Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Ilkay Evren"'
Autor:
Ruud H. Brakenhoff, Elisabeth Bloemena, Jan G.A.M. de Visscher, Elisabeth R. Brouns, Ilkay Evren, Arjen Brink, Jos B. Poell, Leon J. Wils
Overview of type of changes found in 12 target genes in 89 OL samples. Top: In the left graph the distribution of the classes of mutations is depicted. In the middle graph the type of variants is shown. In the right graph the nucleotide changes are i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::091508a7cb09c56ebae01960c3cac468
https://doi.org/10.1158/1078-0432.22490488.v1
https://doi.org/10.1158/1078-0432.22490488.v1
Autor:
Ruud H. Brakenhoff, Elisabeth Bloemena, Jan G.A.M. de Visscher, Elisabeth R. Brouns, Ilkay Evren, Arjen Brink, Jos B. Poell, Leon J. Wils
Copy number profiles and mutations for biopsies from the oral leukoplakia and the tumor from two patients that have a different origin. For each lesion the location, the copy number profile and the mutations are shown. For each mutation the gene, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d252457be111a18a42a592e5edfdd02
https://doi.org/10.1158/1078-0432.22490491
https://doi.org/10.1158/1078-0432.22490491
Autor:
Ruud H. Brakenhoff, Elisabeth Bloemena, Jan G.A.M. de Visscher, Elisabeth R. Brouns, Ilkay Evren, Arjen Brink, Jos B. Poell, Leon J. Wils
Overview of Kaplan-Meier curves for several investigated genetic markers in 89 OL samples. On the y-axis the fraction remaining free of malignant transformation over time is shown. The x-axis shows the time in years. The table below the figure specif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3927c7f7a25dce478209ff006597f259
https://doi.org/10.1158/1078-0432.22490515.v1
https://doi.org/10.1158/1078-0432.22490515.v1
Autor:
Ruud H. Brakenhoff, Elisabeth Bloemena, Jan G.A.M. de Visscher, Elisabeth R. Brouns, Ilkay Evren, Arjen Brink, Jos B. Poell, Leon J. Wils
Overview of laboratory methods for the processing of oral leukoplakia biopsies for next generation sequencing.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bac2a6ceb04040b710a2e7fc4c687d1
https://doi.org/10.1158/1078-0432.22490506.v1
https://doi.org/10.1158/1078-0432.22490506.v1
Autor:
Ruud H. Brakenhoff, Elisabeth Bloemena, Jan G.A.M. de Visscher, Elisabeth R. Brouns, Ilkay Evren, Arjen Brink, Jos B. Poell, Leon J. Wils
Overview of CNA’s found in a cohort of 312 OSCC samples obtained from the TCGA database. Frequency of gains (in blue) and losses (in red) for the entire cohort are shown on the y-axis. Chromosomes are shown on the x-axis. Top 5 most frequently affe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::570939c8cc4ed1b6ef4652124752031e
https://doi.org/10.1158/1078-0432.22490482.v1
https://doi.org/10.1158/1078-0432.22490482.v1
Autor:
Ruud H. Brakenhoff, Elisabeth Bloemena, Jan G.A.M. de Visscher, Elisabeth R. Brouns, Ilkay Evren, Arjen Brink, Jos B. Poell, Leon J. Wils
Overview of the inclusion of patient samples from the consecutive oral leukoplakia cohort. lcWGS = Low coverage whole genome sequencing.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75091fc3a9b076f77cd212f58af255c5
https://doi.org/10.1158/1078-0432.22490518.v1
https://doi.org/10.1158/1078-0432.22490518.v1
Autor:
Ruud H. Brakenhoff, Elisabeth Bloemena, Jan G.A.M. de Visscher, Elisabeth R. Brouns, Ilkay Evren, Arjen Brink, Jos B. Poell, Leon J. Wils
Purpose:Oral leukoplakia is the most common oral potentially malignant disorder with an annual malignant transformation rate of 1% to 5%. Consequently, oral leukoplakia patients have a 30% to 50% lifetime risk to develop oral squamous cell carcinoma.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49789096e232b84418bdbdaeb0920098
https://doi.org/10.1158/1078-0432.c.6533164
https://doi.org/10.1158/1078-0432.c.6533164
Autor:
Ruud H. Brakenhoff, Elisabeth Bloemena, Jan G.A.M. de Visscher, Elisabeth R. Brouns, Ilkay Evren, Arjen Brink, Jos B. Poell, Leon J. Wils
Overview of the number of CNAs and time to progression for each of the 25 progressors. The top bars show the number of CNAs. The bottom bars show the time to progression in months. CNAs = copy number aberrations.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27db79432571e72ee76e7bad58eee695
https://doi.org/10.1158/1078-0432.22490485.v1
https://doi.org/10.1158/1078-0432.22490485.v1
Autor:
Ruud H. Brakenhoff, Elisabeth Bloemena, Jan G.A.M. de Visscher, Elisabeth R. Brouns, Ilkay Evren, Arjen Brink, Jos B. Poell, Leon J. Wils
Kaplan-Meier curves for the malignant transformation-free survival of the 89 oral leukoplakia patients in the study stratified by presence of classic or any dysplasia (including differentiated dysplasia). On the y-axis the fraction remaining free of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d4db1f0ffc9b4abbef1c4aa69757fcc
https://doi.org/10.1158/1078-0432.22490494.v1
https://doi.org/10.1158/1078-0432.22490494.v1
Autor:
Ruud H. Brakenhoff, Elisabeth Bloemena, Jan G.A.M. de Visscher, Elisabeth R. Brouns, Ilkay Evren, Arjen Brink, Jos B. Poell, Leon J. Wils
Forest plot containing all markers included in the final prediction model after step-wise selection for all oral leukoplakias with presence of dysplasia in 63 OL samples. Each row represents one variable. The first column shows the assessed marker. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b2d38958de1a62ec19e0d1a8be1fa8e
https://doi.org/10.1158/1078-0432.22490509.v1
https://doi.org/10.1158/1078-0432.22490509.v1