Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Ilka Wagner"'
Publikováno v:
Journal of Biotechnology. 152:108-112
Across many tissues and organs, the ability to create an organoid, the smallest functional unit of an organ, in vitro is the key both to tissue engineering and preclinical testing regimes. The hair follicle is an organoid that has been much studied b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f09b2636a742b6c22129c37bf3804a3
https://doi.org/10.1016/j.jbiotec.2011.01.019
https://doi.org/10.1016/j.jbiotec.2011.01.019
Autor:
Jasmin Gattlen, Richa Gautam, Tamara Atanasova, Ilka Wagner, Markus Rimann, Ursula Graf-Hausner, Epifania Bono, Ralf Pörtner, Uwe Marx
o Der Bedarf an Testsystemen fur chemische und pharmakologisch aktive Substanzen ist aufgrund regulatorischer Vorgaben (EU-Chemikalienverordnung REACH, Kosmetikverordnung) immens gestiegen. Anstelle der heute noch ublichen Tierversuche sollen kunftig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bdc5653c6d5bf63e7d7289800e63194
Autor:
Uwe Marx, Gerd Lindner, Ilka Wagner, Beren Atac, Reyk Horland, Reza P. Azar, Alexander G. Tonevitsky, Roland Lauster
Publikováno v:
Lab on a chip. 13(18)
Dieser Beitrag ist mit Zustimmung des Rechteinhabers aufgrund einer (DFG geförderten) Allianz- bzw. Nationallizenz frei zugänglich. This publication is with permission of the rights owner freely accessible due to an Alliance licence and a national
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41c19fd5fad999b1a7d7774f620e6a42
https://pubmed.ncbi.nlm.nih.gov/23674126
https://pubmed.ncbi.nlm.nih.gov/23674126
Autor:
Udo Klotzbach, Gerd Lindner, Beren Atac, Uwe Marx, Frank Sonntag, Ilka Wagner, M. Gruchow, Roland Lauster, Silke Hoffmann, Reyk Horland
Publikováno v:
BMC Proceedings, Vol 5, Iss Suppl 8, p O7 (2011)
BMC Proceedings
BMC Proceedings
The ability to create an organoid, the smallest functional unit of an organ, in vitro across many human tissues and organs is the key to both efficient transplant generation and predictive preclinical testing regimes. The hair follicle is an organoid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e58752d211819f1fed6ccd653fb9dc45
https://doaj.org/article/a3274d7a3ded4bd1b4b602a3319fe629
https://doaj.org/article/a3274d7a3ded4bd1b4b602a3319fe629
Weder die zwei organtypischen statischen Epidermis-Kurzzeitmodelle noch das etablierte humane statische Hautmodell eignen sich für eine aussagekräftige Langzeittestung von Substanzen mit wiederholter Exposition auf Toxizität und Hautpenetration. D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a0cbed0e50526525d12b76703e2bc82
https://publica.fraunhofer.de/handle/publica/225442
https://publica.fraunhofer.de/handle/publica/225442
Autor:
Katja Mader, Udo Klotzbach, Uwe Marx, Mathias Gruchow, Roland Lauster, Gerd Lindner, Steffen Howitz, Silke Hoffmann, Reyk Horland, Frank Sonntag, Ilka Wagner, Niels Schilling
Dynamic miniaturized human multi-micro-organ bioreactor systems are envisaged as a possible solution for the embarrassing gap of predictive substance testing prior to human exposure. A rational approach was applied to simulate and design dynamic long
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3ab3bb7ff6b47a17b4c73c5d14ebc2c
https://publica.fraunhofer.de/handle/publica/222149
https://publica.fraunhofer.de/handle/publica/222149
Autor:
Tobias Hasenberg, Alexandra Lorenz, Eva-Maria Materne, Roland Lauster, Reyk Horland, Katharina Schimek, Uwe Marx, Frank Sonntag, Ilka Wagner, Annika Jaenicke, Anja Patricia Ramme
Publikováno v:
Toxicology Letters. 229:S139
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ddb22aaeac142c029802eba78a396d42
https://doi.org/10.1016/j.toxlet.2014.06.490
https://doi.org/10.1016/j.toxlet.2014.06.490
Autor:
Mathias Busek, Alexandra Lorenz, Caroline Frädrich, Udo Klotzbach, Roland Lauster, Reyk Horland, Silke Hoffmann, Uwe Marx, Eva-Maria Materne, Frank Sonntag, Ilka Wagner, Sven Brincker
Publikováno v:
BMC Proceedings
Background The ever-growing amount of new substances released to the market and the limited predictability of current in vitro test systems has led to an ample need for new substance testing solutions. Many drugs like troglitazone, that had to be rem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af56ced8d80227249744272c5bf83603
http://europepmc.org/articles/PMC3980301
http://europepmc.org/articles/PMC3980301
Autor:
Silke Hoffmann, Alexandra Lorenz, Reyk Horland, Udo Klotzbach, Frank Sonntag, Gerd Lindner, Ulrike Menzel, Ilka Wagner, Uwe Marx, Benjamin Groth, Mathias Busek, Roland Lauster, Sven Brincker, Katharina Schimek, Eva-Maria Materne
Publikováno v:
BMC Proceedings
Background Enormous efforts have been made to develop circulation systems for physiological nutrient supply and waste removal of in vitro cultured tissues. These developments are aiming for in vitro generation of organ equivalents such as liver, lymp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::046434b5700d297547d11dd1612a941a
http://europepmc.org/articles/PMC3980705
http://europepmc.org/articles/PMC3980705
Autor:
Alexander G. Tonevitsky, Mathias Busek, Sven Brincker, Ute Süßbier, Frank Sonntag, Ilka Wagner, E. V. Trushkin, Uwe Marx, Caroline Frädrich, Eva-Maria Materne, Roland Lauster, D. A. Sakharov
Publikováno v:
Lab on a Chip. 13:3538
Current in vitro and animal tests for drug development are failing to emulate the systemic organ complexity of the human body and, therefore, to accurately predict drug toxicity. In this study, we present a multi-organ-chip capable of maintaining 3D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::040356b3af2ea029f6d4aaba776e4b1b
https://doi.org/10.1039/c3lc50234a
https://doi.org/10.1039/c3lc50234a