Sodium-dependent glucose co-transport proteins (SGLTs) are not involved in human glucose taste detection.

Autor: Palmer RK; Opertech Bio, Inc., Philadelphia, Pennsylvania, United States of America., Nechiporenko AB; Opertech Bio, Inc., Philadelphia, Pennsylvania, United States of America., Ilies MA; Department of Pharmaceutical Sciences and Moulder Center for Drug Discovery Research, School of Pharmacy, Temple University, Philadelphia, Pennsylvania, United States of America., Winnig M; AXXAM SpA, Bresso, Milan, Italy., Gravina SA; The Coca-Cola Company, Atlanta, Georgia, United States of America., Tiwari R; The Coca-Cola Company, Atlanta, Georgia, United States of America., Prakash I; The Coca-Cola Company, Atlanta, Georgia, United States of America.

Publikováno v: PloS one [PLoS One] 2024 Nov 18; Vol. 19 (11), pp. e0313128. Date of Electronic Publication: 2024 Nov 18 (Print Publication: 2024).

FDA-approved carbonic anhydrase inhibitors reduce amyloid β pathology and improve cognition, by ameliorating cerebrovascular health and glial fitness.

Autor: Canepa E; Alzheimer's Center at Temple, Department of Neural Sciences, Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania, USA., Parodi-Rullan R; Alzheimer's Center at Temple, Department of Neural Sciences, Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania, USA., Vazquez-Torres R; Alzheimer's Center at Temple, Department of Neural Sciences, Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania, USA., Gamallo-Lana B; Department of Neuroscience and Physiology, Neuroscience Institute, NYU Grossman School of Medicine, New York, New York, USA., Guzman-Hernandez R; Alzheimer's Center at Temple, Department of Neural Sciences, Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania, USA., Lemon NL; Alzheimer's Center at Temple, Department of Neural Sciences, Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania, USA., Angiulli F; Alzheimer's Center at Temple, Department of Neural Sciences, Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania, USA., Debure L; Department on Neurology, Center for Cognitive Neurology, NYU Grossman School of Medicine, New York, New York, USA., Ilies MA; Department of Pharmaceutical Sciences and Moulder Center for Drug Discovery Research, Temple University School of Pharmacy, Temple University, Philadelphia, Pennsylvania, USA., Østergaard L; Center of Functionally Integrative Neuroscience (CFIN), Department of Clinical Medicine, Aarhus University, Aarhus, Denmark., Wisniewski T; Department on Neurology, Center for Cognitive Neurology, NYU Grossman School of Medicine, New York, New York, USA., Gutiérrez-Jiménez E; Center of Functionally Integrative Neuroscience (CFIN), Department of Clinical Medicine, Aarhus University, Aarhus, Denmark., Mar AC; Department of Neuroscience and Physiology, Neuroscience Institute, NYU Grossman School of Medicine, New York, New York, USA., Fossati S; Alzheimer's Center at Temple, Department of Neural Sciences, Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania, USA.

Publikováno v: Alzheimer's & dementia : the journal of the Alzheimer's Association [Alzheimers Dement] 2023 Nov; Vol. 19 (11), pp. 5048-5073. Date of Electronic Publication: 2023 Apr 26.

Expression Dynamics of CA IX Epitope in Cancer Cells under Intermittent Hypoxia Correlates with Extracellular pH Drop and Cell Killing by Ureido-Sulfonamide CA IX Inhibitors.

Autor: Sufian MA; Department of Pharmaceutical Sciences and Moulder Center for Drug Discovery Research, School of Pharmacy, Temple University, 3307 North Broad Street, Philadelphia, PA 19140, USA., Zamanova S; Department of Pharmaceutical Sciences and Moulder Center for Drug Discovery Research, School of Pharmacy, Temple University, 3307 North Broad Street, Philadelphia, PA 19140, USA., Shabana AM; Department of Pharmaceutical Sciences and Moulder Center for Drug Discovery Research, School of Pharmacy, Temple University, 3307 North Broad Street, Philadelphia, PA 19140, USA.; Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Cairo University, Cairo 11562, Egypt., Kemp B; Department of Pharmaceutical Sciences and Moulder Center for Drug Discovery Research, School of Pharmacy, Temple University, 3307 North Broad Street, Philadelphia, PA 19140, USA., Mondal UK; Department of Pharmaceutical Sciences and Moulder Center for Drug Discovery Research, School of Pharmacy, Temple University, 3307 North Broad Street, Philadelphia, PA 19140, USA., Supuran CT; NEUROFARBA Department, Pharmaceutical Sciences Section, Universita degli Studi di Firenze, Polo Scientifico, Via Ugo Schiff No. 6, 50019 Sesto Fiorentino, Florence, Italy., Ilies MA; Department of Pharmaceutical Sciences and Moulder Center for Drug Discovery Research, School of Pharmacy, Temple University, 3307 North Broad Street, Philadelphia, PA 19140, USA.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2023 Feb 27; Vol. 24 (5). Date of Electronic Publication: 2023 Feb 27.

Evaluation of the Impact of Esterases and Lipases from the Circulatory System against Substrates of Different Lipophilicity.

Autor: Lam L; College of Science and Technology, Temple University, 1803 N. Broad Street, Philadelphia, PA 19122, USA., Ilies MA; Department of Pharmaceutical Sciences and Moulder Center for Drug Discovery Research, Temple University School of Pharmacy, 3307 N Broad Street, Philadelphia, PA 19140, USA.; Lewis Katz School of Medicine, Alzheimer's Center (ACT), Temple University, Philadelphia, PA 19140, USA.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2022 Jan 23; Vol. 23 (3). Date of Electronic Publication: 2022 Jan 23.

PEG Linker Length Strongly Affects Tumor Cell Killing by PEGylated Carbonic Anhydrase Inhibitors in Hypoxic Carcinomas Expressing Carbonic Anhydrase IX.

Autor: Mondal UK; Department of Pharmaceutical Sciences, Moulder Center for Drug Discovery Research, Temple University School of Pharmacy, 3307 N Broad Street, Philadelphia, PA 19140, USA., Doroba K; Department of Pharmaceutical Sciences, Moulder Center for Drug Discovery Research, Temple University School of Pharmacy, 3307 N Broad Street, Philadelphia, PA 19140, USA., Shabana AM; Department of Pharmaceutical Sciences, Moulder Center for Drug Discovery Research, Temple University School of Pharmacy, 3307 N Broad Street, Philadelphia, PA 19140, USA.; Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Cairo University, Cairo 11562, Egypt., Adelberg R; Department of Pharmaceutical Sciences, Moulder Center for Drug Discovery Research, Temple University School of Pharmacy, 3307 N Broad Street, Philadelphia, PA 19140, USA., Alam MR; Department of Pharmaceutical Sciences, Moulder Center for Drug Discovery Research, Temple University School of Pharmacy, 3307 N Broad Street, Philadelphia, PA 19140, USA., Supuran CT; NEUROFARBA Department, Pharmaceutical Sciences Section, Universita degli Studi di Firenze, Polo Scientifico, via Ugo Schiff no. 6, 50019 Sesto Fiorentino (Florence), Italy., Ilies MA; Department of Pharmaceutical Sciences, Moulder Center for Drug Discovery Research, Temple University School of Pharmacy, 3307 N Broad Street, Philadelphia, PA 19140, USA.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2021 Jan 23; Vol. 22 (3). Date of Electronic Publication: 2021 Jan 23.