Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Ilja Bobylev"'
Autor:
Ilja Bobylev, Abhijeet R. Joshi, Mohammed Barham, Christian Ritter, Wolfram F. Neiss, Ahmet Höke, Helmar C. Lehmann
Publikováno v:
Neurobiology of Disease, Vol 82, Iss , Pp 321-331 (2015)
Paclitaxel is an integral component of solid tumor treatment. This chemotherapeutic agent provokes an often irreversible peripheral sensory neuropathy with pathological features of distal axonal degeneration. Current pathological concepts assume that
Externí odkaz:
https://doaj.org/article/675f3519d420486787f49c96e3f94103
Autor:
Gang Zhang, Ilja Bobylev, Kazim A. Sheikh, Martin K.R. Svačina, Philip Röth, Alina Sprenger, Helmar C. Lehmann
Publikováno v:
Journal of Neuroimmune Pharmacology. 14:642-648
Intravenous immunoglobulins (IVIg) are standard treatment for Guillain-Barré syndrome (GBS). Their exact mechanisms of action are versatile and not fully understood. One possible mechanism is neutralization of circulating autoantibodies via binding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a04f803fd1f6b50513f592d9e691cf10
https://doi.org/10.1007/s11481-019-09871-0
https://doi.org/10.1007/s11481-019-09871-0
Autor:
Man Mohan Mehndiratta, Martin K.R. Svačina, Christian A. Vedeler, Abhijeet R. Joshi, Yogesh Sharma, Helmar C. Lehmann, Ilja Bobylev, Hauke Wüstenberg, Gina Remke, Ines Klein, Alina Sprenger
Publikováno v:
Journal of the neurological sciences. 427
Chronic inflammatory demyelinating polyneuropathy (CIDP) is an autoimmune disorder causing inflammatory demyelination of peripheral nerves and consecutive disability. Diagnostic criteria and treatments are well established, but it is unknown how clin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05598280f4178e01e612192aae2de856
https://pubmed.ncbi.nlm.nih.gov/34130060
https://pubmed.ncbi.nlm.nih.gov/34130060
Autor:
Ilja Bobylev, Abhijeet R. Joshi, Martin H. J. Wiesen, Ines Klein, Virginia Albert, Carsten Müller, Helmar C. Lehmann
Publikováno v:
Journal of the peripheral nervous system : JPNSREFERENCES. 26(2)
Background and aims Peripheral neuropathy is a common side effect of paclitaxel. Clinical studies suggest that different paclitaxel formulations influence the severity and time course of paclitaxel-induced peripheral neuropathy. We compared two pacli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::507d82736189aa11a41efa1e4fe713a0
https://pubmed.ncbi.nlm.nih.gov/33683765
https://pubmed.ncbi.nlm.nih.gov/33683765
Autor:
Valerie Wiemer, Ines Muke, Helmar C. Lehmann, Ilja Bobylev, Wolfram F. Neiss, Mohammed Barham, Alina Sprenger
Publikováno v:
Journal of Neuroimmunology. 343:577218
Data are sparse about mitochondrial damage in GBS and in its most frequently employed animal model, experimental autoimmune neuritis (EAN). We here characterized changes in mitochondrial content and morphology at different time points during EAN by u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee307e50a94b0ff475e47b3a75006229
https://doi.org/10.1016/j.jneuroim.2020.577218
https://doi.org/10.1016/j.jneuroim.2020.577218
ROCK inhibition improves axonal regeneration in a preclinical model of amyotrophic lateral sclerosis
Publikováno v:
The Journal of comparative neurology. 527(14)
Alteration of the RhoA/ROCK (Rho kinase) pathway has been shown to be neuroprotective in SOD1G93A mice, the most commonly used animal model of ALS. Since previous studies indicate that, apart from neuroprotection, ROCK inhibitor Y-27632 can also acce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b40aeb6e8b608b094d458c62f5d39ec8
https://pubmed.ncbi.nlm.nih.gov/30861116
https://pubmed.ncbi.nlm.nih.gov/30861116
Autor:
Helmar C. Lehmann, Abhijeet R. Joshi, Wolfram F. Neiss, Christian Ritter, Mohammed Barham, Ilja Bobylev, Ahmet Hoke
Publikováno v:
Neurobiology of Disease, Vol 82, Iss, Pp 321-331 (2015)
Paclitaxel is an integral component of solid tumor treatment. This chemotherapeutic agent provokes an often irreversible peripheral sensory neuropathy with pathological features of distal axonal degeneration. Current pathological concepts assume that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::310648bc51af92d67830d14c51689df3
https://doi.org/10.1016/j.nbd.2015.07.006
https://doi.org/10.1016/j.nbd.2015.07.006
Autor:
Helmar C. Lehmann, Mohammed Barham, Elke Pogge von Strandmann, Dominik Peters, Ines Klein, Ilja Bobylev, Maulik Vyas, Wolfram F. Neiss
Publikováno v:
Neurotoxicity research. 32(4)
Neurotoxicity is a relevant side effect of bortezomib treatment. Previous reports have shown that the development of peripheral neuropathy caused by anti-neoplastic agents may be a result of reduced axonal transport. Based on evidence from prior stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fa3b09ab3df2ccf21758fb065a4d38d
https://pubmed.ncbi.nlm.nih.gov/28612296
https://pubmed.ncbi.nlm.nih.gov/28612296
Publikováno v:
Molecular neurobiology. 55(2)
Sensory neuropathy is a relevant side effect of the antineoplastic agent cisplatin. Mitochondrial damage is assumed to play a critical role in cisplatin-induced peripheral neuropathy, but the pathomechanisms underlying cisplatin-induced mitotoxicity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96909a89d2df2c24f743d8603b29142b
https://pubmed.ncbi.nlm.nih.gov/28110471
https://pubmed.ncbi.nlm.nih.gov/28110471
Autor:
Toni Schneider, Christian Ritter, Abhijeet R. Joshi, Helmar C. Lehmann, Ilja Bobylev, Martin K.R. Svačina
Publikováno v:
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology. 12(1)
Fingolimod is a an oral disease modifying drug for relapsing remitting multiple sclerosis (MS) preventing egress of B and T cells from lymph nodes. Relevant first dose adverse events include bradycardia and atrioventricular conduction slowing. Cardia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::547d16a2691b6318e823cff7f75c6c16
https://pubmed.ncbi.nlm.nih.gov/28150133
https://pubmed.ncbi.nlm.nih.gov/28150133