
https://doaj.org/article/0f0d00ea6e6e44599aab71af29fa6f74
Autor:
Ebru Umay, Sibel Eyigor, Gulistan Bahat, Meltem Halil, Esra Giray, Pelin Unsal, Zeliha Unlu, Canan Tikiz, Meltem Vural, Asli Tufan Cincin, Serkan Bengisu, Eda Gurcay, Kemal Keseroglu, Banu Aydeniz, Elif Celik Karaca, Burak Karaca, Ahmet Yalcin, Cemile Ozsurekci, Dilek Seyidoglu, Ozlem Yilmaz, Sibel Alicura, Serhat Tokgoz, Barin Selcuk, Ekin Ilke Sen, Ali Yavuz Karahan, Ayse Yaliman, Serdar Ozkok, Birkan Ilhan, Merve Guner Oytun, Zeynel Abidin Ozturk, Sibel Akin, Betul Yavuz, Mazlum Serdar Akaltun, Aylin Sari, Murat Inanir, Meral Bilgilisoy, Zuhal Çaliskan, Guleser Saylam, Tugce Ozer, Yasemin Eren, Derya Hopanci Bicakli, Dilek Keskin, Zekeriya Ulger, Aylin Demirhan, Yalkin Calik, Bulent Saka, Zeynep Aykin Yigman, Erhan Arif Ozturk
Background: Dysphagia is a geriatric syndrome. Changes in the whole body that occur with aging also affect swallowing functions and cause presbyphagia. This condition may progress to oropharyngeal and/or esophageal dysphagia in the presence of second
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31a49f15c1c3765f0477be0f2f19007e
https://hdl.handle.net/11424/282114
https://hdl.handle.net/11424/282114
Autor:
Fatih Karaahmet, Nefati Kiylioglu, Eda Gurcay, Canan Tikiz, Ayşe Yaliman, Aylin Sari, Banu Aydeniz, Meral Bilgilisoy, Cumhur Ertekin, Mehmet Fevzi Oztekin, Güleser Saylam, Zeynep Alev Ozcete, Ebru Umay, Arif Yüksel, Mazlum Serdar Akaltun, Yaprak Seçil, Ilknur Albayrak Gezer, Sevnaz Şahin, Aylin Demirhan, Tanu Yalcin Gokler, Meltem Vural, Barin Selcuk, Ali Yavuz Karahan, Murat Inanir, Yalkın Calik, Gulistan Bahat, Serkan Bengisu, Ebru Alemdaroğlu, Sibel Eyigör, Serdar Mercimekci, Betul Yavuz Keles, Özgür Zeliha Karaahmet, Esra Giray, Ekin Ilke Sen, Baha Sezgin, Sibel Alicura, Zeliha Unlu, Dilek Keskin
Publikováno v:
Dysphagia. 37:217-236
Dysphagia is one of the most common and important complications of stroke. It is an independent marker of poor outcome after acute stroke and may become chronic after the acute period and continues to affect all aspects of the patient's life. Patient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c24a32884b125115d3b7c8beb907fdf1
https://doi.org/10.1007/s00455-021-10273-9
https://doi.org/10.1007/s00455-021-10273-9
Publikováno v:
Acta Orthop Traumatol Turc
Acta Orthopaedica et Traumatologica Turcica, Vol 54, Iss 5, Pp 502-506 (2020)
Acta Orthopaedica et Traumatologica Turcica, Vol 54, Iss 5, Pp 502-506 (2020)
OBJECTIVE: This study aimed to determine the effects of the microprocessor-controlled prosthetic knee (MPK) joint on self-mobility, body perceptions, depression, and quality of life in patients with unilateral transfemoral amputations (TFAs). METHODS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc41802669c709a025ca1a89d0e52d54
https://doi.org/10.5152/j.aott.2020.19269
https://doi.org/10.5152/j.aott.2020.19269
Autor:
Demirhan Diracoglu, Fatma Nur Kesiktas, Mustafa Aziz Yildirim, Tugba Yesilyurt, Ekin Ilke Sen
Publikováno v:
Journal of Back and Musculoskeletal Rehabilitation. 33:597-605
The interest in biological treatments that have the potential to modify cartilage biology has gradually increased in recent years.The aim of our study was to investigate the effects of intra-articular platelet-rich plasma (IA-PRP) injections on the f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c3517ab1034119a00469ee5741786a3
https://doi.org/10.3233/bmr-181209
https://doi.org/10.3233/bmr-181209
Autor:
Fatma Nur Kesiktas, Bahar Dernek, Ekin Ilke Sen, Tugba Aydin, Havva Nur Albayrak, Merve Beyza Yildiz
Publikováno v:
Clinical Rheumatology
Introduction/objectives Intra-articular injections may be useful in terms of pain and functional status, in knee osteoarthritis (OA). Besides hyaluronic acid (HA) and platelet-rich plasma (PRP), peptide molecules recently begin to be used. The aim of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::503cd368d5f118f4bf45a2149fa4ebb2
https://doi.org/10.1007/s10067-020-05121-4
https://doi.org/10.1007/s10067-020-05121-4