Zobrazeno 1 - 10
of 179
pro vyhledávání: '"Ilio Vitale"'
Publikováno v:
Cell Death and Disease, Vol 12, Iss 2, Pp 1-3 (2021)
Externí odkaz:
https://doaj.org/article/b061004230974a23893ca6ec3c5c5af1
Autor:
Frauke Goeman, Francesca De Nicola, Carla Azzurra Amoreo, Stefano Scalera, Daniele Marinelli, Francesca Sperati, Marco Mazzotta, Irene Terrenato, Matteo Pallocca, Ludovica Ciuffreda, Eleonora Sperandio, Maddalena Barba, Laura Pizzuti, Domenico Sergi, Antonella Amodio, Giancarlo Paoletti, Eriseld Krasniqi, Patrizia Vici, Beatrice Casini, Enzo Gallo, Simonetta Buglioni, Maria Grazia Diodoro, Edoardo Pescarmona, Ilio Vitale, Ruggero De Maria, Gian Luca Grazi, Gennaro Ciliberto, Maurizio Fanciulli, Marcello Maugeri‐Saccà
Publikováno v:
Clinical and Translational Medicine, Vol 10, Iss 8, Pp n/a-n/a (2020)
Externí odkaz:
https://doaj.org/article/5bdf37083f3a42148bff33e644819592
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Cancer cell dormancy is a common feature of human tumors and represents a major clinical barrier to the long-term efficacy of anticancer therapies. Dormant cancer cells, either in primary tumors or disseminated in secondary organs, may reawaken and r
Externí odkaz:
https://doaj.org/article/df263a25f19d4ff691b63c714adab6eb
Autor:
Dmitriy Zamarin, Howard L Kaufman, Dobrin Draganov, Sofia R Gameiro, Ilio Vitale, Sandy Adjemian, Aitziber Buqué Martinez, Timothy A Chan, Richard L Edelson, Lucia Gabriele, Encouse Golden, Kevin J Harrington, Dewan Md Sakib Hossain, Michael Karin, Juan Jose Lasarte, Sherene Loi, Gwenola Manic, Alan A Melcher, Karen L Mossman, Maria Rescigno, Chiara Riganti, Antonella Sistigu, Bryan E Strauss, Kazuki Tatsuno, Stefaan W van Gool, Peter Vandenabeele
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 1 (2020)
Externí odkaz:
https://doaj.org/article/988b876661a144ee942a8a790aa6a723
Autor:
Dmitriy Zamarin, Howard L Kaufman, Dobrin Draganov, Sofia R Gameiro, Ilio Vitale, Sandy Adjemian, Aitziber Buqué Martinez, Timothy A Chan, Richard L Edelson, Lucia Gabriele, Encouse Golden, Kevin J Harrington, Dewan Md Sakib Hossain, Michael Karin, Juan Jose Lasarte, Sherene Loi, Gwenola Manic, Alan A Melcher, Karen L Mossman, Maria Rescigno, Chiara Riganti, Antonella Sistigu, Bryan E Strauss, Kazuki Tatsuno, Stefaan W van Gool, Peter Vandenabeele
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 1 (2020)
Cells succumbing to stress via regulated cell death (RCD) can initiate an adaptive immune response associated with immunological memory, provided they display sufficient antigenicity and adjuvanticity. Moreover, multiple intracellular and microenviro
Externí odkaz:
https://doaj.org/article/a9d90895f1e544d9989ad2cde51f79c0
Autor:
Anna Di Benedetto, Cristiana Ercolani, Marcella Mottolese, Francesca Sperati, Laura Pizzuti, Patrizia Vici, Irene Terrenato, Abeer M. Shaaban, Matthew P. Humphries, Luigi Di Lauro, Maddalena Barba, Ilio Vitale, Gennaro Ciliberto, Valerie Speirs, Ruggero De Maria, Marcello Maugeri-Saccà
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
Abstract The ATR-Chk1 and ATM-Chk2 pathways are central in DNA damage repair (DDR) and their over-activation may confer aggressive molecular features, being an adaptive response to endogenous DNA damage and oncogene-induced replication stress. Herein
Externí odkaz:
https://doaj.org/article/7b52d76921ce4c5b87a39faf7a697638
Autor:
Luca Mattiello, Sara Soliman Abdel Rehim, Martina Musella, Antonella Sistigu, Andrea Guarracino, Sara Vitale, Francesca Corradi, Claudia Galassi, Francesca Sperati, Gwenola Manic, Ruggero De Maria, Ilio Vitale
Publikováno v:
Cancers, Vol 13, Iss 8, p 1957 (2021)
Cancer stem cells (CSCs) drive not only tumor initiation and expansion, but also therapeutic resistance and tumor relapse. Therefore, CSC eradication is required for effective cancer therapy. In preclinical models, CSCs demonstrated high capability t
Externí odkaz:
https://doaj.org/article/243588b267864c5fabf92ef42fb2e44c
Autor:
Simonetta Buglioni, Elisa Melucci, Francesca Sperati, Matteo Pallocca, Irene Terrenato, Francesca De Nicola, Frauke Goeman, Beatrice Casini, Carla Azzurra Amoreo, Enzo Gallo, Maria Grazia Diodoro, Edoardo Pescarmona, Patrizia Vici, Domenico Sergi, Laura Pizzuti, Luigi Di Lauro, Marco Mazzotta, Maddalena Barba, Maurizio Fanciulli, Ilio Vitale, Ruggero De Maria, Gennaro Ciliberto, Marcello Maugeri-Saccà
Publikováno v:
OncoImmunology, Vol 7, Iss 8 (2018)
Whether PD-L1 expression is associated with survival outcomes in gastric cancer (GC) is controversial. The inhibition of the PD-1/PD-L1 pathway is effective against genomically unstable tumors. Hypothesizing that also the clinical significance of PD-
Externí odkaz:
https://doaj.org/article/42db658a29b24d8ab018b68d8259f40f
Publikováno v:
Molecular & Cellular Oncology, Vol 4, Iss 3 (2017)
Mitotic catastrophe is an oncosuppressive mechanism that targets cells experiencing defective mitoses via the activation of specific cell cycle checkpoints, regulated cell death pathways and/or cell senescence. This prevents the accumulation of karyo
Externí odkaz:
https://doaj.org/article/49ec480e6e66465e960ab55bdb09990f
Publikováno v:
OncoImmunology, Vol 6, Iss 5 (2017)
If there is a great new hope in the treatment of cancer, the immune system is it. Innate and adaptive immunity either promote or attenuate tumorigenesis and so can have opposing effects on the therapeutic outcome. Originally described as potent antiv
Externí odkaz:
https://doaj.org/article/366ebe8c600e4651a324b9e83793f59f