Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Ilja Tabujew"'
Autor:
Ilja Tabujew, Kaloian Koynov, Nadine Leber, Mark Helm, Christoph Freidel, Inka Negwer, Kalina Peneva, Katharina Landfester, Marleen Willig, Volker Mailänder, Rudolf Zentel
Publikováno v:
Acta Biomaterialia. 100:338-351
Bioengineering immune cells via gene therapy offers treatment opportunities for currently fatal viral infections. Also cell therapeutics offer most recently a breakthrough technology to combat cancer. These primary human cells, however, are sensitive
Autor:
Maziar Heidari, Raffaello Potestio, Kerstin Nagel-Wolfrum, Kaloian Koynov, Christoph Freidel, Philip Biehl, Ilja Tabujew, Lars Tebbe, Kalina Peneva, Uwe Wolfrum, Mark Helm, Felix H. Schacher
Publikováno v:
Biomacromolecules. 20:4389-4406
Despite the first successful applications of nonviral delivery vectors for small interfering RNA in the treatment of illnesses, such as the respiratory syncytial virus infection, the preparation of a clinically suitable, safe, and efficient delivery
Autor:
Ulrich S. Schubert, Kalina Peneva, Dagmar Fischer, Leon Zartner, Ceren Cokca, Ilja Tabujew, Ivo Nischang
Publikováno v:
Journal of Materials Chemistry B. 7:5920-5929
Herein, we report the first gradient guanidinium containing cationic copolymers and investigate their binding ability to plasmid DNA (pDNA). To understand the effect of different charge distributions and cationic charge sources (primary amines vs. gu
Autor:
Ilja Tabujew, Stefka Kaloyanova, Kalina Peneva, Alexander Schramm, Christoph Freidel, Klaus Müllen, Marco Lelle, Michael U. Musheev, Christof Niehrs
Publikováno v:
European Journal of Medicinal Chemistry. 130:336-345
We describe the synthesis and characterization of a novel bioconjugate, consisting of an octaarginine cell-penetrating peptide and a highly DNA-affine doxorubicin dimer. The linkage between the two components is composed of a cleavable disulfide bond
Publikováno v:
Biosensorsbioelectronics. 104
A novel detection platform with high malathion specificity has been developed, which operates based on the signal response in the fluorescence of CdTe@CdS quantum dots (QDs). The designed nanoprobe comprises of QDs, poly(N-(3-guanidinopropyl)methacry
Autor:
Ilja, Tabujew, Marleen, Willig, Nadine, Leber, Christoph, Freidel, Inka, Negwer, Kaloian, Koynov, Mark, Helm, Katharina, Landfester, Rudolf, Zentel, Kalina, Peneva, Volker, Mailänder
Publikováno v:
Acta biomaterialia. 100
Bioengineering immune cells via gene therapy offers treatment opportunities for currently fatal viral infections. Also cell therapeutics offer most recently a breakthrough technology to combat cancer. These primary human cells, however, are sensitive
Autor:
Markus Hirsch, Wolfgang Tremel, Manfred Schmidt, Ilja Tabujew, Bettina Krieg, Heiko Bauer, Sandra Decker, Mark Helm, Andriy Khobta, Kaloian Koynov, Erik Scholz, Lutz Nuhn, Kalina Peneva, A. James Mason, Rudolf Zentel
Publikováno v:
Pharmaceutical Research. 32:1957-1974
Release of siRNA from nanoscale polyplexes is a crucial yet little investigated process, important during all stages of therapeutic research. Here we develop new methods to characterize polyplex stability early on in the development of new materials.
Publikováno v:
BioNanoMaterials. 16
More than two decades ago, a group of peptides, now known as cell-penetrating peptides, sparked the hope that the ultimate carrier molecules have been found. The high expectations for these peptides, which are reflected in their bold name, led to man
Autor:
Ilja Tabujew, Kalina Peneva
Publikováno v:
Cationic Polymers in Regenerative Medicine ISBN: 9781849739375
Cationic polymers have attracted tremendous attention in recent years as non-viral vectors in gene delivery, owing to their high cellular uptake efficiency, good water solubility, excellent transfection efficiencies and facile synthesis. These polyme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::38dc9322fdd29dc55f1ba423e0fb6168
https://doi.org/10.1039/9781782620105-00001
https://doi.org/10.1039/9781782620105-00001
Autor:
Bettina Krieg, Ilja Tabujew, Kalina Peneva, Kaloian Koynov, Klaus Müllen, Christoph Freidel, Mark Helm
Publikováno v:
Macromolecular rapid communications. 35(13)
Here, the preparation of a novel block copolymer consisting of a statistical copolymer N-(2-hydroxypropyl) methacrylamide-s-N-(3-aminopropyl) methacrylamide and a short terminal 3-guanidinopropyl methacrylamide block is reported. This polymer structu